AccScience Publishing / BH / Volume 1 / Issue 2 / DOI: 10.36922/bh.1005
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Operative treatment for umbilical venous catheter-related Staphylococcus aureus infective endocarditis with subsequent septic thrombosis: A case report

Cassandra DeVol1 Christopher M. McDaniel2 Nupur Singh3 Pilar Anton Martin4*
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1 Division of Pediatric Cardiology, University of Tennessee Health Science Center/Le Bonheur Children’s Hospital, Memphis, TN, USA
2 Division of Internal Medicine, Baptist Memorial Hospital-DeSoto, Memphis, TN, USA
3 Department of Medical Education, College of Medicine, University of Tennessee Health Science Center, Memphis, TN, USA
4 Division of Anesthesia and Critical Care Medicine, Children’s Hospital of Philadelphia, Philadelphia, PA, USA
Brain & Heart 2023, 1(2), 1005
Submitted: 26 May 2023 | Accepted: 25 July 2023 | Published: 23 August 2023
© 2023 by the Author(s). This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution 4.0 International License ( )

especially with the increasing use of indwelling catheters. In some cases, surgical excision becomes imperative to ensure adequate source control and mitigate the burden of infection. Herein, we present a compelling case involving a term neonate who developed refractory Staphylococcus aureus infective endocarditis, followed by septic emboli due to a thrombus associated with a malpositioned indwelling umbilical venous catheter (UVC). Thrombosis and infective endocarditis resolved after surgical resection, a 6-week course of antibiotics, and anticoagulation therapy for 3 months. This case report highlights the risk of thrombosis arising from malpositioned UVCs, the potential complications, and the treatment options.

Umbilical venous catheter
Infective endocarditis
Septic embolism
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Conflict of interest
The authors declare no conflicts of interest.
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Brain & Heart, Electronic ISSN: 2972-4139 Published by AccScience Publishing