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REVIEW

Advancements in bioprinting for the treatment of hearing loss: A review

Yanyan Ding1 ,  Qin Liu1 ,  Jinwu Chen2 ,  Hua Cai1 ,  Yue Qiu1 ,  Ming Li1 ,  Le Xie1 ,  Zhenyu Zhao3* ,  Ying Xiao1*
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1 Department of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
2 Department of Trauma Surgery, CR & WISCO General Hospital, School of Medicine, Wuhan University of Science and Technology, Wuhan, Hubei, China
3 Department of Electrical and Computer Engineering, Faculty of Engineering, National University of Singapore, Singapore
IJB 2024, 10(4), 3497 https://doi.org/10.36922/ijb.3497
Submitted: 24 April 2024 | Accepted: 23 May 2024 | Published: 4 July 2024
© 2024 by the Author(s).. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution 4.0 International License ( https://creativecommons.org/licenses/by/4.0/ )
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Abstract

Hearing loss is a prevalent worldwide health concern, characterized by structural or functional abnormalities in any part of the ear resulting in varying degrees of auditory dysfunction. Despite significant progress, there exists a notable deficiency in reliable and safe therapeutic interventions for addressing hearing loss. Bioprinting, a novel method in the realm of advanced tissue engineering, exhibits significant potential in addressing ear-related ailments. This technology provides a wide range of repair mechanisms specifically designed to address the distinct anatomical and functional requirements of the outer ear, middle ear, and inner ear, potentially leading to advancements in the treatment of different types of hearing loss. Furthermore, bioprinting holds promise for producing tissue constructs that are both anatomically accurate and functionally suitable, potentially revolutionizing the current treatment landscape. Nevertheless, thorough research and development efforts are necessary to fully harness the capabilities of bioprinting and establish it as a widely accepted treatment option for hearing loss.

Keywords
Bioprinting; Hearing Loss
Regenerative medicine
Funding
This work was supported by grants from the National Natural Science Foundation of China (Nos. 82201300, 82201301, 82301324), the Joint Fund of Hubei Provincial Health and Family Planning Commission (WJ2018H0110), the Science Foundation of Union Hospital (2021XHYN113), and the National University of Singapore.
Conflict of interest
The authors declare no conflicts of interest.
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International Journal of Bioprinting, Electronic ISSN: 2424-8002 Print ISSN: 2424-7723, Published by AccScience Publishing
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