AccScience Publishing / EJMO / Online First / DOI: 10.36922/EJMO026260310
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COMMENTARY

Artificial intelligence in periodontal disease management: Opportunities and challenges

Giuseppe Piedigace1† Silvia Drago1† Alessandro Polizzi1,2 Giorgia Marmo1 Marco Mascitti3 Saturnino Marco Lupi4 Gaetano Isola1,2*
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1 Department of General Surgery and Surgical-Medical Specialties, School of Dentistry, Univer-sity of Catania, Catania , Italy
2 International Research Center on Periodontal and Systemic Health “PerioHealth”, University of Catania, Catania , Italy
3 Department of Clinical Specialistic and Dental Sciences, Marche Polytechnic University, Ancona , Italy
4 Department of Clinical Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia , Italy
†These authors contributed equally to this work.
Received: 26 June 2026 | Revised: 12 August 2026 | Accepted: 25 August 2026 | Published online: 7 September 2026
© 2026 by the Author(s). This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution -Noncommercial 4.0 International License (CC-by the license) ( https://creativecommons.org/licenses/by-nc/4.0/ )
Abstract

Artificial intelligence (AI) is increasingly presented as a transformative technology for periodontology, particularly for radiographic bone-loss detection, risk stratification, and personalized follow-up. Yet high performance in retrospective datasets should not be confused with clinical benefit. This Commentary argues that the field should move from celebrating algorithmic accuracy to demonstrating dependable, equitable, and useful decision support in real periodontal workflows. AI should augment—not replace—clinical examination, professional judgment, and patient communication. Priority should be given to representative multicenter datasets, external and prospective validation, interpretable outputs, privacy-preserving data governance, and evaluation of patient-relevant outcomes. The most credible near-term role for AI is therefore a supervised second reader and monitoring aid. Responsible adoption will depend less on increasingly complex models than on transparent evidence, accountable implementation, and sustained clinician oversight.

Keywords
Artificial intelligence
Periodontitis
Periodontal diagnosis
Clinical decision support
External validation
Ethics
Funding
This work was funded by the Italian Ministry of Health (grant PNRR-POC-2023-12377354) granted to G.I. This work was also supported by the European Union’s NextGenerationEU initiative under the Italian Ministry of University and Research as part of the PNRR—M4C2-I1.3 Project PE00000019 “HEAL ITALIA,” CUP I53C22001440006, awarded to A.P.
Conflict of interest
Both Alessandro Polizzi and Gaetano Isola are the Editorial Board Members of this journal, but they were not in any way involved in the editorial and peer-review process conducted for this paper, directly or indirectly. The authors declare no conflicts of interest.
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Eurasian Journal of Medicine and Oncology, Electronic ISSN: 2587-196X Print ISSN: 2587-2400, Published by AccScience Publishing