AccScience Publishing / IJB / Volume 9 / Issue 6 / DOI: 10.36922/ijb.0112
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REVIEW

Organoid bioprinting strategy and application in biomedicine: A review

Chen He1 Jiasheng Yan2 Yusheng Fu1 Jiuchuan Guo1 Yuxing Shi1 Jinhong Guo1,2*
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1 School of Information and Communication Engineering, University of Electronic Science and Technology of China, Chengdu, China
2 School of Sensing Science and Engineering, Shanghai Jiao Tong University, Shanghai, China
Submitted: 3 April 2023 | Accepted: 16 May 2023 | Published: 30 June 2023
© 2023 by the Author(s). This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution 4.0 International License ( https://creativecommons.org/licenses/by/4.0/ )
Abstract

Organoids are three-dimensional cell structures cultured in vitro. They are self-organizing and can mimic real organs in structure and function. Bioprinting technology breaks through some limitations of organoid manufacturing, making it more widely used in drug screening, regenerative medicine, and other fields. In this review, we first introduce bioinks and bioprinting methods for stem cell and organoid bioprinting, then summarize several vascularization strategies for bioprinting organoids, and present applications in biomedicine. In the future, the development of microfluidic technology and four-dimensional bioprinting technology may be conducive to forming better bioprinted organoids.

Keywords
Bioprinting
Organoid
Tissue engineering
Funding
This work is funded by the financial support from National Natural Science Foundation of China (62122017).
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Conflict of interest
The authors declare no conflict of interest.
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International Journal of Bioprinting, Electronic ISSN: 2424-8002 Print ISSN: 2424-7723, Published by AccScience Publishing