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Editorial Board Please note that the order in which the Editors appear on this page is alphabetical.
Tao Jiang
Beijing Neurosurgical Institute, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
Interests: Glioma; Molecular Classification; Individualized Comprehensive Therapy; Molecular Targeted Therapy
Yan Yao
Fuwai Hospital, Chinese Academy of Medical Sciences, Beijing, China
Interests: Cardiovascular Disease; Heart Rhythm; Syncope; Sudden Cardiac Death; Autonomous Nerve
Associate Editors
Liqun Jiao
Department of Interventional Radiology, Xuanwu Hospital, Capital Medical University, Beijing, China
Interests: Cerebrovascular Disease; Carotid Stenosis
Editorial Board Members
M Chadi Alraies
Wayne State University and Detroit Medical Center, Detroit, Michigan, United States
Interests: Interventional Cardiology; High Risk Intervention; Coronary Intervention; Valvular Heart Disease; Endovascular Procedures; Vascular Access; Mechanical Circulatory Support; Ischemia; Acute Coronary Syndrome; Acute Myocardial Infarction
Fabio Angeli
1. Department of Medicine and Technological Innovation, University of Insubria, 21100 Varese, Italy 2. Department of Medicine and Cardiopulmonary Rehabilitation, Maugeri Care and Research Institutes, IRCCS Tradate, 21049 Tradate, Italy
Interests: Cardiovascular risk assessment in patients with hypertension; Diabetes; Heart failure and coronary artery disease; Evaluation of cardiovascular treatment; Diagnosis and treatment of acute myocardial infarction
Emil Marian Arbanasi
1 Department of Vascular Surgery, Mureș County Emergency Hospital, Targu Mures, Romania and George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, Romania; 2 Regenerative Medicine Laboratory, Center for Advanced Medical and Pharmaceutical Research, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, Romania; 3 Experimental Medicine and Medical Imaging Research Center, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, Romania.
Interests: Vascular surgery; Arteriovenous fistula; Abdominal aortic aneurysms; Carotid disease; Peripheral arterial disease; Bioengineering; Biomechanical properties; Arterial reconstruction; By-pass; Angioplasty
Dmitriy Atochin
Cardiovascular Research Center, Mass General Research Institute, Harvard Medical School, Boston, MA, United State
Interests: Brain Ischemia; C-Reactive Protein; Cerebrovascular Circulation; Genetic Modelling; Hyperbaric Oxygenation; In Vitro Vascular Reactivity; Infarction Middle Cerebral Artery; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type Ii; Nitric Oxide Synthase Type Iii; Reperfusion Injury
Sergio Berti
Gabriele Monasterio Foundation, Pisa, Italy
Interests: cardiology, radiology, nuclear medicine
Natan Bornstein
Brain Division at Shaare-Zedek Medical Center, Jerusalem, Israel
Interests: Epidemiology of stroke; Stroke prevention; Vascular dementia; Inflammation and stroke; Neurosonology
Simone Calcagno
Department of Cardiology, San Paolo Hospital, Civitavecchia, Rome, Italy
Interests: Cardiology, Interventional Cardiology, Ischemic Coronary Disease, Structural Heart Disease and Coronary Revascularization, Heart Failure
Yong Cao
Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
Interests: Neurosurgery; Cerebrovascular Diseases; Cerebrovascular Malformation; Intracranial Aneurysm; Genetics in Cerebrovascular Diseases; Individualized Therapy in Cerebrovascular Diseases
Feng-Chi Chang
Department of Radiology, Taipei Veterans General Hospital, Taipei, Taiwan region; School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan region
Interests: Neuroradiology
Jun Chen
Department of Bioengineering at the University of California, Los Angeles, USA
