AccScience Publishing / IJB / Volume 10 / Issue 1 / DOI: 10.36922/ijb.0119
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RESEARCH ARTICLE

In-plane measurements and computational fluid dynamics prediction of permeability for biocompatible NiTi gyroid scaffolds fabricated via laser powder bed fusion

Stanislav V. Chernyshikhin1* Biltu Mahato1 Aleksei V. Shiverskii1 Ivan A. Pelevin2 Oleg N. Dubinin1,3 Vladimir Yu. Egorov2 Sergey G. Abaimov1 Igor V. Shishkovsky1
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1 Skolkovo Institute of Science and Technology, 121205 Moscow, Russia
2 Catalysis Lab, National University of Science and Technology MISIS, 119049 Moscow, Russia
3 World-Class Research Center, Saint Petersburg State Marine Technical University, 190121 Saint Petersburg, Russia
IJB 2024, 10(1), 0119 https://doi.org/10.36922/ijb.0119
Submitted: 7 April 2023 | Accepted: 30 May 2023 | Published: 18 August 2023
© 2023 by the Author(s). This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution 4.0 International License ( https://creativecommons.org/licenses/by/4.0/ )
Abstract

Laser powder bed fusion (LPBF) is considered a promising technology for manufacturing porous, biomimetic, and patient-specific scaffolds for bone repair. Scaffold permeability is one of the key factors to be considered for acquiring the required mass-transport properties in bone tissue engineering. This study aims to reveal the relationship between the design parameters of gyroid-based porous structure and scaffold permeability. A set of gyroid samples was manufactured from intermetallic NiTi alloy. Nine configurations of porous structures were obtained by varying the main design parameters, namely wall thickness and unit cell size. The in-plane method was employed to measure the permeability coefficient for the gyroid structures. Computational fluid dynamics simulations of the porous structures were performed to predict the targeted properties in an implant at the design stage before LPBF manufacturing. The results of the simulations were validated with the obtained experimental results. Geometrical accuracy and surface morphology of the as-built samples were investigated with various techniques. Biocompatibility assessment of the gyroid scaffolds was performed with human cell culture experiments. 

Keywords
Biomimetic implant
Laser powder bed fusion
Nickel–titanium
Gyroid structures
Permeability
Mass-transport properties
Funding
The reported study was funded by Russian Foundation for Basic Research (RFBR), project number 20-51-56011.
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Conflict of interest
The authors declare no conflict of interest.
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International Journal of Bioprinting, Electronic ISSN: 2424-8002 Print ISSN: 2424-7723, Published by AccScience Publishing