Adebamowo, C., Rossi, P. G., & Castle, P. E. (2025). Challenges and opportunities for global cervical cancer elimination: How can we build a model for other cancers? ASCO Educational Book, 45, e473702. https://doi.org/10.1200/EDBK-25-473702

Aria, M., & Cuccurullo, C. (2017). Bibliometrix: An R-tool for comprehensive science mapping analysis. Journal of Informetrics, 11(4), 959–975. https://doi.org/10.1016/j.joi.2017.08.007

Bornmann, L., & Leydesdorff, L. (2014). Scientometrics in a changing research landscape. EMBO Reports, 15, 1228– 1232. https://doi.org/10.15252/embr.201439608

Brasil. Ministério da Saúde. Comissão Nacional de Incorporação de Tecnologias no Sistema Único de Saúde (CONITEC). (2013). Vacina contra HPV na prevenção de câncer de colo do útero: Julho de 2013 [HPV vaccine for the prevention of cervical cancer: July 2013]. [In Portuguese] Available online: https://www.gov.br/conitec/pt-br/midias/incorporados/ vacinahpv-final.pdf/view (accessed on February 20, 2025).

Brasil. Ministério da Saúde. (2014a). Informe técnico sobre a vacina papilomavírus humano (HPV) na atenção básica [Technical report on the human papillomavirus (HPV) vaccine in primary care]. [In Portuguese] Available online: https://goias.gov.br/saude/wp-content/uploads/ sites/34/2014/02/informe-tec_introducao-vacina-hpv-49e. pdf (accessed on February 20, 2025).

Brasil. Ministério da Saúde. (2014b). Manual de normas e procedimentos para vacinação [Manual of vaccination procedures]. [In Portuguese] Available online: https://bvsms. saude.gov.br/bvs/publicacoes/manual_procedimentos_ vacinacao.pdf (accessed on April 16, 2025).

Brasil. Ministério da Saúde. Secretaria de Vigilância em Saúde e Ambiente. Departamento de Ações Estratégicas de Epidemiologia e Vigilância em Saúde e Ambiente. (2024a). Guia de vigilância em saúde: Volume 1 (6ª ed.) [Health surveillance guide: Volume 1]. [In Portuguese] Available online: https://vigilancia.saude.rr.gov.br/wp-content/ uploads/2024/09/Guia-de-Vigilancia-em-Saude-2024- vol.-1.pdf (accessed on February 17, 2025).

Brasil. Ministério da Saúde. (2024b). Nota Técnica nº 41/2024- CGICI/DPNI/SVSA/MS: Atualização das recomendações da vacinação contra HPV no Brasil [Technical Note No. 41/2024-CGICI/DPNI/SVSA/MS: Update of HPV vaccination recommendations in Brazil]. [In Portuguese] Available online: https://www.gov.br/saude/pt-br/centrais-de-conteudo/publicacoes/notas-tecnicas/2024/nota-tecnica-no-41-2024-cgici-dpni-svsa-ms (accessed on February 20, 2025).

Brisson, M., Kim, J. J., Canfell, K., Drolet, M., Gingras, G., Burger, E. A., Martin, D., Simms, K. T., Bénard, É., Boily, M.-C., Sy, S., Regan, C., Keane, A., Caruana, M., Nguyen, D. T. N., Smith, M. A., Laprise, J.-F., Jit, M., Alary, M., & Bray, F. (2020). Impact of HPV vaccination and cervical screening on cervical cancer elimination: A comparative modelling analysis in 78 low-income and lower-middle-income countries. The Lancet, 395(10224), 575–590. https://doi.org/10.1016/S0140-6736(20)30068-4

Bruni, L., Albero, G., Rowley, J., Alemany, L., Arbyn, M., Giuliano, A. R., Markowitz, L. E., Broutet, N., & Taylor, M. (2023). Global and regional estimates of genital human papillomavirus prevalence among men: A systematic review and meta-analysis. The Lancet Global Health, 11(9), e1345– e1362. https://doi.org/10.1016/S2214-109X(23)00305-4

Campos, N. G., Lowy, D. R., de Sanjosé, S., & Schiffman, M. (2024). A cervical cancer control strategy for lower-resource settings: Interventions to complement one-dose HPV vaccination. JNCI Monographs, 2024(67), 417–423. https://doi.org/10.1093/jncimonographs/lgae040

