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REVIEW ARTICLE

Microbial challenges from tooth surface to implant damage: A review

Sura Dakhil Jassim1* ,  Fatima Malik Abood2 ,  Anfal Ihsan Jasim2
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1 Department of Periodontology, Faculty of Dentistry, University of Babylon, Babylon, Iraq
2 Department of Microbiology, Faculty of Dentistry, University of Babylon, Babylon, Iraq
EJMO, 6770 https://doi.org/10.36922/ejmo.6770
Submitted: 30 November 2024 | Revised: 5 January 2025 | Accepted: 5 February 2025 | Published: 21 February 2025
© 2025 by the Author(s). This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution -Noncommercial 4.0 International License (CC-by the license) ( https://creativecommons.org/licenses/by-nc/4.0/ )
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Abstract

Dental implants have become a common dental practice that dentists encounter daily in clinical settings. With this widespread use, peri-implant diseases have also become increasingly prevalent. Similar to periodontitis in natural teeth, peri-implant diseases are primarily caused by microorganisms, which are also referred to as peri-implant pathogens. This causal relationship forms the foundation of our review. This article provides an overview of peri-implant diseases, examines the microbial profile around implant surfaces in both healthy and diseased states, and compares this profile to that of natural teeth. A review of several studies on the microbial profile of dental implants indicates that key periodontal pathogens, including species from the red complex and Aggregatibacter actinomycetemcomitans, are frequently detected at high percentages in cases of peri-implantitis. However, peri-implantitis is also associated with microorganisms not typically linked to periodontitis. Despite the evident similarities between the microflora of dental implants and natural teeth, it remains premature to conclude that peri-implantitis and periodontitis share an identical microbial profile.

Keywords
Dental implants
Peri-implant diseases
Microbial challenge
Periodontitis
Funding
None.
Conflict of interest
The authors declared that there are no conflicts of interest from this study.
References
  1. Berglundh T, Armitage G, Araujo MG, et al. Peri-implant diseases and conditions: Consensus report of workgroup 4 of the 2017 worldworkshop on the classification of periodontal and peri-implant diseases and conditions. J Periodontol. 2018;89(Suppl 1):S313-S318. doi: 10.1111/jcpe.12957

 

  1. Lang NP, Berglundh T, Working Group 4 of Seventh European Workshop on Periodontology. Periimplant diseases: Where are we now?--Consensus of the Seventh European workshop on periodontology. J Clin Periodontol. 2011;38 Suppl 11:178-181. doi: 10.1111/j.1600-051X.2010.01674.x

 

  1. Meffert RM. Research in implantology at Louisiana State University School of Dentistry. Int J Oral Implantol. 1990;6:15-21.

 

  1. Andreiotelli M, Koutayas SO, Madianos PN, Strub JR. Relationship between interleukin-1 genotype and peri-implantitis: A literature review. Quintessence Int. 2008;39:289-298.

 

  1. Serino G, Strom C. Peri-implantitis in partially edentulous patients: Association with inadequate plaque control. Clin Oral Implants Res. 2009;20:169-174. doi: 10.1111/j.1600-0501.2008.01627.x

 

  1. Zarb G, Koka S, Albrektsson T. Hyperbole, clinical dissonance, and scratching the surface: Complication or disease? Int J Prosthodont. 2013;26:311.

 

  1. De Araújo Nobre M, Capelas C, Alves A, et al. Non-surgical treatment of peri-implant pathology. Int J Dent Hyg. 2006;4:84-90. doi: 10.1111/j.1601-5037.2006.00173.x

 

  1. Becker ST, Beck-Broichsitter BE, Graetz C, DeOrfer CE, Wiltfang J, Heasler R. Peri-implantitis versus periodontitis: functional differences indicated by transcriptome profiling. Clin Implant Dent Relat Res. 2014;16:401-411. doi: 10.1111/cid.12001

 

  1. Carcuac O, Berglundh T. Composition of human peri-implantitis and periodontal lesions. J Dent Res. 2014;93:1083-1088. doi: 10.1177/0022034514551754

