Gene & Protein in Disease is an open-access journal under AccScience Publishing. All articles published in Gene & Protein in Disease can be freely accessed from the journal website. In order to ensure contents are freely available and maintain publishing quality, Article Process Charges (APC) are levied on all authors whose papers are accepted for publication after peer-review to cover the costs incurred in manuscript processing, such as copy-editing, typesetting, publishing, content depositing and archiving processes. Articles that do not require peer-review such as letters, editorials, corrigenda, and addenda will be published free of charge. For more details, please refer to AccScience Publishing Article Processing Charges.

In Gene & Protein in Disease, withdrawal of a submission refers to the removal of a new submission, a paper currently under peer-review, an accepted paper, or an Article in Press from the online submission system. In the event that authors insist to withdraw a submission on unethical and unreasonable grounds (see the link: https://accscience.com/information/apc mentioned *unethical and unreasonable reasons*), a submission withdrawal fee at 30% of the prevailing Article Processing Charge will be levied on the authors. Submission withdrawal is also possible for accepted papers that have not been formally published, including the newly accepted papers and Articles in Press. Authors should note that any amounts of paid Article Processing Charge will not be refunded if their accepted papers or Articles in Press are withdrawn on the grounds of academic misconducts and ethical violations in research and publication.

APC Waiver and Discount Policy, please refer to the Publisher Uniform Rules.