Cerqueira-Silva, T., Barral-Netto, M., & Boaventura, V. S. (2025). Effect of Brazil’s national human papillomavirus vaccination programme on the incidence of cervical cancer and cervical intraepithelial neoplasia grade 3 in women aged 20–24 years: a population-based study. The Lancet Global Health, 13(10), e1715–e1722. https://doi.org/10.1016/S2214-109X(25)00279-7

Couto, L. F., & Rodrigues, J. M. (Eds.). (2022). Governança orçamentária no Brasil [Budget governance in Brazil]. Rio de Janeiro e Brasília: Instituto de Pesquisa Econômica Aplicada (IPEA) e Comissão Econômica para a América Latina e o Caribe (CEPAL). [In Portuguese] https://doi.org/10.38116/978-65-5635-043-1

Diaz-Obregón, D. Z., Coila-Paricahua, E., Soto-Becerra, P., Rojas, C. A. O., & Murillo Carrasco, A. G. (2025). Development of a health research portfolio based on priority topics for Peruvian Social Health Insurance (ESSALUD) in 2023– 2025. Healthcare, 13(5), 514. https://doi.org/10.3390/healthcare13050514

Domingues, C. M. A. S., Maranhão, A. G. K., Teixeira, A. M., Fantinato, F. F. S., & Domingues, R. A. S. (2020). 46 anos do Programa Nacional de Imunizações: Uma história repleta de conquistas e desafios a serem superados [46 years of the National Immunization Program: A history full of achievements and challenges to be overcome]. Cadernos de Saúde Pública, 36(Suppl. 2), e00222919. [In Portuguese] https://doi.org/10.1590/0102-311x00222919

Domingues, C. M. A. S., Woycicki, J. R., Rezende, K. S., & Henriques, C. M. P. (2015). Programa nacional de imunização: A política de introdução de novas vacinas [National Immunization Program: The policy for introducing new vaccines]. Revista Eletrônica de Gestão & Saúde, 6(4), 3250–3274. [In Portuguese] Available online: https://periodicos.unb.br/index.php/rgs/article/view/3331 (accessed on April 16, 2025).

Drolet, M., Bénard, É., Pérez, N., Brisson, M., Ali, H., Boily, M.-C., Baldo, V., Brassard, P., Brotherton, J. M. L., Callander, D., Checchi, M., Chow, E. P. F., Cocchio, S., Dalianis, T., Deeks, S. L., Dehlendorff, C., Donovan, B., Fairley, C. K., Flagg, E. W., … Yu, B. N. (2019). Population-level impact and herd effects following the introduction of human papillomavirus vaccination programmes: Updated systematic review and meta-analysis. The Lancet, 394(10197), 497–509. https://doi.org/10.1016/S0140-6736(19)30298-3

Drummond, M. F., Sculpher, M. J., Claxton, K., Stoddart, G. L., & Torrance, G. W. (2015). Methods for the economic evaluation of health care programmes (4th ed.). Oxford University Press.

Duan, C. (2024). Analyses of scientific collaboration networks among authors, institutions, and countries in FinTech studies: A bibliometric review. FinTech, 3(2), 249–273. https://doi.org/10.3390/fintech3020015

Falagas, M. E., Pitsouni, E. I., Malietzis, G. A., & Pappas, G. (2008). Comparison of PubMed, Scopus, Web of Science, and Google Scholar: Strengths and weaknesses. The FASEB Journal, 22(2), 338–342. https://doi.org/10.1096/fj.07-9492lsf

Falcaro, M., Castañon, A., Ndlela, B., Checchi, M., Soldan, K., Lopez-Bernal, J., Elliss-Brookes, L., & Sasieni, P. (2021). The effects of the national HPV vaccination programme in England, UK, on cervical cancer and grade 3 cervical intraepithelial neoplasia incidence: A register-based observational study. The Lancet, 398(10316), 2623–2634. https://doi.org/10.1016/S0140-6736(21)02178-4

Fernandes, D. R. A., Gadelha, C. A. G., & Maldonado, J. M. S. V. (2023). Estratégias de inovação em medicamentos e vacinas no âmbito do Ceis: Modelos, mecanismos e expectativas [Innovation strategies in medicines and vaccines within the scope of CEIS: Models, mechanisms, and expectations]. Saúde em Debate, 47(138), 377–392. [In Portuguese] https://doi.org/10.1590/0103-1104202313801i

