The World Health Organization Disability Assessment Schedule 2.0 as a global metric of functioning: Implications for health economics and sustainable health systems
Disability is an increasingly important driver of healthcare utilization, long-term care needs, and health system sustainability worldwide. The World Report on Disability marked a major shift in understanding disability as a global health and development issue, emphasizing functioning, participation, and environmental barriers within the International Classification of Functioning, Disability and Health (ICF) framework. As population aging and chronic conditions increase the global burden of disability, robust measures are needed to assess functioning alongside traditional indicators of mortality and morbidity. The World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0), developed within the ICF framework, provides a standardized and cross-culturally applicable measure of functioning and disability. This conceptual review examines the potential contribution of WHODAS 2.0 to population health measurement, health economics, and sustainable health policy. Although disability-adjusted life years and quality-adjusted life years dominate population health assessments and economic evaluations, functioning remains insufficiently represented in these frameworks. WHODAS 2.0 directly assesses functioning based on individuals’ everyday experiences and complements burden-of-disease and utility-based metrics by capturing domains that conventional indicators may overlook. Integrating functioning into population health assessment could support disability assessment, outcome monitoring, policy development, health system evaluation, and economic evaluation. We argue that WHODAS 2.0 is the most mature operational candidate currently available for measuring functioning at the population level and for advancing functioning as a third core health indicator alongside mortality and morbidity.
Albrecht, G. L., & Devlieger, P. J. (1999). The disability paradox: High quality of life against all odds. Social Science & Medicine, 48(8), 977–988. https://doi.org/10.1016/S0277-9536(98)00411-0
American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders: DSM-iv-tr. American Psychiatric Association. http://books.google.com/books?id=3SQrtpnHb9MC
American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders, fifth edition. American Psychiatric Association. https://doi.org/10.1176/appi.books.9780890425596
American Psychiatric Association. (2022). Diagnostic and statistical manual of mental disorders, fifth edition, text revision (DSM-5-tr). American Psychiatric Association. https://doi.org/10.1176/appi.books.9780890425787
Brazier, J., Roberts, J., & Deverill, M. (2002). The estimation of a preference-based measure of health from the sf-36. Journal of Health Economics, 21(2), 271–292. https://doi.org/10.1016/s0167-6296(01)00130-8
Brazier, J., & Tsuchiya, A. (2010). Preference-based condition-specific measures of health: What happens to cross programme comparability? Health Economics, 19(2), 125–129. https://doi.org/10.1002/hec.1580
Brooks, R. (1996). Euroqol: The current state of play. Health Policy, 37(1), 53–72. https://doi.org/10.1016/0168-8510(96)00822-6
Cieza, A., Causey, K., Kamenov, K., Hanson, S. W., Chatterji, S., & Vos, T. (2020). Global estimates of the need for rehabilitation based on the Global Burden of Disease Study 2019: A systematic analysis for the Global Burden of Disease Study 2019. The Lancet, 396(10267), 2006–2017. https://doi.org/10.1016/S0140-6736(20)32340-0
Cieza, A., Sabariego, C., Bickenbach, J., & Chatterji, S. (2018). Rethinking disability. BMC Medicine, 16(1), 14. https://doi.org/10.1186/s12916-017-1002-6
Drummond, M. F., Sculpher, M. J., Claxton, K., Stoddart, G. L., & Torrance, G. W. (2015). Methods for the economic evaluation of health care programmes (4th ed.). Oxford University Press. https://doi.org/10.1093/oso/9780198529446.001.0001
Federici, S., Balboni, G., Buracchi, A., Barbanera, F., & Pierini, A. (2023). WHODAS-child: Psychometric properties of the WHODAS 2.0 for children and youth among Italian children with autism spectrum disorder. Disability and Rehabilitation, 45(10), 1713–1719. https://doi.org/10.1080/09638288.2022.2071481
Federici, S., Bracalenti, M., Meloni, F., & Luciano, J. V. (2017). World health organization disability assessment schedule 2.0: An international systematic review. Disability and Rehabilitation, 39(23), 2347–2380. https://doi.org/10.1080/09638288.2016.1223177
Federici, S., Meloni, F., & Corradi, F. (2018). Measuring individual functioning. In S. Federici & M. J. Scherer (Eds.), Assistive technology assessment handbook (2nd ed., pp. 27–51). CRC Press.
