
Bioprinting has emerged as a transformative approach in musculoskeletal tissue engineering, offering precise control over scaffold architecture, cell distribution, and bioactive factor delivery. This Special Issue focuses on innovative strategies to enhance bone and tendon-to-bone interface integration, addressing key challenges in osseointegration, tendon attachment, and functional musculoskeletal repair. Contributions are invited that explore novel bioprinting techniques, biomaterial design, and hybrid biofabrication approaches, including scaffold optimization, gradient or multiphasic constructs, and incorporation of cells or signaling cues to promote tissue regeneration. Translational studies, in vitro and in vivo evaluations, and computational modeling supporting interface functionality are encouraged. This collection aims to highlight cutting-edge advances that bridge basic research and clinical applications, providing insights into the design principles and biological mechanisms underlying successful musculoskeletal integration via bioprinting.


