Dear Colleagues:

To improve the quality of life, when considering cancer disease, an increasing number and structure of nanomedicines and/or theragnostic tools were developed to prevent, diagnose and treat the diseases. But those scientific advances have to face a low rate when considering the reaching of the clinical trial stage. The difference in human physiology makes than the development of relevant in vitro cancer models crucial to efficiently assess and develop new anticancer molecules.  For instance, three-dimensional cell cultures and organ-on-chips devices are the best alternatives due to their ability to simulate cell-cell interactions and oxygen and nutrient gradients found in vivo. In this area, 3D bioprinting is a promising approach to generate reproducible and robust 3D tumor models. This computer assisted process enable the elaboration of 3D multi-cell constructs with a controlled architecture and a high reproducibility. This special issue aims then to emerge all the most relevant work presenting the high potential of 3D bioprinting for the cancer model developments.