Federici, S., Tosti, A., Russo, E. A., & Conigli, L. (2026). Measurement characteristics of WHODAS 2.0 and WHODAS-child: A systematic review of global psychometric studies in specific populations since 2010. Frontiers in Psychiatry, 17(1737452), 1–19. https://doi.org/10.3389/fpsyt.2026.1737452
Feeny, D., Furlong, W., Boyle, M., & Torrance, G. W. (1995). Multi-attribute health status classification systems: Health utilities index. Pharmacoeconomics, 7(6), 490–502. https://doi.org/10.2165/00019053-199507060-00004
Ferrari, A. J., Santomauro, D. F., Aali, A., Abate, Y. H., Abbafati, C., Abbastabar, H., Abd ElHafeez, S., Abdelmasseh, M., Abd-Elsalam, S., Abdollahi, A., Abdullahi, A., Abegaz, K. H., Abeldaño Zuñiga, R. A., Aboagye, R. G., Abolhassani, H., Abreu, L. G., Abualruz, H., Abu-Gharbieh, E., Abu-Rmeileh, N. M. E., . . . Murray, C. J. L. (2024). Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990-2021: A systematic analysis for the Global Burden of Disease Study 2021. The Lancet, 403(10440), 2133–2161. https://doi.org/10.1016/S0140-6736(24)00757-8
Gimigliano, F., & Negrini, S. (2017). The world health organization “rehabilitation 2030: A call for action”. European Journal of Physical and Rehabilitation Medicine, 53(2), 155–168. https://doi.org/10.23736/S1973-9087.17.04746-3
Global Burden of Disease Collaborative Network. (2024). Global burden of disease study 2021 (gbd 2021) results. https://doi.org/10.6069/gd60-d685
Hall, J. M., De Silva, N. L., Ruben, J., Thilakarathne, S. S., Yahathugoda, T. C., & Budge, P. J. (2024). Efficacy and feasibility of short-stretch compression therapy for filarial lymphedema in sri lanka. The American Journal of Tropical Medicine and Hygiene, 110(5), 936–942. https://doi.org/10.4269/ajtmh.23-0496
Krahn, G. L. (2011). Who world report on disability: A review. Disability and Health Journal, 4(3), 141–142. https://doi.org/10.1016/j.dhjo.2011.05.001
Liu, X., Wang, Y., Wang, F., Zhou, H., Zhang, Q., Meng, R., Yu, Y., Liu, Y., & Yu, C. (2025). Estimated disability weights for the severity of health outcomes: A systematic review and meta-analysis. Population Health Metrics, 23(1), 62. https://doi.org/10.1186/s12963-025-00425-6
Lokkerbol, J., Wijnen, B. F. M., Chatterji, S., Kessler, R. C., & Chisholm, D. (2021). Mapping of the world health organization’s disability assessment schedule 2.0 to disability weights using the multi-country survey study on health and responsiveness. International Journal of Methods in Psychiatric Research, 30(3), e1886. https://doi.org/10.1002/mpr.1886
Ma, B. H., Chen, G., Badji, S., & Petrie, D. (2024). Mapping the 12-item world health organization disability assessment schedule 2.0 (WHODAS 2.0) onto the assessment of quality of life (aqol)-4d utilities. Quality of Life Research, 33(2), 411–422. https://doi.org/10.1007/s11136-023-03532-9
Murray, C. J. L. (1994). Quantifying the burden of disease: The technical basis for disability-adjusted life years. Bulletin of The World Health Organization, 72(3), 429–445.
Murray, C. J. L., & Chen, L. C. (1992). Understanding morbidity change. Population And Development Review, 18(3), 481–503. https://doi.org/10.2307/1973655
Murray, C. J. L., & Lopez, A. D. (1996). The global burden of disease: A comprehensive assessment of mortality and disability from diseases, injuries, and risk factors in 1990 and projected to 2020 (Vol. 1). Harvard School of Public Health.
Murray, C. J. L., Vos, T., Lozano, R., Naghavi, M., Flaxman, A. D., Michaud, C., Ezzati, M., Shibuya, K., Salomon, J. A., Abdalla, S., Aboyans, V., Abraham, J., Ackerman, I., Aggarwal, R., Ahn, S. Y., Ali, M. K., AlMazroa, M. A., Alvarado, M., Anderson, H. R., . . . Lopez, A. D. (2012). Disability-adjusted life years (dalys) for 291 diseases and injuries in 21 regions, 1990–2010: A systematic analysis for the global burden of disease study 2010. The Lancet, 380(9859), 2197–2223. https://doi.org/10.1016/S0140-6736(12)61689-4
Porter, M. E. (2010). What is value in health care? New England Journal of Medicine, 363(26), 2477–2481. https://doi.org/doi:10.1056/NEJMp1011024
Porter, M. E., & Lee, T. H. (2013). The strategy that will fix health care. Harvard Business Review, 91(10), 50–70.
