Bioprinted organs and tissue models are two primary applications of bioprinting, but they have long been criticised for immaturity and low clinical relevance despite some commercial successes. The factors causing such general inadequacies are multiple and complex. Even the question of vascularization has not been well answered after nearly three decades. However, the accumulation of stepwise or incremental improvements is essential before a breakthrough falls on mankind. Therefore, this column aims to collect the on-going research focuses on all the approaches that effectively leads to better tissue or organ outcomes than before, as well as the current thinking of clinical translation of bioprinting.
A 3D bioprinted tumor model fabricated with gelatin/sodium alginate/decellularized extracellular matrix bioink
FeS2-incorporated 3D PCL scaffold improves new bone formation and neovascularization in a rat calvarial defect model
Multifunctional 3D platforms for rapid hemostasis and wound healing: Structural and functional prospects at biointerfaces
The first 3D-bioprinted personalized active bone to repair bone defects: A case report
Toward better drug development: Three-dimensional bioprinting in toxicological research
Manufacturing flexible vascular models for cardiovascular surgery planning and endovascular procedure simulations: An approach to segmentation and post-processing with open-source software and end-user 3D printers
Bioprinting of hydrogel beads to engineer pancreatic tumor-stroma microtissues for drug screening
Study on drug screening multicellular model for colorectal cancer constructed by three-dimensional bioprinting technology
Meniscus heterogeneity and 3D-printed strategies for engineering anisotropic meniscus
Co-culture bioprinting of tissue-engineered bone-periosteum biphasic complex for repairing critical-sized skull defects in rabbits
3D-printed vascularized biofunctional scaffold for bone regeneration
Tissue-engineered edible bird’s nests (TeeBN)
Biomimetic three-dimensional glioma model printed in vitro for the studies of glioma cells and neurons interactions
Using 3D-bioprinted models to study pediatric neural crest-derived tumors
3D-printed gradient scaffolds for osteochondral defects: Current status and perspectives
Machine learning boosts three-dimensional bioprinting
Functional materials of 3D bioprinting for wound dressings and skin tissue engineering applications: A review
Hydrogels for 3D bioprinting in tissue engineering and regenerative medicine: Current progress and challenges
A sturgeon cartilage extracellular matrix-derived bioactive bioink for tissue engineering applications
Organoid bioprinting strategy and application in biomedicine: A review