 

  1. Albrektsson T, Dahlin C, Jemt T, Sennerby L, Turri A, Wenneberg A. Is marginal bone loss around oral implants the result of a provoked foreign body reaction? Clin Implant Dent Relat Res. 2014;16:155-165. doi: 10.1111/cid.12142

 

  1. Trindade R, Albrektsson T, Tengvall P, Wenneberg A. Foreign body reaction to biomaterials: On mechanisms for buildup and breakdown of osseointegration. Clin Implant Dent Relat Res. 2016;18:192-203. doi: 10.1111/cid.12274

 

  1. Qian J, Wennerberg A, Albrektsson T. Reasons for marginal bone loss around oral implants. Clin Implant Dent Relat Res. 2012;14:792-807. doi: 10.1111/cid.12014

 

  1. Rosenberg ES, Torosian JP, Slots J. Microbial differences in 2 clinically distinct types of failures of osseointegrated implants. Clin Oral Implants Res. 1991;2:135-144. doi: 10.1034/j.1600-0501.1991.020306.x

 

  1. Piattelli A, Scarano A, Piattelli M. Histologic observations on 230 retrieved dental implants: 8 years’ experience (1989–1996). J Periodontol. 1998;69:178-184. doi: 10.1902/jop.1998.69.2.178

 

  1. Ong ES, Newman HN, Wilson M. The occurrence of related-related microorganisms in relation to titanium implants. J Periodontol. 1992;63:200-205. doi: 10.1902/jop.1992.63.3.200

 

  1. Jassim SD, Abood FM. Isolation and identification of Aggregatibacter actinomycetemcomitans bacteria by culturing and polymerase chain reaction methods in patients with chronic periodontitis. Indian J Public Health Res Dev. 2018;9(10):482-487. doi: 10.5958/0976-5506.2018.01391.8

 

  1. Furst MM, Salvi GE, Lang NP, Persson GR. Bacterial colonization immediately after installation on oral titanium implants. Clin Oral Implants Res. 2007;18:501-508. doi: 10.1111/j.1600-0501.2007.01381.x

 

  1. Edgerton M, Lo SE, Scannapieco FA. Experimental salivary pellicles formed on titanium surfaces mediate adhesion of streptococci. Int J Oral Maxillofacial Implants. 1996;11:443-449.

 

  1. Socransky SS, Haffajee AD. Periodontal microbial ecology. Periodontology 2000. 2005;38:135-187. doi: 10.1111/j.1600-0757.2005.00107.x

 

  1. Kolenbrander PE, Palmer RJ Jr., Rickard AH, et al. Bacterial interactions and successions during plaque development. Periodontology 2000. 2006;42:47-79. doi: 10.1111/j.1600-0757.2006.00187.x

 

  1. Guilhen C, Forestier C, Balestrino D. Biofilm dispersal: Multiple elaborate strategies for dissemination of bacteria with unique properties. Mol Microbiol. 2017;105:188-210. doi: 10.1111/mmi.13698

 

  1. Rams TE, Link CC Jr. Microbiology of failing dental implants in humans: Electron microscopic observations. J Oral Implantol. 1983;11:93-100.

 

  1. Rams TE, Roberts TW, Tatum H Jr., Keyes PH. The subgingival microbial flora associated with human dental implants. J Prosthet Dent. 1984;51:529-534. doi: 10.1016/0022-3913(84)90309-3

 

  1. Apaza-Bedoya K, Tarce M, Benfatti CAM, et al. Synergistic interactions between corrosion and wear at titanium-based dental implant connections: A scoping review. J Periodontal Res. 2017;52(6):946-954. doi: 10.1111/jre.12469

 

  1. Pettersson M, Kelk P, Belibasakis GN, Bylund D, MolinThoren M, Johansson A. Titanium ions form particles that activate and execute interleukin- 1beta release from lipopolysaccharide-primed macrophages. J Periodontal Res. 2017;52(1):21-32. doi: 10.1111/jre.12364

 

