AccScience Publishing / GPD / Online First / DOI: 10.36922/gpd.1230
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Unleashing the potential of stem cells for targeted antimicrobial treatment

Ali Yetgin1,2*
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1 Toros Agri Industry and Trade Co. Inc., Research and Development Center, Mersin, Turkey
2 Cukurova University, Institute of Nature and Applied Sciences, Department of Biotechnology, Adana, Turkey
GPD 2023, 2(4), 1230 https://doi.org/10.36922/gpd.1230
Submitted: 3 July 2023 | Accepted: 20 September 2023 | Published: 6 December 2023
© 2023 by the Author(s). This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution 4.0 International License ( https://creativecommons.org/licenses/by/4.0/ )
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Abstract

Infectious diseases continue to pose a serious threat to human health as a result of the spread of antibiotic resistance, underscoring the urgent need for new and focused therapeutic approaches. Due to their regenerative and immunomodulatory capabilities, stem cells have emerged as a potential source for the development of antimicrobial therapies. This paper reviews the potential of stem cells as a targeted strategy for combating infections, focusing on their ability to differentiate into specific cell types that can directly target and eliminate microorganisms, as well as their capacity to modulate the immune response and enhance host defenses. The article discusses the challenges and opportunities associated with the clinical implementation of antimicrobial therapies derived from stem cells. Among these obstacles are the need for uniform protocols for cell isolation, expansion, and delivery, as well as the significance of rigorous evaluations of safety and efficacy. Despite that, the application of stem cells as a targeted antimicrobial approach holds significant potential for the development of effective and enduring therapeutic interventions for infectious diseases.

Keywords
Stem cells
Antimicrobial therapy
Targeted delivery
Regenerative medicine
Host defense mechanisms
Funding
None.
Conflict of interest
The author declares no competing interests.
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