AccScience Publishing / IJB / Online First / DOI: 10.36922/ijb.8411
REVIEW
Early Access

3D Bioprinting for Tendon-Bone Interface Regeneration

Yifan Wang1 Cong Chen1 Chuyue Zhang1 Junyao Cheng1 Bochen An1 Ning Zhang2* Jianheng Liu1* Zheng Wang1*
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1 Department of Orthopedics, Chinese PLA General Hospital, Beijing 100853, China
2 Department of Orthopedics, The Second Hospital of Shandong University, Jinan 250033, China
Submitted: 5 January 2025 | Accepted: 22 January 2025 | Published: 23 January 2025
© 2025 by the Author(s). This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution 4.0 International License ( https://creativecommons.org/licenses/by/4.0/ )
Abstract

With the rapid advancement of 3D bioprinting technology, its applications in tissue engineering and regenerative medicine have garnered increasing attention. Tendon-bone healing is a complex biological process which is why injuries to the tendon-bone interface are difficult to heal. Fortunately, 3D bioprinting provides numerous innovative solutions nowadays. Herein, we summarize the current state of 3D bioprinting technology in tendon-bone healing, exploring the latest developments in biomaterials, printing technologies, cell carriers, and preclinical research. In conclusion, the article discusses the current challenges faced in this field and outlines future research directions with careful consideration, providing valuable insights for ongoing investigations.

Funding
This work was supported by the National Natural Science Foundation of China (82172392‬).
Conflict of interest
3D bioprinting, Tendon-bone healing, Tissue engineering, Biomaterials, Cell carriers
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International Journal of Bioprinting, Electronic ISSN: 2424-8002 Print ISSN: 2424-7723, Published by AccScience Publishing