  1. Quirynen M, Bollen CM. The influence of surface roughness and surface-free energy on supra- and subgingival plaque formation in man. A review of the literature. J Clin Periodontol. 1995;22(1):1-14. doi: 10.1111/j.1600-051x.1995.tb01765.x

 

  1. Roehling S, Astasov-Frauenhoffer M, Hauser-Gerspach I, et al. In vitro biofilm formation on titanium and zirconia implant surfaces. J Periodontol. 2017;88(3):298-307. doi: 10.1902/jop.2016.160245

 

  1. Guerra E, Pereira C, Faria R, Jorge AO, Bottino MA, de Melo RM. The impact of conical and nonconical abutments on bacterial infiltration at the implant-abutment interface. Int J Periodontics Restorative Dent. 2016;36:825-831. doi: 10.11607/prd.2779

 

  1. Mencio F, De Angelis P, Papi D, Rosella G, Pompa S, Di Carlo S. A randomized clinical trial about presence of pathogenic microflora and risk of peri-implantitis: Comparison of two different types of implant-abutment connections. Eur Rev Med Pharmacol Sci. 2017;21:1443-1451.

 

  1. Penarrocha‐Oltra D, Monreal‐Bello A, Penarrocha‐ Diago M, Alonso‐Perez‐Barquero J, Botticelli D, Canullo L. Microbial colonization of the peri-implant sulcus and implant connection of implants restored with cemented versus screw‐retained superstructures: A cross-sectional study. J Periodontol. 2016;87(9):1002-1011. doi: 10.1902/jop.2016.160017

 

  1. Souza JGS, Costa Oliveira BE, Bertolini M, Lima CV, Retamal-Valdes B, de Faveri M. Titanium particles and ions favor dysbiosis in oral biofilms. J Periodontal Res. 2020;55(2):258-266.

 

  1. Jones N, Ray B, Ranjit KT, Manna AC. Antibacterial activity of ZnO nanoparticle suspensions on a broad spectrum of microorganisms. FEMS Microbiol Lett. 2008;279(1):71-76. doi: 10.1111/j.1574-6968.2007.01012.x

 

  1. Yin L, Nakanishi Y, Alao AR, Song XF, Abduo J, Zhang Y. A review of engineered zirconia surfaces in biomedical applications. Procedia CIRP. 2017;65:284-290.

 

  1. Yao L, Wu X, Wu S, et al. Atomic layer deposition of zinc oxide on microrough zirconia to enhance osteogenesis and antibiosis. Ceram Int. 2019;45(18):24757-24767. doi: 10.1016/j.ceramint.2019.08.216

 

  1. Yamada R, Nozaki K, Horiuchi N, et al. Ag nanoparticle-coated zirconia for antibacterial prosthesis. Mater Sci Eng C Mater Biol Appl. 2017;78:1054-1060. doi: 10.1016/j.msec.2017.04.149

 

  1. Scarano A, Piattelli M, Caputi S, Favero GA, Piattelli A. Bacterial adhesion oncommercially pure titanium and zirconium oxide disks: An in vivo human study. J Periodontol. 2004;75(2):292-296. doi: 10.1902/jop.2004.75.2.292

 

  1. Grossner-Schreiber B, Teichmann J, Hannig M, Dorfer C, Wenderoth DF, Ott SJ. Modified implant surfaces show different biofilm compositions under in vivo conditions. Clin Oral Implants Res. 2009;20(8):817-826. doi: 10.1111/j.1600-0501.2009.01729.x

 

  1. van Brakel R, Cune MS, van Winkelhoff AJ, de Putter C, Verhoeven JW, van der Reijden W. Early bacterial colonization and soft tissue health around zirconia and titanium abutments: An in vivo study in man. Clin Oral Implants Res. 2011;22(6):571-577. doi: 10.1111/j.1600-0501.2010.02005.x

 

  1. Egawa M, Miura T, Kato T, Saito A, Yoshinari M. In vitro adherence of periodontopathic bacteria to zirconia and titanium surfaces. Dent Mater J. 2013;32(1):101-106. doi: 10.4012/dmj.2012-156

 