Interests: nanotechnology, bioelectronics for energy, sensing, therapeutic applications in the form of smart textiles, wearables, body area networks
Chunguang Chen, MD, FACC
Deborah Heart and Lung Center, Thomas Jefferson University Sidney Kimmel Medical College; Cooperman Barnabas Medical Center, RWJ Barnabas Healthcare System, New Jersey School of Medicine, Rutger University, New Jersey, United States
Interests: Stress Echocardiography; Transesophageal Echocardiography; Structural heart imaging; Cardiovascular Disease; Cardiovascular Computed Tomography (CT)
Special Issue and Collections in AccScience journals
Antonio Curnis
Division of Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University and Civil Hospital of Brescia, Brescia, Italy
Interests: Atrial Fibrillation; Heart Failure; Pacemakers; Cardiology; Cardiomyopathies; Echocardiography; Chronic Heart Failure; Electrocardiography; Cardiovascular
Gianni Dall'Ara
Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy
Interests: Coronary artery disease; Percutaneous revascularization; Structural heart disease; Right heart cath; Antiplatelet and anticoagulant therapy
Sam El-Osta
Baker Heart and Diabetes Institute, Melbourne, Australia
Interests: Epigenetic Differences Associated with Cardiovascular disease; Clinical and Molecular; Epigenetics; Chromatin; Diabetes; Histones; Transcriptional Regulation; Computational Epigenomics; Epilepsy; Neurological Disorders; Metabolic Disease; DOHAD; POTS; Orthostatic Intolerance
Francisco Epelde
Internal Medicine Department, Hospital de Sabadell, University Autonoma of Barcelona, Parc Tauli, 08208 Barcelona, Spain
Interests: Heart failure; Atriall fibrillation; Ischemic cardiopathy; Hospital administration
Pompilio Faggiano
Fondazione Poliambulanza, Cardiothoracic Department Unit, Brescia, Italy
Interests: Preventive cardiology; Lipidology; Valvular heart disease; Patent foramen ovale; Atherosclerosis; Echocardiography; Non-invasive imaging; Heart failure; Atrial fibrillation
Yinghong Feng
Uniformed Services University of the Health Sciences, Bethesda, United States
Interests: Receptor Structure-Function & Signaling; Epigenome Editing & Transcription Regulation; Translational Research in Neurodegenerative Diseases; Mood Disorder; Cancer; Diabetes; Cardiovascular Diseases
Mauro Feola
Cardiology Division Ospedale Regina Montis Regalis, Strada del Rocchetto 99, 12084 Mondovi, Italy
Interests: clinical cardiology; heart failure; cardiovascular imaging; echocardiography; cardiac magnetic resonance; nuclear cardiology; hemodynamics
Alfio Ferlito
International Head and Neck Scientific Group, Padua, Italy
Interests: head and neck surgery; oncology and cancer research
László Gellér
Heart and Vascular Center, Semmelweis University, Budapest, Hungary
Interests: Clinical and experimental electrophysiology; Farapulse - Pulsed Field Ablation; His Bundle Pacing; MitraClip; Heart Failure; Atrial Fibrillation; Cardiomyopathies; Chronic Heart Failure; Interventional Cardiology; Myocardial Infarction; Acute Myocardial Infarction; Electrocardiography; Clinical Cardiology
Nelli Giribabu
Physiology Department, University of Malaya, Kuala Lumpur, Malaysia
Interests: Cardiovascular; Neurology; Male and Female Reproductive Physiology; Fertility; Diabetes and Their Complications; Natural Products Research
Jun Guo
Department of Cardiology, The First Affiliated Hospital of Jinan University, Guangzhou, China
Interests: Hypertension; Heart failure, Arrhythmia; Coronary Heart Disease
Fuyou Guo
Department of Neurosurgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China
Interests: Cerebellopontine Angle; Clinical Feature; Teratoma
Qunying Guo
The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China
Interests: Chronic kidney disease; Peritoneal dialysis; Cardiovascular; Myocardial