Repubblica Italiana. (2024). Decreto legislativo 3 maggio 2024, n. 62. Definizione della condizione di disabilità, della valutazione di base, di accomodamento ragionevole, della valutazione multidimensionale per l’elaborazione e attuazione del progetto di vita individuale personalizzato e partecipato. (24g00079) [Legislative Decree No. 62 of May 3, 2024. Definition of disability, basic assessment, reasonable accommodation, and multidimensional assessment for the development and implementation of personalized and participatory individual life plans.]. Gazzetta Ufficiale della Repubblica Italiana, Serie Generale 105 [In Italian]. https://www.normattiva.it/uri-res/N2Ls?urn:nir:stato:decreto.legislativo:2024-05-03;62​:contentReference[oaicite:2
Salomon, J. A., Haagsma, J. A., Davis, A., de Noordhout, C. M., Polinder, S., Havelaar, A. H., Cassini, A., Devleesschauwer, B., Kretzschmar, M., Speybroeck, N., Murray, C. J. L., & Vos, T. (2015). Disability weights for the global burden of disease 2013 study. The Lancet Global Health, 3(11), e712–e723. https://doi.org/10.1016/S2214-109X(15)00069-8
Sen, A. (2002). Health: Perception versus observation. British Medical Journal (Clinical Research Edition), 324(7342), 860–861. https://doi.org/10.1136/bmj.324.7342.860
Stucki, G., & Bickenbach, J. E. (2017). Functioning: The third health indicator in the health system and the key indicator for rehabilitation. European Journal of Physical and Rehabilitation Medicine, 53(1), 134–138. https://doi.org/10.23736/S1973-9087.17.04565-8
Stucki, G., Bickenbach, J. E., & Melvin, J. (2017). Strengthening rehabilitation in health systems worldwide by integrating information on functioning in national health information systems. American Journal of Physical Medicine & Rehabilitation, 96(9), 677–681. https://doi.org/10.1097/phm.0000000000000688
Torrance, G. W. (1986). Measurement of health state utilities for economic appraisal: A review. Journal of Health Economics, 5(1), 1–30. https://doi.org/10.1016/0167-6296(86)90020-2
Ubel, P. A., Loewenstein, G., & Jepson, C. (2005). Disability and sunshine: Can hedonic predictions be improved by drawing attention to focusing illusions or emotional adaptation? Journal of Experimental Psychology: Applied, 11(2), 111–123. https://doi.org/10.1037/1076-898X.11.2.111
United Nations. (2006). Convention on the rights of persons with disabilities. UN. https://www.un.org/disabilities/documents/convention/convoptprot-e.pdf
Üstün, T. B., Kostanjsek, N., Chatterji, S., & Rehm, J. (2010). Measuring health and disability: Manual for who disability assessment schedule (WHODAS 2.0). World Health Organization. http://whqlibdoc.who.int/publications/2010/9789241547598_eng.pdf
Vos, T., Lim, S. S., Abbafati, C., Abbas, K. M., Abbasi, M., Abbasifard, M., Abbasi-Kangevari, M., Abbastabar, H., Abd-Allah, F., Abdelalim, A., Abdollahi, M., Abdollahpour, I., Abolhassani, H., Aboyans, V., Abrams, E. M., Abreu, L. G., Abrigo, M. R. M., Abu-Raddad, L. J., Abushouk, A. I., . . . Murray, C. J. L. (2020). Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: A systematic analysis for the global burden of disease study 2019. The Lancet, 396(10258), 1204–1222. https://doi.org/10.1016/S0140-6736(20)30925-9
Weerasinghe, I. E., Fonseka, P., Dharmaratne, S. D., & Jayatilake, J. A. M. S. (2015). Prevalence of physical disability among urban community-dwelling adults in sri lanka. Disability, CBR & Inclusive Development, 26(2), 65–91. https://doi.org/10.5463/dcid.v26i2.412
Whitehead, S. J., & Ali, S. (2010). Health outcomes in economic evaluation: The qaly and utilities. British Medical Bulletin, 96(1), 5–21. https://doi.org/10.1093/bmb/ldq033
World Health Organization. (1980). International classification of impairments, disabilities, and handicaps. A manual of classification relating to the consequences of disease. World Health Organization.
World Health Organization. (2001). International classification of functioning, disability and health: ICF. https://www.who.int/standards/classifications/international-classification-of-functioning-disability-and-health
World Health Organization. (2017). Rehabilitation 2030: A call for actions. World Health Organization.
World Health Organization. (2022). International classification of diseases 11th revision (ICD-11). World Health Organization. https://icd.who.int/
World Health Organization, & World Bank. (2011). World report on disability. World Health Organization. https://www.who.int/publications/i/item/WHO-NMH-VIP-11.01
