AccScience Publishing / ITPS / Volume 7 / Issue 1 / DOI: 10.36922/itps.1202
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Antiplatelet, anticoagulation, and elective aneurysm treatments in neurological patients

Anjali Patel1 Daisy Valle1 Drashti Patel1 Marco Foreman1 Akash Nijhawan2 Devon Foster2 Alexander Nguyen3 Brandon Lucke-Wold4*
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1 University of Florida College of Medicine, Gainesville, FL, USA
2 Florida International University Herbert Wertheim College of Medicine, Miami, FL, USA
3 Creighton University School of Medicine, Omaha, Nebraska, USA
4 Department of Neurosurgery, University of Florida, Gainesville, FL, USA
INNOSC Theranostics and Pharmacological Sciences 2024, 7(1), 1202 https://doi.org/10.36922/itps.1202
Submitted: 29 June 2023 | Accepted: 23 August 2023 | Published: 18 October 2023
© 2023 by the Author(s). This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution -Noncommercial 4.0 International License (CC BY-NC 4.0) ( https://creativecommons.org/licenses/by-nc/4.0/ )
Abstract

Developing more specialized care for neurological disorders, such as aneurysms, arteriovenous malformations, and strokes, can revolutionize patient healthcare and outcomes. With the advent of surgical techniques such as flow diversion, non-stent- and stent-assisted coiling, and catheter embolization for elective aneurysm treatment in neurological patients, the adverse effects and morbidities associated with aneurysms can be reduced. This paper aims to highlight three specific strengths and weaknesses of the newly emerged techniques. Flow diversion devices involve placing a stent in the parent artery, whereas Woven EndoBridge embolization involves manipulation of the wall of the artery without the administration of dual-antiplatelet therapy. In addition to aneurysm treatment, the administration of antiplatelets and anticoagulants is helpful in disrupting the coagulation cascade. As stated in the new and enhanced guidelines released by the American Heart Association, the administration of dual anticoagulants is beneficial to the patients if they have low ischemic severity. Understanding the various benefits and complications associated with each treatment can allow clinicians to gain insight into the potential trajectory of treatment for different patients.

Keywords
Aneurysm
Stent-assisted embolization
Antiplatelet therapy
Woven Endobridge embolization
Catheter embolization
Funding
None.
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Conflict of interest
The authors declare no conflicts of interest.
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INNOSC Theranostics and Pharmacological Sciences, Electronic ISSN: 2705-0823 Published by AccScience Publishing