Figueiredo, J. O., Prado, N. M. B. L., Medina, M. G., & Paim, J. S. (2018). Gastos público e privado com saúde no Brasil e países selecionados [Public and private health expenditures in Brazil and selected countries]. Saúde em Debate, 42(Suppl. 2), 37–47. [In Portuguese] https://doi.org/10.1590/0103-11042018S203

Fonseca, A. J. da, Ferreira, L. C. de L., & Neto, G. B. (2013). Cost-effectiveness of the vaccine against human papillomavirus in the Brazilian Amazon region. Revista da Associação Médica Brasileira, 59(5), 442–451. https://doi.org/10.1016/j.ramb.2013.03.004

Goldie, S. J., Kohli, M., Grima, D., Weinstein, M. C., Wright, T. C., Bosch, F. X., & Franco, E. (2004). Projected clinical benefits and cost-effectiveness of a human papillomavirus 16/18 vaccine. Journal of the National Cancer Institute, 96(8), 604–615. https://doi.org/10.1093/jnci/djh104

Guyottot, O., & Le Fur, E. (2022). A systematic literature review and bibliometric analysis of research on COVID-19 in strategy journals. Strategic Change, 32(2–3), 85–102. https://doi.org/10.1002/jsc.2538

Iraqui, A., Safia, A., Mahameed, M., Abd Elhadi, U., & Merchavy, S. (2025). Global prevalence and modifiers of human papillomavirus positivity in oral cavity cancer: A systematic review and meta-analysis of prevalence (1995–2024). Cancers, 17(17), 2870. https://doi.org/10.3390/cancers17172870

Islam, M. N., Islam, M. S., & Roy, P. B. (2025). A bibliometric technique for analyzing trends in public health research. Data Science and Informetrics, 4, 89–103. https://doi.org/10.1016/j.dsim.2025.01.010

Iwu-Jaja, C., Ndwandwe, D., Malinga, T., Mathebula, L., Mazingisa, A., & Wiysonge, C. S. (2025). Vaccine research trends in Africa from 2016 to mid-2024: A bibliometric analysis. Vaccines, 13(5), 509. https://doi.org/10.3390/vaccines13050509

Ji, L., Chen, M., & Yao, L. (2023). Strategies to eliminate cervical cancer in China. Frontiers in Oncology, 13, 1105468. https://doi.org/10.3389/fonc.2023.1105468

Jouya, S., Shahabinia, Z., Mazidimoradi, A., Allahqoli, L., Salehiniya, H., & Lee, D.-Y. (2026). Cervical cancer epidemiology: Global incidence, mortality, survival, risk factors, and equity in HPV screening and vaccination. Journal of Clinical Medicine, 15(3), 1079. https://doi.org/10.3390/jcm15031079

Kiendrébéogo, J. A., Sidibe, A. R. O., Compaoré, G. B., Nacanabo, R., Sory, O., Ouédraogo, I., Nawaz, S., Schuind, A. E., & Clark, A. (2023). Cost-effectiveness of human papillomavirus (HPV) vaccination in Burkina Faso: a modelling study. BMC Health Services Research, 23, 1338. https://doi.org/10.1186/s12913-023-10283-3

Kurosawa, M., Sekine, M., Yamaguchi, M., Kudo, R., Hanley, S. J. B., Hara, M., Adachi, S., Ueda, Y., Miyagi, E., Ikeda, S., Yagi, A., & Enomoto, T. (2022). Long-term effectiveness of HPV vaccination against HPV infection in young Japanese women: Real-world data. Cancer Science, 113(4), 1435–1440. https://doi.org/10.1111/cas.15282

Laprise, J. F., Chesson, H. W., Markowitz, L. E., Drolet, M., Martin, D., Bénard, É., & Brisson, M. (2020). Effectiveness and cost-effectiveness of human papillomavirus vaccination through age 45 years in the United States. Annals of Internal Medicine, 172(1), 22–29. https://doi.org/10.7326/M19-1182

Li, J., Li, R., Qin, R., Wang, H., Wang, D., & Zhou, L. (2025). Cost-effectiveness analysis of HPV vaccination for the prevention of oropharyngeal cancer in Chinese adolescent males. Frontiers in Public Health, 13, 1584956. https://doi.org/10.3389/fpubh.2025.1584956

