Artificial intelligence in epilepsy education
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The emergence of artificial intelligence (AI) has revolutionized the landscape of epilepsy education and management by providing innovative solutions to the challenges of diagnosis, treatment, and patient care. This review evaluates the multifaceted role of AI in epilepsy, focusing on its impact on early diagnosis, seizure prediction, and the development of personalized treatment plans. AI tools, including machine learning algorithms and neural networks, have demonstrated significant promise in enhancing diagnostic accuracy and identifying epileptic patterns. This study explores various AI-driven educational platforms designed to improve the knowledge and skills of healthcare professionals, patients, and caregivers in managing epilepsy. Moreover, AI applications in wearable devices and mobile health platforms facilitate real-time monitoring and patient engagement, ultimately improving quality of life. However, integrating AI into clinical practice presents several challenges, including the need for large and high-quality datasets, interdisciplinary collaboration, data privacy, and ethical considerations. This review highlights these barriers while suggesting uniform protocols and frameworks for efficiently translating AI technologies into clinical practice. It underscores AI’s transformative potential in epilepsy care and education, advocating for ongoing research and collaborative efforts among technologists, clinicians, and educators, while emphasizing the importance of user-friendly design, regular assessments, and ethical considerations to maximize AI’s impact in this critical field.
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- Murray S, Labbé S, Kothare S, et al. Identifying the educational needs of physicians in pediatric epilepsy in order to improve care: Results from a needs assessment in Germany, Spain, and the United States. Epileptic Disord. 2018;20(4):239-256. doi: 10.1684/epd.2018.0989
- Hughes S, Finnegan T, Benbadis S. Improving diagnostic accuracy in epilepsy: Effect of online medical education on EEG education among neurologists. Neurology. 2018;90(15):P3.260. doi: 10.1212/WNL.90.15_supplement.P3.260
- Weber DJ, Moeller JJ. Epilepsy education: Recent advances and future directions. Curr Neurol Neurosci Rep. 2019;19(6):35. doi: 10.1007/s11910-019-0946-7
- Winesett SP, Amankwah EK, Nguyen ATH, Sibinga E. Online educational curriculum in pediatric epilepsy: A pilot study. J Am Assoc Nurse Pract. 2020;33(11):999-1006. doi: 10.1097/JXX.0000000000000492
- Udegbe NFC, Ebulue NOR, Ebulue NCC, Ekesiobi NCS. The role of artificial intelligence in healthcare: A systematic review of applications and challenges. Int Med Sci Res J. 2024;4(4):500-508. doi: 10.51594/imsrj.v4i4.1052
- Maleki Varnosfaderani S, Forouzanfar M. The role of AI in hospitals and clinics: Transforming healthcare in the 21st century. Bioengineering (Basel). 2024;11(4):337. doi: 10.3390/bioengineering11040337
- Subhan M, Faisal S, Khan MU, et al. Review on AI-driven innovations in stroke care: Enhancing diagnostic accuracy, treatment efficacy, and rehabilitation outcomes. J Adv Med Med Res. 2024;36(9):309-326. doi: 10.9734/jammr/2024/v36i95578
- Skvortsov VV, Fastova AA, Panchenko VI. Epilepsy in the practice of a family doctor. J Fam Med. 2023;(11):33-40. doi: 10.33920/med-10-2311-04
- Adamu A, Chen R, Li A, Xue G. Epilepsy in Asian countries. Acta Epileptol. 2023;(5):25. doi: 10.1186/s42494-023-00136-1
- Kawaguchi N, Terada K. Diagnosis and classification of epilepsy: Clinical reasoning. Brain Nerve. 2023;75(4):291-296. doi: 10.11477/mf.1416202327
- Uysal S. Functional Neuroanatomy and Clinical Neuroscience: Foundations for Understanding Disorders of Cognition and Behavior: Epilepsy. New York: Oxford Academic; 2023. doi: 10.1093/oso/9780190943608.001.0001
