AccScience Publishing / IJB / Online First / DOI: 10.36922/ijb.4899
RESEARCH ARTICLE
Early Access

Design, fabrication and evaluation of a novel 3D-printed temporomandibular joint prosthesis enhanced with elastic layers

Junqi Jiang1 Zhiwei Jiao2 Bingxue Cheng3 Jianmin Han4 Xiangliang Xu1* Chuanbin Guo1*
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1 Department of Oral and Maxillofacial Surgery, National Center of Stomatology and National Clinical Research Center for Oral Diseases and National Engineering Research Center of Oral Biomaterials and Digital Medical Devices and Beijing Key Laboratory of Digital Stomatology and Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health and NMPA Key Laboratory for Dental Materials, Peking University School and Hospital of Stomatology, Beijing, China
2 College of Mechanical and Electrical Engineering, Beijing University of Chemical Technology, Beijing, China
3 State Key Laboratory of Tribology in Advanced Equipment, Tsinghua University, Beijing, China
4 Tianjin Medical University School and Hospital of Stomatology&Tianjin Key Laboratory of Oral Soft and Hard Tissues Restoration and Regeneration Department, Tianjin, China
Submitted: 20 September 2024 | Accepted: 20 November 2024 | Published: 20 November 2024
© 2024 by the Author(s). This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution 4.0 International License ( https://creativecommons.org/licenses/by/4.0/ )
Abstract

Artificial temporomandibular joint (TMJ) replacement is a common intervention for the treatment of advanced temporomandibular joint diseases and ankylosis. The present study addresses the insufficient elasticity of existing artificial TMJs through the development of a composite material by incorporating high-density polyethylene into ultra-high-molecular-weight polyethylene. This was processed using fused deposition modeling 3D-printing technology to produce porous elastic layers with an elastic modulus similar to that of joint discs. An artificial TMJ prosthesis with physiological elasticity was successfully fabricated, applied to the surface of porous Ti-6Al-4V alloy, and validated through mechanical experiments. The results demonstrated that the elastic modulus of the synthetic cartilage exhibits a negative correlation with the number of staggered layers, while no significant relationship was observed between the elastic modulus and the layering cross-angle. The elastic modulus of the cartilage was measured to be 127.5 ± 16.1 MPa, while the maximum compressive strength was found to be 8.0 ± 1.3 MPa. Optimal performance was observed for a staggered layer count of five and a cross-angle of 90°. The bonding strength to the metal mandibular prosthesis was measured to be 2.62 ± 0.98 MPa, and the surface roughness was determined to be 1.6 µm. An elastic artificial temporomandibular joint process prosthesis in this study was successfully designed, fabricated and validated through in vitro experiments, offering valuable insights for future advancements in artificial TMJ design.

Keywords
Artificial temporomandibular joint replacement
3D printing
Elasticity
Porous elastic layers
Ultra-high-molecular-weight polyethylene
Ti-6Al-4V alloy
Funding
This work was supported by grants from Beijing Municipal Science & Technology Commission (Z201100005520055), Clinical Research Foundation of Peking University School and Hospital of Stomatology (PKUSS-2023CRF205).
Conflict of interest
The authors declare they have no competing interests.
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International Journal of Bioprinting, Electronic ISSN: 2424-8002 Print ISSN: 2424-7723, Published by AccScience Publishing