AccScience Publishing / IJB / Online First / DOI: 10.36922/ijb.1263
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RESEARCH ARTICLE

Design of biomedical gradient porous scaffold via a minimal surface dual-unit continuous transition connection strategy

Yuting Lv1,2 ,  Zheng Shi1 ,  Binghao Wang3,4* ,  Miao Luo3 ,  Xing Ouyang1 ,  Jia Liu3,4* ,  Hao Dong1 ,  Yanlei Sun1 ,  Liqiang Wang2,5*
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1 College of Mechanical and Electronic Engineering, Shandong University of Science and Technology, Qingdao, Shandong, China
2 State Key Laboratory of Metal Matrix Composites, Shanghai Jiao Tong University, Shanghai, China
3 Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, Guangxi, China
4 Guangxi Key Laboratory of Basic and Translational Research of Bone and Joint Degenerative Diseases, Baise, Guangxi, China
5 National Center for Translational Medicine, Shanghai Jiao Tong University, Shanghai, China
IJB 2024, 10(1), 1263 https://doi.org/10.36922/ijb.1263
Submitted: 6 July 2023 | Accepted: 11 September 2023 | Published: 8 January 2024
© 2024 by the Author(s). This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution 4.0 International License ( https://creativecommons.org/licenses/by/4.0/ )
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Abstract

In this work, a series of new gradient porous scaffolds were innovatively designed via a dual-unit continuous transition connection strategy based on the minimal surface structures (primitive [P], diamond [D], and gyroid [G]). The scaffolds were successfully prepared through selective laser melting technology. The results showed that the dual-unit continuous transition connection strategy significantly improved the mechanical properties of the connected scaffolds. The compression strength of the scaffolds was found to be (P-G)>(P-D)>(G-P)>(G-D)>(D-G)>(D-P), with the P-G structure exhibiting a compression strength of 167.7 MPa and an elastic modulus of 3.3 GPa. The mechanical properties of the porous scaffolds were primarily influenced by the outer unit type, the connection condition between different units, the unit size, and the porosity. Scaffolds with the outer P unit demonstrated better mechanical properties due to the higher mechanical strength of the P structure. The connection performance between different units varied, with P and G units forming a good continuous transition connection, while the connection performance between P and D units was the weakest. The dual-unit continuous transition connection strategy offers a promising approach to optimize the connection performance of different units, providing new insights into the design of medical porous scaffolds.

Keywords
Biomedical porous scaffold
Selective laser melting
Minimal surface
Mechanical property
Funding
Not applicable.
Conflict of interest
The authors declare no conflicts of interest.
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International Journal of Bioprinting, Electronic ISSN: 2424-8002 Print ISSN: 2424-7723, Published by AccScience Publishing
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