AccScience Publishing / TD / Online First / DOI: 10.36922/TD025120022
CASE REPORT

Challenges and considerations in diagnosing mature teratoma during pregnancy: A case report

Sumaira Siddiqui1*
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1 Department of Pathology, Clinilabs and Research, Lucknow, Uttar Pradesh, India
Tumor Discovery, 025120022 https://doi.org/10.36922/TD025120022
Received: 20 March 2025 | Revised: 1 June 2025 | Accepted: 3 June 2025 | Published online: 30 June 2025
© 2025 by the Author(s). This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution 4.0 International License ( https://creativecommons.org/licenses/by/4.0/ )
Abstract

The progression of rapidly growing teratomas in pregnancy may be influenced by hormonal and genetic factors. The current report is about a unique case involving a mature teratoma with rapid growth characteristics, yet it did not lead to any complications throughout pregnancy of a primigravida. The benign mature teratoma was identified via antenatal ultrasound during the first trimester. In this case, the patient experienced no adverse effects, and the size of the ovarian teratoma showed a gradual increasing trend during pregnancy without resulting in any complications. In summary, mature teratoma is a benign tumor with a good prognosis, and if fetal distress is detected, cesarean section should be recommended.

Keywords
Mature teratoma
Pregnancy
Fetal distress
Cesarean section
Funding
None.
Conflict of interest
The author declares no conflicts of interest.
References
  1. Peterson WF. Malignant degeneration of benign cystic teratomas of the overy; A collective review of the literature. Obstet Gynecol Surv. 1957;12(6):793-830. doi: 10.1097/00006254-195712000-00001

 

  1. Pantoja E, Noy MA, Axtmayer RW, Colon FE, Pelegrina I. Ovarian dermoids and their complications. Comprehensive historical review. Obstet Gynecol Surv. 1975;30(1):1-20. doi: 10.1097/00006254-197501000-00001

 

  1. Westhoff C, Pike M, Vessey M. Benign ovarian teratomas: A population-based case-control study. Br J Cancer. 1988;58(1):93-98. doi: 10.1038/bjc.1988.171

 

  1. Joudar I, El Abbassi I, Khalloufi C, Jalal M, Lamrissi A, Bouhya S. Mature teratoma during pregnancy: A case report. J Case Rep Images Obstet Gynecol. 2023;9(1):70-74. doi: 10.5348/100150Z08IJ2023CR

 

  1. Ueda Y, Sekiyama K, Ito M, Egawa H, Tokushige M, Takakura K. Displacement of ovarian mature cystic teratoma following rupture during pregnancy: Case report. Japanese J Gynecol Obstet Endosc. 2013;29(1):84-87.

 

  1. Sheng Y, Yuan J, Wang J, Wang L, Li Y, Wang Y. Ovarian mature cystic teratoma is an independent risk factor for the premature rupture of membranes in pregnancy: A single-center retrospective study. Int J Womens Health. 2022;14:1477-1487. doi: 10.2147/IJWH.S381297

 

  1. Osto M, Brooks A, Khan A. Ovarian cystic teratoma in pregnant women: Conservative management or prophylactic oophorectomy? Cureus. 2021;13(8):e17354. doi: 10.7759/cureus.17354

 

  1. Ahmed A, Lotfollahzadeh S. Cystic teratoma. In: StatPearls. Treasure Island, FL: StatPearls Publishing; 2025. Available from: https://www.ncbi.nlm.nih.gov/books/NBK564325 [Last accessed on 2023 Jun 03].

 

  1. Bouzoubaa W, Jayi S, Alaoui FZF, Chaara H, Melhouf MA. Immature teratoma of the ovary: About a case. Pan Afr Med J. 2017;27:263. doi: 10.11604/pamj.2017.27.263.6400

 

  1. Chenana A, Kouach J, Moussaoui D, Dehayni M. Tératome immature de l’ovaire et grossesse: A propos d’un cas/ [Immature teratoma of the ovary and pregnancy: A case report]. Int J Innov Appl Stud. 2016;15(3):503-514.