Teruhiko Imamura
Second Department of Internal Medicine, University of Toyama, Toyama 9300194, Japan
Interests: Heart failure; Heart transplantation; Cardiology; Cardiothoracic surgery
Chunjie Jiang
Baylor Medical University, Houston, Texas, United States
Interests: Bioinformatics; Transcriptional Regulation; Metabolism; Circadian; Cancer Biology
Dingsheng Jiang
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
Interests: Cardiac Hypertrophy; Aortic Dissection; Heart Failure; Histone Methylation; Ferroptosis; Vascular Medicine
Weina Jin
China National Clinical Research Center for Neurological Diseases; Beijing Tiantan Hospital of Capital Medical University, Beijing, China
Interests: Neuroimmunology; Immunology in Stroke; Biomarker Development in Neurological Diseases
Ulf Dietrich Kahlert
Molecular and Experimental Surgery, House 65, University Medicine Magdeburg, Magdeburg, Germany
Interests: Cancer; Stem Cells; Cell Metabolism; Drug Development; Nanomedicine; Research Integrety
Chandrasekaran Kaliaperumal
Royal Infirmary of EdinburghThis link is disabled., Edinburgh, United Kingdom
Interests: Brain and spine tumours, Spinal degenerative disease, Trigeminal Neuralgia, Hydrocephalus, Chiari Malformation, Complex spinal dysraphisms, Craniofacial abnormalities (Craniosynostosis), Traumatic Brain & spinal injury
Chunsheng Kang
Tianjin Medical University General Hospital, Tianjin Neurological Institute, Tianjin, China
Interests: Cancer; Brain Drug Delivery; Stroke
Srikanth Karnati
Julius Maximilians University, Wuerzburg, Germany
Interests: Lipid Metabolism; Metabolism; Antioxidants; Immunohistochemistry; Hypertension; Lung Diseases; Antioxidant Activity; Immunofluorescence; Western Blot; Cell Culture
Anton Kiselev
National Medical Research Center for Therapy and Preventive Medicine, Moscow, Russia
Interests: Hypertension; Echocardiography; Atherosclerosis; Heart Failure; Atrial Fibrillation; Clinical Cardiology; Acute Coronary Syndrome; Arterial Hypertension
Vinay Kumar
Heart and Vascular Institute, Pennsylvania State University Hershey Medical Center, Hershey, PA-17033, USA
Interests: cardiovascular diseases; immunology; cell biology and physiology; molecular biology; heart failure; myocardial infarction
Giuseppe Lanza
University of Catania, Italy
Interests: Cognitive Disorders; COVID-19; Geriatrics; Neurology; Neuroscience; Psychiatry & Psychology; Rehabilitation; Translational Medicine
Zhe Kang Law
Department of Medicine, National University of Malaysia, Kuala Lumpur, Malaysia
Interests: Intracerebral Haemorrhage; Neurological Diseases; Clinical Neurology; EEG; Neuroimaging; Neurodegenerative Diseases; Neurophysiology; Stroke
Djamel Lebeche
Department of Physiology, and Neuroscience Institute, College of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee, United States
Interests: Pathobiology, Mechanisms and Therapies of Diabetic Cardiomyopathy; Functional Molecular Genomics and Cardiometabolic Disorders; Calcium Signaling; Myocardial Fibrosis; Genetic Instability; Heart Failure; Investigational Drug Discovery for Heart Failure and Diabetes and ER Stress Complications
Andrew Lee
College of Medicine and Public Health, Flinders University, Adelaide, Australia
Interests: Stroke Medicine; Retino-Vascular Disorders, Amyloid Angiopathy; Acute Reperfusion Therapies in Acute Stroke
Shujuan Li
Fuwai Hospital, Chinese Academy of Medical Sciences, Beijing, China
Interests: Stroke; Brain Protection; Neurocardiology
Tong Liu
Department of Cardiology, Tianjin Institute of Cardiology, Second Hospital of Tianjin Medical University, Tianjin, China
Interests: Atrial Fibrillation; Electrocardiography; Cardiomyopathies; Cardiology; Pacemakers; Cardiovascular Medicine; Heart Failure; Echocardiography; Clinical Cardiology; Cardiovascular