- Hubbard J, Binder D. Astrocytes and Epilepsy: Types of Epilepsy. Amsterdam, Netherlands: Elsevier Science & Technology Books; 2016. doi: 10.1016/B978-0-12-802401-0.00004-1
- Danesi M. Classification of the epilepsies: An investigation of 945 patients in a developing country. Epilepsia. 1985;26(2):131-136. doi: 10.1111/j.1528-1157.1985.tb05396.x
- Ghosh R, Arunjyoti B. Educational needs of persons with epilepsy: A qualitative study. Indian J Contin Nurs Educ. 2023;24(1):74-79. doi: 10.4103/ijcn.ijcn_118_21
- Tschudnig M, Sommer M, Simon UK. Stakeholder views of epilepsy in the biology classroom: A qualitative exploratory pilot study. Educ Sci. 2023;13(2):172. doi: 10.3390/educsci13020172
- Pellinen J. Treatment gaps in epilepsy. Front Epidemiol. 2022;2:976039. doi: 10.3389/fepid.2022.976039
- Kaczmarek I, Jabłoński S, Steinborn B. Children with epilepsy: Specific learning difficulties. Acta Neuropsychol. 2016;14(3):281-294. doi: 10.5604/17307503.1222842
- Watkins LV, Linehan C, Brandt C, Snoeijen-Schouwenaars F, McGowan P, Shankar R. Epilepsy in adults with neurodevelopmental disability - what every neurologist should know. Epileptic Disord. 2022;24(1):9-25. doi: 10.1684/epd.2021.1366
- Finnegan TF, Lubarda J, Chung S. Online CME-certified expert panel discussion improves awareness among neurologists regarding seizure freedom in patients with epilepsy (P14-2.003). Neurology. 2023;100:2468. doi: 10.1212/wnl.0000000000202578
- Casciato S, Morano A, Ricci L, et al. Knowledge and attitudes of neurologists toward epilepsy surgery: An Italian survey. Neurol Sci. 2022;43(7):4453-4461. doi: 10.1007/s10072-022-06025-8
- The Lancet Neurology. Time to end the stigma of epilepsy. Lancet Neurol. 2023;22(4):283. doi: 10.1016/s1474-4422(23)00084-4
- Thom M, Boldrini M, Bundock E, Sheppard MN, Devinsky O. Review: The past, present and future challenges in epilepsy‐related and sudden deaths and biobanking. Neuropathol Appl Neurobiol. 2017;44(1):32-55. doi: 10.1111/nan.12453
- Onesi-Ozigagun O, Ololade Y, Eyo-Udo N, Ogundipe D. Revolutionizing education through AI: A comprehensive review of enhancing learning experiences. Int J Appl Res Soc Sci. 2024;6(4):589-607. doi: 10.51594/ijarss.v6i4.1011
- Nasir M, Hasan M, Adlim A, Syukri M. Utilizing artificial intelligence in education to enhance teaching effectiveness. Proc Int Conf Educ. 2024;2(1):280-285.
- Baidya M, Kumar CA. Artificial intelligence in education: Understanding benefits, limitations, and prospects for the future. Int J Multidiscip Res. 2024;6(2):1-9. doi: 10.36948/ijfmr.2024.v06i02.16699
- Xu Z. AI in education: Enhancing learning experiences and student outcomes. Appl Comput Eng. 2024;51(1):104-111. doi: 10.54254/2755 2721/51/20241187
- Castro GPB, Chiappe A, Rodriguez DFB, Sepulveda FG. Harnessing AI for education 4.0: Drivers of personalized learning. Electron J E-Learn. 2024;22(5):1-14. doi: 10.34190/ejel.22.5.3467
- Dunusinghe AV, Ranasinghe TKS, Gamage JGA, Perera KGD, Samantha Thelijjagoda S, Gunatilake P. AI-Powered Smart and Personalized Education Platform. In: 2022 International Conference on Innovative Computing, Intelligent Communication and Smart Electrical Systems (ICSES). 2023. p. 1-7. doi: 10.1109/icses60034.2023.10465439
- Lei L. Research on Personalized Education Recommendation Algorithm based on Artificial Intelligence. In: 2023 International Conference on Applied Physics and Computing (ICAPC). 2023. p. 531-535. doi: 10.1109/icapc61546.2023.00104
- Rusinovich Y, Rusinovich V. Prevention of Artificial Intelligence (AI) misuse in online medical education. Web3 J ML Health Sci. 2024;1(1). doi: 10.62487/8ny3zh09
- Nagi F, Salih R, Alzubaidi M, et al. Applications of Artificial Intelligence (AI) in medical education: A scoping review. Stud Health Technol Inform. 2023;305:648-651. doi: 10.3233/shti230581
- Ernawati I, Yasin N, Setyopranoto I, Ikawati Z. Effect of mobile health applications on improving self-management knowledge and seizure control in epilepsy patients: A scoping review. Healthc Inform Res. 2024;30(2):127-139. doi: 10.4258/hir.2024.30.2.127