  1. Jo Y, Kim YT, Cho H, Ji MK, Heo J, Lim HP. Atomic layer deposition of ZrO2 on titanium inhibits bacterial adhesion and enhances osteoblast viability. Int J Nanomedicine. 2021;24(16):1509-1523. doi: 10.2147/IJN.S298449

 

  1. Morena D, Leitão-Almeida B, Pereira M, et al. Comparative clinical behavior of zirconia versus titanium dental implants: A systematic review and meta-analysis of randomized controlled trials. J Clin Med. 2024;13(15):4488. doi: 10.3390/jcm13154488

 

  1. Alves CH, Russi CL, Rocha NC, et al. Hostmicrobiome interactions regarding periimplantitis and dental implant loss. J Transl Med. 2022;20:425-436. doi: 10.1186/s12967-022-03636-9

 

  1. Camargo SEA, Xia X, Fares C, Ren F, Hsu SM, Budei D. Nanostructured surfaces to promote osteoblast proliferation and minimize bacterial adhesion on titanium. Materials (Basel). 2021;14(16):4357-4368. doi: 10.3390/ma14164357

 

  1. Bright R, Hayles A, Fernandes D, Visalakshan RM, Ninan N, Palms D. In vitro bactericidal efficacy of nanostructured Ti6Al4V surfaces is bacterial load dependent. ACS Appl Mater Interfaces. 2021;13(32):38007-38017. doi: 10.1021/acsami.1c06919

 

  1. Cooper LF, Zhou Y, Takebe J, et al. Fluoride modification effects on osteoblast behavior and bone formation at TiO2 grit-blasted c.p. titanium endosseous implants. Biomaterials. 2006;27(6):926-936. doi: 10.1016/j.biomaterials.2005.07.009

 

  1. Ouyang L, Zhao Y, Jin G, et al. Influence of sulfur content on bone formation and antibacterial ability of sulfonated PEEK. Biomaterials. 2016;83:115-126. doi: 10.1016/j.biomaterials.2016.01.017

 

  1. Sakka S, Baroudi K, Nassani MZ. Factors associated with early and late failure of dental implants. J Invest Clin Dent. 2012;3(4):258-261. doi: 10.1111/j.2041-1626.2012.00162.x

 

  1. Korsch M, Marten SM, Stoll D, Prechtl C, Dötsch A. Microbiological findings in early and late implant loss: An observational clinical casecontrolled study. BMC Oral Health. 2021;21:112-123. doi: 10.1186/s12903-021-01439-w

 

  1. Zitzmann NU, Berglundh T, Marinello CP, Lindhe J. Experimental peri-implant mucositis in man. J Clin Periodontol. 2001;28:517-523. doi: 10.1034/j.1600-051x.2001.028006517.x

 

  1. Takanashi K, Kishi M, Okuda K, Ishihara K. Colonization by Porphyromonas gingivalis and P. intermedia from teeth to osseointegrated implant regions. Bull Tokyo Dent Coll. 2004;45:77-85. doi: 10.2209/tdcpublication.45.77

 

  1. Quirynen M, Vogels R, Pauwels M, et al. Initial subgingival colonization of “pristine” pockets. J Dent Res. 2005;84:340-344. doi: 10.1177/154405910508400409

 

  1. Papaioannou W, Quirynen M, Nys M, van Steenberghe D. The effect of periodontal parameters on the subgingival microbiota around implants. Clin Oral Implants Res. 1995;6:197-204. doi: 10.1034/j.1600-0501.1995.060401.x

 

  1. Sbordone L, Barone A, Ciaglia RN, Ramaglia L, Iacono VJ. Longitudinal study of dental implants in a periodontally compromised population. J Periodontol. 1999;70:1322-1329. doi: 10.1902/jop.1999.70.11.1322

 

  1. Belibasakis GN, Charalampakis G, Bostanci N, Stadlinger B. Peri-implant infections of oral biofilm etiology. Adv Exp Med Biol. 2015;830:69-84. doi: 10.1007/978-3-319-11038-7_4

 