Xingpeng Liu
Department of Cardiology, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China
Interests: Atrial fibrillation ablation; electrocardiography
Brandon Lucke-Wold
Department of Neurosurgery, University of Florida, Gainesville, FL, USA
Interests: neurosurgery; neuroscience; subarachnoid hemorrhage; traumatic brain injury
Michael Maes
Chulalongkorn University, Bangkok, Thailand
Interests: Major depression; Cytokines; Tryptophan; Chronic fatigue syndrome; Redox signaling
Saurav Mallik
Department of Pharmacology and Toxicology, The University of Arizona, USA
Interests: Data mining, computational biology, bioinformatics, Bio-statistics, machine learning
Special Issue and Collections in AccScience journals
Giuseppe Mancia
Department of Clinical Medicine and Prevention, University of Milano-Bicocca, Milan, Italy
Interests: Pathophysiology; Clinical Pharmacology and Therapy of Hypertension; Congestive Heart Failure; Cardiovascular Diseases; Cardiovascular Outcome
Jose Carlos Pachon Mateos
Cardiologia pela, Universidade de São Paulo, São Paulo, Brazil
Interests: Arrhythmia; Electrophysiology; Pacemakers; Resynchronizers; Cardiac Defibrillators
Víctor Tapias Molina
Excellence Unit of the Institute of Genetics and Molecular Biology (IBGM), University of Valladolid and CSIC, Valladolid, Spain; Dept. Biochemistry and Molecular Biology and Physiology, University of Valladolid Medical School, Valladolid, Spain
Interests: Parkinson’s Disease, Alzheimer’s Disease, Gene Therapy, Mitochondria, Oxidative Stress
Andreia Morais
Neurovascular Research Unit, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, United States
Interests: Stroke Therapy; Migraine Disorders; Migraine with Aura; Cortical Spreading Depression; Spreading Depression (SD); Spreading Depolarization (SD); Electrocorticogram (ECoG); Vagus Nerve stimulation/VNS; Aging Neuroscience
Federica Moscucci
Sapienza University of Rome, Rome, Italy
Interests: Geriatria; Cardiologia
Mohamad Navab
Division of Cardiology, David Geffen School of Medicine at University of California, Los Angeles, California, United States
Interests: HDL; Mimetic Peptides; Atherosclerosis, Lipids; Artery Wall Metabolism; Small Intestine; Systemic Inflammation; Cardiovascular Function; Gut Microbiota in Dyslipidemia
Patricia K. Nguyen
Stanford Cardiovascular Institute, Stanford University School of Medicine, California, United States
Interests: Cardiology; Immune Checkpoint Inhibitors; Cardiotoxicity; Cardio-oncology; Cardiology; Atherosclerosis; Cardio-immunology; Molecular Imaging
Uwe Nixdorff
EPC GmbH -European Prevention Center;c/o Medical Center Düsseldorf (Grand Arc), Duesseldorf, Germany
Interests: cardiovascular imaging; echocardiography together with tissue Doppler / strain rate; stress echocardiography including myocardial reperfusion / hibernation beside stunning; cardiac multidetector computed tomography (MDCT with CACS and CCTA),cardiac magnetic resonance tomography (CMR); subclinical imaging, cardiovascular risk stratification and preventive cardiology including prinipals of personalized medicine
Mário Martins Oliveira
Cardiology Service, Hospital Santa Marta, Habilitation of Physiology, Medicine of Lisbon University, Lisbon, Portugal
Interests: Interventional Cardiology; Heart Failure; Atrial Fibrillation; Arrhythmias; Cardiac Resynchronization Therapy; Tachycardia; Ventricular Fibrillation
Aynur Ozge
Department of Neurology, School of Medicine, Mersin University, Mersin, Turkey
Interests: Headache; Migraine; Dementia; Elderly; Cognitive impairment
Pasquale Parisi
Faculty of Medicine & Psychology, Sapienza University, Rome, Italy
Interests: Pediatrics; Pediatric Neurology; Epilepsy; Headache; Migraine.