Li, Y., Soh, K. L., Jing, X., Wei, L., Rajen Durai, R., & Soh, K. G. (2025). Bibliometric analysis of resilience in stroke from 2000 to 2024 using CiteSpace and VOSviewer. Frontiers in Psychology, 16, 1452249. https://doi.org/10.3389/fpsyg.2025.1452249

Lima, T. G. F. M. S., Coutinho, K. D., Batista, N. A. N., Galvão, R. E., Araújo, B. F., Martins, I. M. A., Alves, L. P. C. F., Romão, M. H., Lacerda, J. S., Oliveira, C. A. P., Dias, A. P., Cunha, P. S., Oliveira, A. C., Cordeiro, A. M. R., Gallego, A. M., Ramos, M. N. P., Oliveira, C. M. B. P., Campos, R. P., & Valentim, R. A. M. (2024). International scientific cooperation in public health: A performance measurement framework based on the "Syphilis No!" project in Brazil. Global Health Economics and Sustainability, 2(2), 3037. https://doi.org/10.36922/ghes.3037

Lu, W., Li, Y., Montayre, J., Li, M., Ho, K. Y., Li, J., & Yorke, J. (2025). A bibliometric analysis of healthcare intervention-related studies reporting patient and public involvement and engagement. Healthcare, 13(3), 305. https://doi.org/10.3390/healthcare13030305

Machado, F. V., Rech, C. M., Pinto, R. S., Romão, W. M., Matias, M. M. M., Freitas, G. C., Leles, F. A. G., & Kujawa, H. (2023). Participation in health in the Americas: Bibliometric mapping of production, impact, visibility and collaboration. Ciência & Saúde Coletiva, 28(2), 487–500. https://doi.org/10.1590/1413-81232023282.11412022EN

Meng, X., Yang, B., Yin, H., Chen, J., Ma, W., Xu, Z., & Shen, Y. (2025). Global burden and incidence trends in cancers associated with human papillomavirus infection: A population-based systematic study. Pathogens, 14(9), 880. https://doi.org/10.3390/pathogens14090880

Momenimovahed, Z., Mazidimoradi, A., Maroofi, P., Allahqoli, L., Salehiniya, H., & Alkatout, I. (2023). Global, regional and national burden, incidence, and mortality of cervical cancer. Cancer Reports, 6(3), e1756. https://doi.org/10.1002/cnr2.1756

Mongan, S. P., Byrnes, J., & Kim, H. (2025). The cost-effectiveness of the human papilloma virus vaccination in Asia Pacific countries: What lessons can Indonesia learn?—A systematic review. Vaccines, 13(6), 593. https://doi.org/10.3390/vaccines13060593

Moura, L. L., Codeço, C. T., & Luz, P. M. (2021). Human papillomavirus (HPV) vaccination coverage in Brazil: spatial and age cohort heterogeneity. Revista Brasileira de Epidemiologia, 24, e210001. https://doi.org/10.1590/1980-549720210001

Nandi, A., & Shet, A. (2020). Why vaccines matter: Understanding the broader health, economic, and child development benefits of routine vaccination. Human Vaccines & Immunotherapeutics, 16(8), 1900–1904. https://doi.org/10.1080/21645515.2019.1708669

Narasimhamurthy, M., & Kafle, S. U. (2022). Cervical cancer in Nepal: Current screening strategies and challenges. Frontiers in Public Health, 10, 980899. https://doi.org/10.3389/fpubh.2022.980899

Neumann, P. J., Sanders, G. D., Russell, L. B., Siegel, J. E., & Ganiats, T. G. (Ed.). (2017). Cost-effectiveness in health and medicine (2nd ed.). Oxford University Press.

Novaes, H. M. D., de Soárez, P. C., Silva, G. A., Ayres, A., Itria, A., Rama, C. H., Sartori, A. M. C., Clark, A. D., & Resch, S. (2015). Cost-effectiveness analysis of introducing universal human papillomavirus vaccination of girls aged 11 years into the national immunization program in Brazil. Vaccine, 33(Suppl. 1), A135–A142. https://doi.org/10.1016/j.vaccine.2014.12.031

Pan American Health Organization. (n.d.). Cervical cancer. PAHO/WHO. Available from: https://www.paho.org/en/ topics/cervical-cancer (Last accessed on June 11, 2026).