  1. Danser MM, van Winkelhoff AJ, de Graaff J, van der Velden U. Putative periodontal pathogens colonizing oral mucous membranes in denture-wearing subjects with a past history of periodontitis. J Clin Periodontol. 1995;22:854-859. doi: 10.1111/j.1600-051x.1995.tb01784.x

 

  1. Danser MM, van Winkelhoff AJ, van der Velden U. Periodontal bacteria colonizing oral mucous membranes in edentulous patients wearing dental implants. J Periodontol. 1997;68:209-216. doi: 10.1902/jop.1997.68.3.209

 

  1. Van Assche N, Van Essche M, Pauwels M, Teughels W, Quirynen M. Do periodontopathogens disappear after fullmouth tooth extraction? J Clin Periodontol. 2009;36:1043-1047. doi: 10.1111/j.1600-051X.2009.01477.x

 

  1. Quirynen M, Van Assche N. Microbial changes after full-mouth tooth extraction, followed by 2-stage implant placement. J Clin Periodontol. 2011;38:581-589. doi: 10.1111/j.1600-051X.2011.01728.x

 

  1. Casado PL, Otazu IB, Balduino A, de Mello W, Barboza EP, Duarte EML. Identification of periodontal pathogens in healthy periimplant sites. Implant Dent. 2011;20:226-235. doi: 10.1097/ID.0b013e3182199348

 

  1. Canullo L, Pe-arrocha-Oltra D, Covani U, Botticelli D, Serino G, Penarrocha M. Clinical and microbiological findings in patients with peri-implantitis: A cross-sectional study. Clin Oral Implants Res. 2016;27(3):376-382. doi: 10.1111/clr.12557

 

  1. Heitz-Mayfield LJA, Salvi GE. Peri-implant mucositis. J Clin Periodontol. 2018;45(20):237-245. doi: 10.1111/jcpe.12953

 

  1. Persson GR, Samuelsson E, Lindahl C, Renvert S. Mechanical non-surgical treatment of peri‐implantitis: A single blinded randomized longitudinal clinical study. II. Microbiological results. J Clin Periodontol. 2010;37:563-573. doi: 10.1111/j.1600-051X.2010.01561.x

 

  1. Schwarz F, Becker K, Rahn S, Hegewald A, Pfeffer K, Henrich B. Real-time PCR analysis of fungal organisms and bacterial species at peri-implantitis sites. Int J Implant Dent. 2015;1:9. doi: 10.1186/s40729-015-0010-6

 

  1. Shibli JA, Melo L, Ferrari DS, Figueiredo LC, Faveri M, Feres M. Composition of supra- and subgingival biofilm of subjects with healthy and diseased implants. Clin OralImplants Res. 2008;19(10):975-982. doi: 10.1111/j.1600-0501.2008.01566.x

 

  1. Harris LG, Mead L, Muller-Oberlander E, Richards RG. Bacteria and cell cytocompatibility studies on coated medical grade titanium surfaces. J Biomed Mater Res A. 2006;78:50-58. doi: 10.1002/jbm.a.30611

 

  1. Jenkinson HF, Lamont RJ. Oral microbial ecology. In: Lamont RJ, editor. Oral Microbiology and Immunology. Washington, D.C: ASM Press; 2006.

 

  1. Friedlander AH. Oral cavity Staphylococci are a potential source of prosthetic joint infection. Clin Infect Dis. 2010;50:1682-1683. doi: 10.1086/653003

 

  1. Arciola CR, Visai L, Testoni F, et al. Concise survey of Staphylococcus aureus virulence factors that promote adhesion and damage to peri-implant tissues Int J Artif Organs. 2011;34:771-780. doi: 10.5301/ijao.5000046

 

  1. Van Assche N, Pittayapat P, Jacobs R, Pauwels M, Teughels W, Quirynen M. Microbiological outcome of two screw-shaped titanium implant systems placed following a split-mouth randomized protocol, at the 12th year of follow-up after loading. Eur J Oral Implantol. 2011;4:103-116.