Valeria Pergola
University of Padua, Padua, Italy
Interests: Cardiology
Emilio Perucca
The University of Melbourne, Melbourne, Australia
Interests: clinical pharmacology, AEDs, drug treatment, seizure disorders, clinical trial methodology, epilepsy
Ivo Petrov
Clinic of Cardiology and Angiology, Acibadem City Clinic Cardiovascular Center University Hospital, Sofia, Bulgaria
Interests: Endovascular treatment of aortic dissection; Endovascular treatment of thoracic, Abdominal and thoracoabdominal aneurysms; Procedural and clinical results of renal denervation; Carotid artery stenting (including radial approach for CAS, cognitive dysfunction of patients with "string sign" carotid stenosis and level of correction after endovascular recanalization); Coronary stenting in complex scenarios (bifurcations, calcium containing lesions); TAVI (minimalistic approach for TAVI, bail-out procedures in cases of PVL); TEER (MitraClip) for patients with mitral regurgitation and prohibitive surgical risk; Catheter-based treatment of intermediate and high-risk patients with pulmonary embolism; Artificial intelligence facilitated thermography to detect carotid and peripheral vascular disease
Simon Rabkin
Division of Cardiology, University of British Columbia, Vancouver, Canada
Interests: Translational medicine
Redi Rahmani
University of Rochester, Rochester, New York, United States
Interests: Neurosurgery; Cerebrovascular Disease; Stroke
Sutton Richard
Clinical Cardiology, National Heart & Lung Institute, Imperial College, London, UK
Interests: Cardiac Electrophysiology and Pacing; Cardiovascular Medicine; Cardiac Rhythmology
Eliza Russu
1 Department of Vascular Surgery, Mureș County Emergency Hospital, Targu Mures, Romania and George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, Romania; 2 Regenerative Medicine Laboratory, Center for Advanced Medical and Pharmaceutical Research, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, Romania
Interests: Vascular surgery; Arteriovenous fistula; Abdominal aortic aneurysms; Carotid disease; Peripheral arterial disease; Bioengineering; Biomechanical properties; Arterial reconstruction; By-pass; Angioplasty
Paul Schoenhagen
Departments of Diagnostic Radiology and Cardiovascular Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH, United State
Interests: Aorta Center; Cardiovascular Imaging; Computed Tomography (CT Scan); Coronary Artery Calcium Score; Heart Imaging; Magnetic Resonance Imaging (MRI); Noninvasive Diagnostic Testing; Noninvasive Testing for Vascular Disease; Cardiovascular Disease
Anwen Shao
Zhejiang University, Hangzhou, China
Interests: Cerebrovascular disease, Brain tumor; Traumatic brain injury
Vijay K Sharma
Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
Interests: Acute Ischemic Stroke; Intracranial Atheroslerosis; Carotid Artery Disease; Cerebral Hemodynamics; Cerebrovascular Ultrasonography; Transcranial Doppler (TCD)
Fu-Dong Shi
China National Clinical Research Center for Neurological Diseases, Beijing Tiantan Hospital of Capital Medical University, Beijing, China
Interests: Neuroimmune Diseases; Neuroimmunology; Immune Mechanisms of Stroke; Immune Interventions in Cerebrovascular Diseases; Immune Targeting Therapy
Sadegh Shirian
Veterinary Pathology, Shahrekord University, Shahrekord, Iran
Interests: Neurodegenerative disease; Pathology and molecular pathology; Brain tumor; Regenerative medicine
Ching-Hui Sia
Department of Cardiology, National University Heart Centre Singapore, Singapore
Interests: Cardiomyopathies; Brain-Heart Interactions; Multimodality Cardiovascular Imaging; Cardiovascular Epidemiology
Lei Song
Fuwai Hospital, Chinese Academy of Medical Sciences, Beijing, China
Interests: Cardiomyopathy; Hypertrophic Cardiomyopathy
Wei Sun
Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China
Interests: Epilepsy; Neuroelectrophysiology
Zhonghua Sun
Curtin Medical School, Curtin University, Perth, Australia