- Hamzah HI, Tuan Muda TZ, Saad MN. Interactive game “purple seahorse” raises public awareness, caring for individuals with epilepsy. Int J Bus Technol Manag. 2024;6(1):692-706. doi: 10.55057/ijbtm.2024.6.1.57
- Buscioni L, Di Gennaro G, Passamonti C. Personalized support programs with innovative digital tools to manage and monitor patients suffering from epilepsy: EpiOnApp case study. Glob Reg Health Technol Assess. 2023;10(Suppl 1):4. doi: 10.33393/grhta.2023.2888
- Burbach F, Lecce F, Allen VM, Porter CM. A conversational, virtual, avatar-led cognitive behavioral therapy app intervention for improving the quality of life and mental health of people with epilepsy: Protocol for a randomized controlled trial. JMIR Res Protoc. 2022;11(11):e40361. doi: 10.2196/40261
- Arkhipov VV, Burmistrova NI. Automated Information systems as a new approach to risk management of pharmacotherapy in the treatment of epilepsy. Saf Risk Pharmacother. 2022;10(2):151-160. doi: 10.30895/2312-7821-2022-10-2-247
- Komasawa N, Yokohira M. Simulation-based education in the artificial intelligence era. Cureus. 2023;15(6):e40940. doi: 10.7759/cureus.40940
- Farrukh K. Simulation based inter-professional education - integrating theory, practice and healthcare professionals. J Bahria Univ Med Dent Coll. 2022;13(01):73-74. doi: 10.51985/jbumdc2022158
- Rayburn D, Faris G, Ahmed R, et al. Utilizing simulation to improve pre-hospital medical care for pediatric seizure. Int J Healthc Simul. 2023:1-13. doi: 10.54531/zola9724
- Jaykar A. How artificial intelligence is used to detect epileptic EEG patterns with perfection? Int Res J Mod Eng Technol Sci. 2023;5(10):992-1000. doi: 10.56726/IRJMETS45230
- Mucci A, Green W, Hill L. Incorporation of artificial intelligence in healthcare professions and patient education for fostering effective patient care. New Dir Adult Contin Educ. 2024;2024(181):51-62. doi: 10.1002/ace.20521
- Stibbs P, Woo J, Brody T. Utilization of AI-based tools like ChatGPT in the Training of medical students and interventional radiology residents: Opportunities, challenges, and implications. SciOpen Posters. 2023. doi: 10.14293/p2199-8442.1.sop-.pftabj.v1
- Shankar PR. Artificial intelligence in health professions education. Arch Med Health Sci. 2022;10(2):256-261. doi: 10.4103/amhs.amhs_234_22
- Chung Y, Jeon Y, Yoo S, Kim H, Hwang H. Big data analysis and artificial intelligence in epilepsy - common data model analysis and machine learning-based seizure detection and forecasting. Clin Exp Pediatr. 2022;65(6):272-282. doi: 10.3345/cep.2021.00766
- Hannun A, Rajpurkar P, Haghpanahi M, et al. Cardiologist-level arrhythmia detection and classification in ambulatory electrocardiograms using a deep neural network. Nat Med. 2019;25(1):65-69. doi: 10.1038/s41591-018-0268-3
- Zhou F, Wang J. Heartbeat classification method combining multi-branch convolutional neural networks and transformer. iScience. 2024;27(3):109307. doi: 10.1016/j.isci.2024.109307
- Siddiqui M, Morales-Menendez R, Huang X, Hussain N. A review of epileptic seizure detection using machine learning classifiers. Brain Inform. 2020;7(1):5. doi: 10.1186/s40708-020-00105-1
- Yang Y, Truong N, Maher C, Nikpour A, Kavehei O. Continental generalization of a human-in-the-loop AI system for clinical seizure recognition. Expert Syst Appl. 2022;207:118083. doi: 10.1016/j.eswa.2022.118083
- Mirowski P, LeCun Y, Madhavan D, Kuzniecky R. Comparing SVM and Convolutional Networks for Epileptic Seizure Prediction from Intracranial EEG. In: 2008 IEEE Workshop on Machine Learning for Signal Processing. Cancun, Mexico; 2008. p. 244-249. doi: 10.1109/MLSP.2008.4685487
- Pedersen M, Pardoe H, Weger A, et al. Towards responsible artificial intelligence in medicine: Reflections from the Australian Epilepsy Project. OSFPreprints [Preprint]. 2023.