 

  1. Tsigarida AA, Dabdoub SM, Nagaraja HN, Kumar PS. The influence of smoking on the peri-implant microbiome. J Dent Res. 2015;94(9):1202-1217. doi: 10.1177/0022034515590581

 

  1. Rutar A, Lang NP, Buser D, Burgin W, Mombelli A. Retrospective assessment of clinical and microbiological factors affecting periimplant tissue conditions. Clin Oral Implants Res. 2001;12:189-195. doi: 10.1034/j.1600-0501.2001.012003189.x

 

  1. Jankovic S, Aleksic Z, Dimitrijevic B, Lekovic V, Camargo P, Kenney B. Prevalence of human cytomegalovirus and Epstein-Barr virus in subgingival plaque at peri-implantitis, mucositis and healthy sites. A pilot study. Int J Oral Maxillofac Surg. 2011;40:271-276. doi: 10.1016/j.ijom.2010.11.004

 

  1. Jankovic S, Aleksic Z, Dimitrijevic B, Lekovic V, Milinkovic I, Kenney B. Correlation between different genotypes of human cytomegalovirus and Epstein-Barr virus and peri-implant tissue status. Aust Dent J. 2011;56:382-388. doi: 10.1111/j.1834-7819.2011.01360.x

 

  1. Rakic M, Grusovin MG, Canullo L. The microbiologic profile associated with peri-implantitis in humans: A systematic review. Int J Oral Maxillofac Implant. 2016;31:359-368. doi: 10.11607/jomi.4150

 

  1. Lekholm U, Adell R, Lindhe J, et al. Marginal tissue reactions at osseointegrated titanium fixtures: (II) A cross-sectional retrospective study. Int J Oral Maxillofac Surg. 1986;15(1):53-61. doi: 10.1016/s0300-9785(86)80011-4

 

  1. Koyanagi T, Sakamoto M, Takeuchi Y, Ohkuma M, Izumi Y. Analysis of microbiota associated with periimplantitis using 16 s rRNA gene clone library. J Oral Microbiol. 2010;2:5104-5111. doi: 10.3402/jom.v2i0.5104

 

  1. Cavalcanti YW, Wilson M, Lewis M, Del-Bel-Cury AA, da Silva WJ, Williams DW. Modulation of Candida albicans virulence by bacterial biofilms on titanium surfaces. Biofouling. 2016;32(2):123-134. doi: 10.1080/08927014.2015.1125472

 

  1. Rosa EAR, Rached RN, Ignácio SA, et al. Phenotypic evaluation of the effect of anaerobiosis on some virulence attributes of Candida albicans. J Med Microbiol. 2008;57(10):1277-1281. doi: 10.1099/jmm.0.2008/001107-0

 

  1. Embery G, Waddington RJ, Hall RC, Last KS. Connective tissue elements as diagnostic aids in periodontology. Periodontol 2000. 2000;24(1):193-214. doi: 10.1034/j.1600-0757.2000.2240109.x

 

  1. Canabarro A, Valle C, Farias MR, Santos FB, Lazera M, Wanke B. Association of subgingival colonization of Candida albicans and other yeasts with severity of chronic periodontitis. J Periodontol Res. 2013;48(4):428-432. doi: 10.1111/jre.12022

 

  1. Quirynen M, Vogels R, Peeters W, van Steenberghe D, Naert I, Haffajee A. Dynamics of initial subgingival colonization of “pristine” peri-implant pockets. Clin Oral Implants Res. 2006;17(1):25-37. doi: 10.1111/j.1600-0501.2005.01194.x

 

  1. Kumar PS. Systemic risk factors for the development of periimplant diseases. Implant Dent. 2019;28(2):115-119. doi: 10.1097/ID.0000000000000873

 

  1. Kordbacheh Changi K, Finkelstein J, Papapanou PN. Peri-implantitis prevalence, incidence rate, and risk factors: A study of electronic health records at a U.S. dental school. Clin Oral Implants Res. 2019;30(4):306-314. doi: 10.1111/clr.13416

 

