AccScience Publishing / IJB / Volume 10 / Issue 2 / DOI: 10.36922/ijb.1752
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REVIEW

Recent developments and challenges of 3D bioprinting technologies

Ximin Yuan1,2 Zhenjia Wang1,2 Lixin Che3 Xushuai Lv1,2 Jie Xu1,2* Debin Shan1,2 Bin Guo1,2*
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1 State Key Laboratory of Advanced Welding and Joining, Harbin Institute of Technology, Harbin, Heilongjiang, China
2 National Innovation Center for Advanced Medical Devices, Shenzhen, Guangdong, China
3 Dalian Jiang Xiaolan Dental Clinic Co., Ltd, Dalian, Liaoning, China
IJB 2024, 10(2), 1752 https://doi.org/10.36922/ijb.1752
Submitted: 3 September 2023 | Accepted: 30 October 2023 | Published: 27 January 2024
(This article belongs to the Special Issue Advances in bioprinting technologies)
© 2024 by the Author(s). This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution 4.0 International License ( https://creativecommons.org/licenses/by/4.0/ )
Abstract

Three-dimensional (3D) bioprinting technologies play significant roles in various facets of the medical field, such as bioengineering, tissue repair, scaffolds, biomedical devices, and drug. As a versatile manufacturing technology, 3D bioprinting is able to overcome the constraints of other conventional methods and shows potential for future advancements in the field of biology. Nevertheless, the existing 3D bioprinting technologies still grapple with significant challenges in materials, equipment, and applications. Therefore, it is essential to select appropriate bioprinting method in alignment with the required application. In this review, we aim to cover the development, classification, and application of 3D bioprinting, with a particular emphasis on the fundamental printing principles. Additionally, we discuss the potential of 3D bioprinting in terms of materialization, structuralization, and functionalization, highlighting its prospective applications. We firmly believe that 3D printing technology will witness widespread adoption in the future, as it has the potential to address the limitations associated with multi-size, multi-material, multi-cell, and high-precision bioprinting. 

Keywords
Tissue engineering
Scaffolds
Biomedical devices
Drug delivery
Funding
This work was supported by Heilongjiang Province Key Research and Development Program Under Grant (2022XJ03C07).
Conflict of interest
The authors declare no conflicts of interest.
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International Journal of Bioprinting, Electronic ISSN: 2424-8002 Print ISSN: 2424-7723, Published by AccScience Publishing