The field of tumor immunology has evolved into a pivotal discipline bridging cancer biology and immunology, focusing on deciphering the dynamic interplay between tumors and host immune defenses. Current research highlights the dual role of immune cells in both suppressing and promoting tumor progression, with emerging insights into mechanisms of immune evasion—such as regulatory T-cell infiltration, myeloid-derived suppressor cell (MDSC) activity, and metabolic reprogramming of tumor-associated macrophages (TAMs). Advances in multi-omics, spatial transcriptomics, and AI-driven analytics are revolutionizing our understanding of tumor antigens, immune checkpoints, and microenvironmental crosstalk.
Application of natural killer cell-based immunotherapy in lung cancer treatment
Targeted inhibition of chondroitin polymerizing factor suppresses CD5+ diffuse large B-cell lymphoma progression through the PI3K/AKT signaling and RhoA/ROCK axis
Circulating cell-free DNA in clinical management of hepatocellular carcinoma: Updates on detection, diagnosis, treatment, and recurrence
Endogenous and dietary geranylgeranoic acid: A mini review on its role in hepatic tumor suppression
Sulforaphane selectively inhibits glucose metabolism in PIK3CA-mutated ovarian cancer cells
An update on the role of immune checkpoint inhibitors in lung cancer: A narrative systematic review
Effect of γδT-cell infiltration on the prognosis of hepatocellular carcinoma