AccScience Publishing / IJB / Volume 9 / Issue 4 / DOI: 10.18063/ijb.735
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RESEARCH ARTICLE

Design and biomechanical analysis of patient-specific porous tantalum prostheses for knee joint revision surgery

Shilong Mao1† Yang Liu1† Fuyou Wang2 Peng He3 Xianzhe Wu3* Xingshuang Ma1* Yanfeng Luo1*
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1 College of Bioengineering, Chongqing University; Key Laboratory of Biorheological Science and Technology (Chongqing University), Ministry of Education, Chongqing, 400030, China
2 Southwest Hospital of Army Medical University, Chongqing, 400038, China
3 Chongqing Institute of Optics and Mechanics, Chongqing, 401122, China
(This article belongs to the Special Issue Additive Manufacturing of Functional Biomaterials)
© Invalid date by the Author(s). This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution 4.0 International License ( https://creativecommons.org/licenses/by/4.0/ )
Abstract

Artificial joint revision surgery, as an increasingly common surgery in orthopedics, often requires patient-specific prostheses to repair the bone defect. Porous tantalum is a good candidate due to its excellent abrasion and corrosion resistance and good osteointegration. Combination of 3D printing technology and numerical simulation is a promising strategy to design and prepare patient-specific porous prostheses. However, clinical design cases have rarely been reported, especially from the viewpoint of biomechanical matching with the patient’s weight and motion and specific bone tissue. This work reports a clinical case on the design and mechanical analysis of 3D-printed porous tantalum prostheses for the knee revision of an 84-year-old male patient. Particularly, standard cylinders of 3D-printed porous tantalum with different pore size and wire diameters were first fabricated and their compressive mechanical properties were measured for following numerical simulation. Subsequently, patientspecific finite element models for the knee prosthesis and the tibia were constructed from the patient’s computed tomography data. The maximum von Mises stress and displacement of the prostheses and tibia and the maximum compressive strain of the tibia were numerically simulated under two loading conditions by using finite element analysis software ABAQUS. Finally, by comparing the simulated data to the biomechanical requirements for the prosthesis and the tibia, a patient-specific porous tantalum knee joint prosthesis with a pore diameter of 600 μm and a wire diameter of 900 μm was determined. The Young’s modulus (5719.32 ± 100.61 MPa) and yield strength (172.71 ± 1.67 MPa) of the prosthesis can produce both sufficient mechanical support and biomechanical stimulation to the tibia. This work provides a useful guidance for designing and evaluating a patient-specific porous tantalum prosthesis.

Keywords
Porous tantalum
Finite element analysis
Artificial joint revision surgery
Biomechanics
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International Journal of Bioprinting, Electronic ISSN: 2424-8002 Print ISSN: 2424-7723, Published by AccScience Publishing