The convergence of bioprinting, biomaterials, and organoid research represents a groundbreaking frontier in regenerative medicine and tissue engineering. This special issue presents a collection of articles that highlight the innovative approaches being developed to manufacture complex structures with high biological similarity. Bioprinting technologies not only enhance the feasibility of tissue regeneration but also facilitate the manipulation of organoids that mimic organ functions, offering valuable platforms for drug discovery and disease modeling. Throughout this issue, the latest research and applications in bioprinting are expected to be explored, addressing both the challenges and opportunities that lie ahead. By fostering interdisciplinary collaboration, we aim to provide insights into how these technologies can revolutionize patient care and improve therapeutic outcomes, paving the way for a new era of personalized medicine.