
There are profound and underlying correlations between the brain and left atrium, from the modulation of autonomous nerve system (especially the intrinsic ANS) to the stroke originated from the embolism from left atrium and consequent cognitive impairment due to the atrial fibrillation (AF) or even patent foramen ovale (PFO). This special issue is aimed at improving the clinicians’ cognition in this field.

Atrial fibrillation and risk of cognitive impairment and dementia: Relationships, potential mechanisms, and current therapies
Cardioneuroablation for vagally mediated bradyarrhythmia: A case study with a systematic review
An overview of the anticoagulation therapy in ischemic stroke associated with non-valvular atrial fibrillation
Computer simulations in left atrial appendage occlusion: Current applications and future potential