Parodi, J. F., Runzer-Colmenares, F., Cano-Gutiérrez, C., Dinamarca-Montecinos, J. L., Bendía-Gomez de La Torre, P., Villas Boas, P. F., Flores-Cohaila, J., Urrunaga-Pastor, D., & Gutiérrez-Robledo, L. M. (2025). Respiratory vaccines in older adults: A bibliometric analysis and future research agenda. Vaccines, 13(3), 240. https://doi.org/10.3390/vaccines13030240

Pilone, V., Di Santo, N., & Sisto, R. (2023). Factors affecting food waste: A bibliometric review on the household behaviors. PLoS ONE, 18(7), e0289323. https://doi.org/10.1371/journal.pone.0289323

Rodrigues, I. O., Duarte, I., Costa, C. G., Pimentel, A. L., Chaves, S., Gomes, A. P., Santos, L., Santos, J. I., Moreira, A. C., Lobão, A., Nazaré, I., & Santos, P. (2024). Knowledge about cervical cancer in young Portuguese women: A cross-sectional study. Frontiers in Public Health, 12, 1357606. https://doi.org/10.3389/fpubh.2024.1357606

Rosettie, K. L., Joffe, J. N., Sparks, G. W., Aravkin, A., Chen, S., Compton, K., Ewald, S. B., Mathew, E. B., Michael, D., Pedroza Velandia, P., Miller-Petrie, M. B., Stafford, L., Zheng, P., Weaver, M. R., & Murray, C. J. L. (2021). Cost-effectiveness of HPV vaccination in 195 countries: A meta-regression analysis. PLOS ONE, 16(12), e0260808. https://doi.org/10.1371/journal.pone.0260808

Şahin, Ç. E., & Karabey, S. (2025). Cost effectiveness of female HPV vaccines for routine childhood immunisation schedule in Türkiye. BMC Public Health, 25(1), 3561. https://doi.org/10.1186/s12889-025-24878-4

Santos, A. C. S., Silva, N. N. T., Silva, I. D. C. G., Carneiro, M., Coura-Vital, W., & Lima, A. A. (2025). Effectiveness of HPV vaccination in reducing infection among young Brazilian women. BMC Infectious Diseases, 25, 88. https://doi.org/10.1186/s12879-024-10284-5

Santos, M. O., Lima, F. C. S., Martins, L. F. L., Oliveira, J. F. P., Almeida, L. M., & Cancela, M. C. (2023). Estimativa de incidência de câncer no Brasil, 2023–2025 [Estimated cancer incidence in Brazil, 2023–2025]. Revista Brasileira de Cancerologia, 69(1), e-213700. [In Portuguese] https://doi.org/10.32635/2176-9745.rbc.2023v69n1.3700

Santos, W. M., Santos, D. M., & Fernandes, M. S. (2023). HPV immunization in Brazil and proposals to increase adherence to vaccination campaigns. Revista de Saúde Pública, 57, 79. https://doi.org/10.11606/s1518-8787.2023057005410

Setiawan, D., Nurulita, N. A., Khoirunnisa, S. M., & Postma, M. J. (2024). The clinical effectiveness of one-dose vaccination with an HPV vaccine: A meta-analysis of 902,368 vaccinated women. PLoS ONE, 19(1), e0290808. https://doi.org/10.1371/journal.pone.0290808

Schiffman, M., Doorbar, J., Wentzensen, N., de Sanjosé, S., Fakhry, C., Monk, B. J., Stanley, M. A., & Franceschi, S. (2016). Carcinogenic human papillomavirus infection. Nature Reviews Disease Primers, 2, 16086. https://doi.org/10.1038/nrdp.2016.86

Silva, G. O., & Silva Elias, F. T. (2017). Parcerias para o desenvolvimento produtivo: Um estudo de avaliabilidade [Productive development partnerships: An evaluability study]. Comunicação em Ciências da Saúde, 28(2). [In Portuguese] Available from: https://revistaccs.espdf.fepecs. edu.br/index.php/comunicacaoemcienciasdasaude/en/ article/view/201 (accessed on April 16, 2025).