Interests: Cardiovascular disease, 3D printing, virtual reality, augmented reality, mixed reality in medical application, diagnostic radiology, artificial intelligence in medical applications
Francesco Tona
Department of Cardiology, University of Padova, Padua, Veneto, Italy
Interests: Heart Transplantation; Cardiology; Doppler Echocardiography; Atherosclerosis; Echocardiography; Heart Failure; Cardiovascular Risk; Cardiovascular System; Vascular Medicine;PCI
Moris Topaz
IVT Medical Ltd., Ra'anana, Israel
Interests: Management of Localized CIED (Cardiac Implantable Electronic Devices) and Other Implantable Devices and Hard-to-heal Wounds by Targeted Ultra-high Concentrations of Antibiotics
Mehmet Turgut
Department of Neurosurgery, Adnan Menderes University, Aydın, Turkey
Interests: Tonin Adminis; Stration Satisfaction; Action Questionn; Mab Administratio
Ahmad Umar
Department of Chemistry, Najran University, Saudi Arabia
Interests: Nanoscience and Nanotechnology, Sensors, Catalysis, Energy, Electronic Devices
Giustino Varrassi
Paolo Procacci Foundation, Roma, Italy
Interests: pain medicine; pain assessment; pain management; acute pain; chronic pain; pain research; comorbidity; anesthesiology
Madeeha Subhan Waleed
Ayub Medical College,United State
Interests: Cancer; Pharmacology; Toxicology and Pharmaceutics
R. Clinton Webb
Cardiovascular Translational Research Center, Department of Cell Biology and Anatomy SmartState Endowed Chair in Biofabrication, University of South Carolina, Columbia, SC, USA
Interests: Vascular Smooth Muscle; Endothelium; Hypertension; Vasculogenic Sexual Dysfunction (Male and Female)
Claudia Wiese
Environmental and Radiological Health Sciences, Colorado State University, Colorado, United States
Interests: Biochemistry; Genetics and Molecular Biology; Medicine
George K.C. Wong
Faculty of Medicine, Chinese University of Hong Kong, Hong Kong, China
Interests: Vascular medicine; Endovascular surgery; Stroke; Aneurysm; Angiography; Cardiovascular system
Jialing Wu
Tianjin Huanhu Hospital, Tianjin, China
Interests: Stroke; Neurorehabilitation; Intelligent Medical
Dong Xu
Department of Cardiac Surgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
Interests: Coronary heart disease and prevention; Atrial fibrillation intervention and stroke; Great artery diseases intervention and stroke; Anticoagulants(NOAC) and stroke
Weihai Xu
Department of Neurology, Peking Union Medical College Hospital, Beijing, China
Interests: Intracranial atherosclerosis; Neuro-ultrasound; Brain ischemic tolerance; Orthostatic hypotension; MicroRNA regulation in stroke
Yuehui Yin
Department of Cardiology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Interests: Arrhythmia; Hypertension; Coronary heart disease; Heart failure
Jian Zhang
Fuwai Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing, China
Interests: Cardiomyopathy; Heart failure; Biomarker; Novel drugs; Clinical trials
Wei Zhang
Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University
Interests: Brain Tumor; Neurosurgery; Cancer Metabolism; Targeted Therapy; Immunotherapy
Viviane Flumignan Zétola
Federal University of Parana, Cerebrovascular Diseases Unit Coordinator, Head of Neurosonology Laboratory, Head of the Research and Technological Innovation Sector of CHC- EBSERH, Brazil
Interests: Stroke; Thrombus; Cerebrovascular Diseases; Neurology
Sertac Çiçek
West Virginia University, Morgantown, United States
Interests: Cardiac Surgery; Endocarditis; Pericardium; Valve Disease; Ischemic Cardiomyopathy
All members of the Editorial Board have identified their affiliated institutions or organizations, along with the corresponding country or geographic region. AccScience Publishing remains neutral with regard to any jurisdictional claims.
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Brain & Heart, Electronic ISSN: 2972-4139 Published by AccScience Publishing