AccScience Publishing / JCBP / Volume 1 / Issue 1 / DOI: 10.36922/jcbp.0405
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Comorbid psychiatric disorders in a Crouzon syndrome patient: A case report

Shuangyan Li1,2† Chong Tang1,2† Yang Zhou3 Yue Gu1,2 Xian Luo1,2 Yan Xu1,2 Bin Zhang1,2*
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1 Department of Psychiatry, Sleep Medicine Center, Nanfang Hospital, Southern Medical University, Guangzhou, China
2 Guangdong-Hong Kong-Macao Greater Bay Area Center for Brain Science and Brain-Inspired Intelligence, Southern Medical University, Guangzhou, China
3 Department of Forensic Medicine, Xuzhou Medical University, Xuzhou, China
Submitted: 6 April 2023 | Accepted: 18 May 2023 | Published: 8 June 2023
© 2023 by the Author(s). This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution 4.0 International License ( )

Crouzon syndrome (CS) is a craniofacial disorder inherited in autosomal dominant manner. CS patients could present with prominent psychiatric symptoms, but few could be diagnosed with the symptoms in the psychiatry department during the first medical consultation. The patients’ emotional needs and mental health were often neglected. We reported a case of a 15-year-old girl diagnosed with psychiatric disorders during the first medical consultation in the psychiatry department since birth, presenting with characteristic features of CS, including exophthalmos, facial anomalies, and mandibular prognathism. The psychiatric symptoms were improved obviously through administering appropriate treatment. This case report emphasizes the importance of CS patients’ mental health and family’s emotional support.

Crouzon syndrome
Psychological disorder
Craniofacial dysostosis
National Natural Science Foundation of China
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Conflict of interest
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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Journal of Clinical and Basic Psychosomatics, Electronic ISSN: 2972-4414 Published by AccScience Publishing