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Column
With the rapid development of different disciplines, we have set up Column to deeply explore, comprehensively report, and focus on highly innovative and highly academically valuable scientific research results in the research fields covered by each journal. Column brings together the best topics selected by the Editor-in-Chief’s and Editorial Board’s teams based on the future academic trends and the latest research hotspots of different disciplines around the world to publish high-quality scientific research and academic results after soliciting contributions and rigorous peer review.
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Neurological and Psychiatric Disorders
Summary: The complexities of neurological and psychiatric disorders stem from an intricate web of causative factors, ranging from genetic to environmental and biochemical. Investigations into neuronal function, synaptic communication, genetic mutations, and their interactions with environmental factors are instrumental in decoding the manifestation of related symptoms. A profound comprehension of these fundamental processes is essential for conceiving enhanced therapeutic methods.
Release date: 2024
Vascular Diseases
Summary: Age-related endothelial and smooth muscle cell dysfunctions play a pivotal role in the development of various cardiovascular and vascular disorders, including atherosclerosis, hypertension, and vascular stiffness. This column investigates innovative therapeutic approaches aimed at mitigating the deleterious effects of aging on vascular cells, thus addressing the root causes of age-related vascular diseases. The age-related decline in endothelial function, characterized by impaired nitric oxide production and increased oxidative stress, contributes to endothelial dysfunction. Similarly, aging-associated alterations in smooth muscle cells lead to vascular stiffness and maladaptive remodeling.
Release date: 2024
Biofilm formation in Healthcare
Summary: The production of biofilm is one of the most important survival strategies utilised by bacteria in a variety of environments. Biofilms are natural component of the surfaces of the body, including the skin and the mucosal surfaces of the respiratory and digestive systems. The production of biofilm can have some beneficial consequences, similar to those generated by commensals; nevertheless, in most instances, biofilms are connected with infection, such as those seen in chronic wounds and cystic fibrosis. Biofilms shield microorganisms from the immune system of their host, which enables them to establish themselves and provides support for chronicity. In addition to that, it improves antibiotic tolerance. Research on how biofilms are created, their toxicity, and various ways for battling them have risen to the forefront of infectious biology and medicine in recent years as the prevalence of this phenomenon has increased.
Release date: 2023
Protease Research in Molecular Mechanisms
Summary: Proteases, are a diverse group of enzymes that play critical roles in a wide range of biological processes, including protein degradation, cell signaling, and inflammation. Dysregulation of proteolytic activity has been implicated in the pathogenesis of various diseases, including cancer, neurodegenerative disorders, and inflammatory conditions.
Release date: 2023