  1. Martinez-Amargant J, de Tapia B, Pascual A, et al. Association between smoking and peri-implant diseases: A retrospective study. Clin Oral Implants Res. 2023;34(10):1127-1140. doi: 10.1111/clr.14147

 

  1. Subbiahdoss G, Kuijer R, Grijpma DW, van der Mei HC, Busscher HJ. Microbial biofilm growth vs. tissue integration: The race for the surface experimentally studied. Acta Biomater. 2009;5(5):1399-1404. doi: 10.1016/j.actbio.2008.12.011

 

  1. Gristina AG. Biomaterial-centered infection: microbial adhesion versus tissue integration. Science. 1987;237(4822):1588-1595. doi: 10.1126/science.3629258

 

  1. Lumbikananda S, Srithanyarat SS, Mattheos N, Osathanon T. Oral fluid biomarkers for peri-implantitis: A scoping review. Int Dent J. 2024;74(3):387-402. doi: 10.1016/j.identj.2023.11.005

 

  1. Rams TE, Degener JE, van Winkelho AJ. Antibiotic resistance in human peri-implantitis microbiota. Clin Oral Implant Res. 2014;25:82-90. doi: 10.1111/clr.12160

 

  1. Diefenbeck M, Schrader C, Gras F, et al. Gentamicin coating of plasma chemical oxidized Titanium alloy prevents implant-related osteomyelitis in rats. Biomaterials. 2016;101:156-164. doi: 10.1016/j.biomaterials.2016.05.039

 

  1. Suchý T, Vištejnová L, Šupová M, et al. Vancomycin-loaded collagen/hydroxyapatite layers electrospun on 3D printed titanium implants prevent bone destruction associated with S. epidermidis infection and enhance osseointegration. Biomedicines. 2021;9(5):531. doi: 10.3390/biomedicines9050531

 

  1. Xi W, Hegde V, Zoller SD, et al. Point-of-care antimicrobial coating protects orthopaedic implants from bacterial challenge. Nat Commun. 2021;12:5473-5488. doi: 10.1038/s41467-021-25383-z

 

  1. Zarghami V, Ghorbani M, Pooshang Bagheri K, Shokrgozar MA. Melittin antimicrobial peptide thin layer on bone implant chitosan-antibiotic coatings and their bactericidal properties. Mater Chem Phys. 2021;263:124432. doi: 10.1007/s10856-022-06666-3

 

  1. Mulla M, Mulla M, Hegde S, Koshy AV. In vitro assessment of the effect of probiotic lactobacillus reuteri on peri-implantitis microflora. BMC Oral Health. 2021;21(1):408. doi: 10.1186/s12903-021-01762-2

 

  1. Vacca C, Contu MP, Rossi C, et al. In vitro interactions between Streptococcus intermedius and Streptococcus salivarius K12 on a titanium cylindrical surface. Pathogens. 2020;9(12):1069. doi: 10.3390/pathogens9121069

 

  1. Gomes GH, Misawa MYO, Fernandes C, et al. A systematic review and meta-analysis of the survival rate of implants placed in previously failed sites. Braz Oral Res. 2018;32:e27. doi: 10.1590/1807-3107bor-2018.vol32.0027

 

  1. Montoya-Salazar V, Castillo-Oyague R, Torres-Sanchez C, Lynch CD, Gutierrez-Perez JL, Torres-Lagares D. Outcome of single immediate implants placed in post-extraction infected and non-infected sites, restored with cemented crowns: A 3-year prospective study. J Dent. 2014;42:645-652. doi: 10.1016/j.jdent.2014.03.008

 

  1. Chrcanovic BR, Martins MD, Wennerberg A. Immediate placement of implants into infected sites: A systematic review. Clin Implant Dent Relat Res. 2015;17(Suppl 1):e1-16. doi: 10.1111/cid.12098

 

  1. Anitua E, Pinas L, Begona L, Alkhraisat MH. Prognosis of dental implants immediately placed in sockets affected by peri-implantitis: A retrospective pilot study. Int J Periodontics Restorative Dent. 2017;37:713-719. doi: 10.11607/prd.2458
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