AccScience Publishing / ARNM / Online First / DOI: 10.36922/arnm.4813
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SHORT COMMUNICATION

Positron emission tomography/computed tomography in B-cell non-Hodgkin’s lymphoma at Hanoi Oncology Hospital

Phuong Pham Cam1,2,3 ,  Thai Pham Van1,3* ,  Thang Nguyen Van4 ,  Nien Vu Thi2
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1 The Nuclear Medicine and Oncology Center, Bach Mai Hospital, Hanoi, Vietnam
2 Department of Oncology and Nuclear Medicine, University of Medicine and Pharmacy National University, Hanoi, Vietnam
3 Department of Nuclear Medicine, Hanoi Medical University, Hanoi, Vietnam
4 Department of Nuclear Medicine, Hanoi Oncology Hospital, Hanoi, Vietnam
ARNM, 4813 https://doi.org/10.36922/arnm.4813
Submitted: 10 September 2024 | Accepted: 8 November 2024 | Published: 9 December 2024
© 2024 by the Author(s). This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution 4.0 International License ( https://creativecommons.org/licenses/by/4.0/ )
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Abstract

This study aimed to review 18fluoro-2-deoxy-d-glucose positron emission tomography/computed tomography (18FDG PET/CT) imaging characteristics of B-cell non-Hodgkin’s lymphoma (NHL) at Hanoi Oncology Hospital. PET/CT helps accurately assess the NHL stage compared with other diagnostic imaging methods, such as CT and magnetic resonance imaging. In this retrospective descriptive study, 86 newly diagnosed B-cell NHL cases were histopathologically and immunohistochemically examined at Hanoi Oncology Hospital between January 2018 and December 2022. Patients underwent 18FDG PET/CT for pretreatment staging. The stages before and after PET/CT were evaluated and compared. Before PET/CT, 26 (30.2%), 29 (33.7%), 15 (17.5%), and 16 (18.6%) patients were in stages I, II, III, and IV, respectively. After PET/CT, the rates of Stage I, II, III, and IV cases were 22.1%, 26.8%, 20.9%, and 30.2%, respectively. PET/CT results increased the stage in 21/86 patients (24.4%). The proportion of patients with advanced stages after PET/CT in the rapidly progressing histopathology group was higher (25%) than the slowly progressing histopathology group (21.4%), and the difference was not significant. Therefore, PET/CT is critical for accurately determining the disease stage of B-cell NHL, thereby helping to detect additional lesions missed by conventional imaging diagnostic tools.

Keywords
B-cell non-Hodgkin’s lymphoma
18FDG PET/CT
Pre-PET/CT stage
Post-PET/CT stage
Funding
None.
Conflict of interest
Phuong Pham Cam is an Editorial Board Member of this journal but was not in any way involved in the editorial and peer-review process conducted for this paper, directly or indirectly. Separately, other authors declared that they have no known competing financial interests or personal relationships that could have influenced the work reported in this paper.
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Advances in Radiotherapy & Nuclear Medicine, Electronic ISSN: 2972-4392 Published by AccScience Publishing
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