 

  1. Tan KH, Chen KC, Wang TL, Chong CF, Chen CC. Ovarian cystic teratoma torsion in pregnancy. Emerg Med J. 2010;27:879-880. doi: 10.1136/emj.2008.063883

 

  1. Tariel O, Huissoud C, Rudigoz RC, Dubernard G. Presumed benign ovarian tumors during pregnancy. J Gynecol Obstet Biol Reprod (Paris). 2013;42(8):842-855. doi: 10.1016/j.jgyn.2013.09.038

 

  1. Walid MS, Boddy MG. Bilateral dermoid cysts of the ovary in a pregnant woman: Case report and review of the literature. Arch Gynecol Obstet. 2009;279:105-108. doi: 10.1007/s00404-008-0695-3

 

  1. Haddada S, Selleret L, Fedida B, et al. Adnexal masses and pregnancy: Which diagnosis and which imaging? Imagerie Femme. 2017;27(2):104-110.

 

  1. Srisajjakul S, Prapaisilp P, Bangchokdee S. Imaging features of unusual lesions and complications associated with ovarian mature cystic teratoma. Clin Imaging. 2019;57:115-123. doi: 10.1016/j.clinimag.2019.05.013

 

  1. Sahin H, Abdullazade S, Sanci M. Mature cystic teratoma of the ovary: A cutting edge overview on imaging features. Insights Imaging. 2017;8(2):227-241. doi: 10.1007/s13244-016-0539-9

 

  1. Nguyen HT, Trinh NB, Tran NH, Nguyen PN. Massive mature cystic teratoma presenting as ovarian cancer grade IIIC in a young Vietnamese woman: A case report. Oman Med J. 2025;40:1-8. doi: 10.5001/omj.2028.17

 

  1. Cong L, Wang S, Yeung SY, Lee JH, Chung JP, Chan DY. Mature cystic teratoma: An integrated review. Int J Mol Sci. 2023;24(7):6141. doi: 10.3390/ijms24076141

 

  1. Aggarwal P, Kehoe S. Ovarian tumours in pregnancy: A literature review. Eur J Obstet Gynecol Reprod Biol. 2011;155(2):119-124. doi: 10.1016/j.ejogrb.2010.11.023

 

  1. Cohen-Herriou K, Semal-Michel S, Lucot JP, Poncelet E, Rubod C. Management of ovarian cysts during pregnancy: Lille’s experience and literature review. Gynecol Obstet Fertil. 2013;41(1):67-72. doi: 10.1016/j.gyobfe.2012.12.001

 

  1. Chen LH, Chang SD, Huang HY, Wang HS, Soong YK, Wu HM. Repeated pregnancy with concomitant presence of ovarian teratoma: A case report and literature review. Taiwan J Obstet Gynecol. 2017;56(5):694-696. doi: 10.1016/j.tjog.2017.08.021

 

  1. Schreck AM, Mikdachi HF. Benign ovarian tumors in pregnancy: A case report of metachronous ipsilateral recurrent mucinous cystadenoma in initial pregnancy and mature cystic teratoma in subsequent pregnancy. Cureus. 2019;11(1):e3818. doi: 10.7759/cureus.3818

 

  1. Gbary-Lagaud E, Effoh D, Ehui A, Koffi S, Houphouet- Mwandji C, Adjoby R. Mature ovarian teratoma and pregnancy about a case in Abidjan Cote d’Ivoire. J Gynecol Obstet. 2020;8(4):117-121. doi: 10.11648/j.jgo.20200804.19

 

  1. Spasimir TS. А collision tumor of the ovary during pregnancy-rare combination. J Med Clin Res Rev. 2019;3(6):1-3.

 

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Tumor Discovery, Electronic ISSN: 2810-9775 Print ISSN: 3060-8597, Published by AccScience Publishing