This special issue brings together cutting-edge advances at the intersection of bioprinting and microfluidic organ-on-a-chip systems, two rapidly evolving technologies that are redefining how we model human physiology, study disease, and develop therapeutic strategies. The convergence of these two fields is accelerating the creation of in vitro models that surpass the capability of current 3D-bioprinted models.

Aims: This special issue aims to highlight innovative research, emerging methodologies, and forward-looking perspectives that advance the integration of bioprinting and microfluidic technologies. 

Scope: The scope spans fundamental science, engineering/technological innovation, and applied research, with an emphasis on systems that enhance physiological and clinical relevance. Contributions are welcomed on the following topics (but not limited to): (1) development of new bioinks, printing strategies, or microfabrication approaches; (2) engineering of perfusable, functional, or multi-tissue constructs; (3) incorporation of sensing, automation, or computational design; (4) applications in drug discovery, toxicology, regenerative medicine, or personalised therapeutics; and (5) exploration of translational, regulatory, or scalability challenges.