- Balta N. Ethical considerations in using AI in educational research. J Res Didactical Sci. 2023;2(1):14205. doi: 10.51853/jorids/14205
- Huang L. Ethics of artificial intelligence in education: Student privacy and data protection. Sci Insights Educ Front. 2023;16(2):2577-2587. doi: 10.15354/sief.23.re202
- Pascual D, Amirshahi A, Aminifar A, Atienza D, Ryvlin P, Wattenhofer R. EpilepsyGAN: Synthetic epileptic brain activities with privacy preservation. IEEE Trans Biomed Eng. 2020;68(8):2435-2446. doi: 10.1109/TBME.2020.3042574
- Athar A, Shoka E, Dessouky M, El-Sayed A, Hemdan E. An efficient CNN based epileptic seizures detection framework using encrypted EEG signals for secure telemedicine applications. Alex Eng J. 2022;65:399-412. doi: 10.1016/j.aej.2022.10.014
- Saeizadeh A, Schonholtz D, Uvaydov D, Guida R, Demirors E, Johari P, Jimenez J. SeizNet: An AI-enabled implantable sensor network system for seizure prediction. arXiv. 2024. doi: 10.48550/arxiv.2401.06644
- Zhao W, Wang WF, Patnaik LM, et al. Residual and bidirectional LSTM for epileptic seizure detection. Front Comput Neurosci. 2024;18:1415967. doi: 10.3389/fncom.2024.1415967
- Mbiazi D, Bhange M, Babaei M, Sheth I, Kenfack P.Survey on AI ethics: A socio-technical perspective. arXiv. 2023. doi: 10.48550/arxiv.2311.17228
- Shuford J. Examining ethical aspects of AI: Addressing bias and equity in the discipline. J Artif Intell Gen Sci. 2024;3(1):262-280. doi: 10.60087/jaigs.v3i1.119
- Livieri G, Anastasopoulou C, Briola K, Nikolopoulou P, Efthymiou I. Ethical issues arising from the use of AI in drug discovery. J Polit Ethics New Technol AI. 2024;3(1):e37093. doi: 10.12681/jpentai.37093
- Jeon Y, Chung YG, Joo T, Kim H, Hwang H, Kim K. Deep learning-based detection of epileptiform discharges for self-limited epilepsy with centrotemporal spikes. IEEE Trans Neural Syst Rehabil Eng. 2022;30:2939-2949. doi: 10.1109/TNSRE.2022.3215526
- Altaheri H, Muhammad G, Alsulaiman M, Amin S, Altuwaijri G, Abdul W. Deep learning techniques for classification of electroencephalogram (EEG) motor imagery (MI) signals: A review. Neural Comput Appl. 2023;35:14681-14722. doi: 10.1007/s00521-021-06352-5
- Lasefr Z, Elleithy K, Reddy RR, Abdelfattah E, Faezipour M. An epileptic seizure detection technique using EEG signals with mobile application development. Appl Sci. 2023;13(17):9571. doi: 10.3390/app13179571
- Detti P, Vatti G, Zabalo Manrique de Lara G. EEG synchronization analysis for seizure prediction: A study on data of noninvasive recordings. Processes. 2020;8(7):846. doi: 10.3390/pr8070846
- Timan T, Mann Z. Data protection in the era of artificial intelligence: Trends, existing solutions and recommendations for privacy-preserving technologies. In: The Elements of Big Data Value. Cham: Springer; 2021. p. 153-175. doi: 10.1007/978-3-030-68176-0_7
- Theodore W, Spencer S, Wiebe S, et al. Epilepsy in North America: A report prepared under the auspices of the global campaign against epilepsy, the International Bureau for Epilepsy, the International League Against Epilepsy, and the World Health Organization. Epilepsia. 2006;47(10):1700-1722. doi: 10.1111/j.1528-1167.2006.00633.x
- Wang M, Zhang Y, Li H, et al. Explainable AI for epilepsy diagnosis: A review. IEEE Access. 2021;9:102-117. doi: 10.1109/ACCESS.2021.3056789
- Shoeibi A, Khodatars M, Ghassemi N, et al. Epileptic seizures detection using deep learning techniques: A review. Int J Environ Res Public Health. 2021;18(11):5780. doi: 10.3390/ijerph18115780
- World Health Organization. World Health Statistics 2023: Monitoring Health for the SDGs, Sustainable Development Goals. Geneva: World Health Organization; 2023. Available from: https://www.who.int/publications/i/ item/9789240094703 [Last accessed on 2024 Nov 01].
- Ahmed M, Sinha N, Ghaderpour E, Phadikar S, Ghosh R. A novel baseline removal paradigm for subject-independent features in emotion classification using EEG. Bioengineering (Basel). 2023;10(1):54. doi: 10.3390/bioengineering10010054
- Patel U, Anwar A, Saleem S, et al. Artificial intelligence as an emerging technology in the current care of neurological disorders. J Neurol. 2021;268(5):1623-1642. doi: 10.1007/s00415-019-09518-3
- Kerr WT, McFarlane KN. Machine learning and artificial intelligence applications to epilepsy: A review for the practicing epileptologist. Curr Neurol Neurosci Rep. 2023;23:869-879. doi: 10.1007/s11910-023-01318-7