Singh, D., Vignat, J., Lorenzoni, V., Eslahi, M., Ginsburg, O., Lauby-Secretan, B., Arbyn, M., Basu, P., Bray, F., & Vaccarella, S. (2023). Global estimates of incidence and mortality of cervical cancer in 2020: a baseline analysis of the WHO Global Cervical Cancer Elimination Initiative. The Lancet Global Health, 11(2), e197–e206. https://doi.org/10.1016/S2214-109X(22)00501-0

Tejada, R. A., Malagón, T., & Franco, E. L. (2022). Cost-effectiveness of human papillomavirus vaccination in girls living in Latin American countries: A systematic review and meta-analysis. Vaccine, 40(19), 2667–2678. https://doi.org/10.1016/j.vaccine.2022.03.046

Teixeira, J. C., Vale, D. B., Bragança, J. F., Campos, C. S., Discacciati, M. G., & Zeferino, L. C. (2020). Cervical cancer screening program based on primary DNA-HPV testing in a Brazilian city: A cost-effectiveness study protocol. BMC Public Health, 20(1), 576. https://doi.org/10.1186/s12889-020-08688-4

Tran, J., Hathaway, C. L., Broshkevitch, C. J., Palanee-Phillips, T., Barnabas, R. V., Rao, D. W., & Sharma, M. (2024). Cost-effectiveness of single-visit cervical cancer screening in KwaZulu-Natal, South Africa: A model-based analysis accounting for the HIV epidemic. Frontiers in Oncology, 14, 1382599. https://doi.org/10.3389/fonc.2024.1382599

Triantafyllopoulos, L., Paxinou, E., Feretzakis, G., Kalles, D., & Verykios, V. S. (2024). Mapping how artificial intelligence blends with healthcare: Insights from a bibliometric analysis. Future Internet, 16(7), 221. https://doi.org/10.3390/fi16070221

Van Eck, N. J., & Waltman, L. (2010). Software survey: VOSviewer, a computer program for bibliometric mapping. Scientometrics, 84(2), 523–538. https://doi.org/10.1007/s11192-009-0146-3

Varrichio, P. (2017). As parcerias para o desenvolvimentoprodutivo da saúde [Partnerships for productive development in health]. In A. T. Rauen (Ed.), Políticas de inovação pelo lado da demanda no Brasil (Cap. 5, pp. 179– 234). Instituto de Pesquisa Econômica Aplicada (IPEA). [In Portuguese] Available from: https://repositorio.ipea.gov.br/ items/8e6a2728-447d-4c1d-bb7b-0008d0597e1e (accessed on February 10, 2025).

Vittori, A., Cascella, M., Leonardi, M., Monaco, F., Nocerino, D., Cuomo, A., Ottaiano, A., Perri, F., Mascilini, I., Francia, E., Petrucci, E., Marinangeli, F., & Picardo, S. G. (2022). VOSviewer-based bibliometric network analysis for evaluating research on juvenile primary fibromyalgia syndrome (JPFS). Children, 9(5), 637. https://doi.org/10.3390/children9050637

World Health Organization. (2020). Global strategy to accelerate the elimination of cervical cancer as a public health problem. Available from: https://iris.who.int/handle/10665/336583 (accessed on April 23, 2026).

World Health Organization. (2024). Cervical cancer elimination day of action 2024. Available from: https://www.who.int/ campaigns/cervical-cancer-elimination-day-of-action/2024 (accessed on March 15, 2025).

Wu, S., Jiao, J., Yue, X., & Wang, Y. (2024). Cervical cancer incidence, mortality, and burden in China: A time-trend analysis and comparison with England and India based on the Global Burden of Disease Study 2019. Frontiers in Public Health, 12, 1358433. https://doi.org/10.3389/fpubh.2024.1358433

Zhao, Z., Hu, B., Xu, K., Jiang, Y., Xu, X., & Liu, Y. (2024). A quantitative analysis of artificial intelligence research in cervical cancer: A bibliometric approach utilizing CiteSpace and VOSviewer. Frontiers in Oncology, 14, 1431142. https://doi.org/10.3389/fonc.2024.1431142

Zeng, D., Wang, J., Xiao, B., Zhang, H., & Ma, X. (2023). A bibliometric visualization analysis on vaccine development of Coronavirus Disease 2019 (COVID-19). Vaccines, 11(2), 295. https://doi.org/10.3390/vaccines11020295