AccScience Publishing / EJMO / Volume 6 / Issue 2 / DOI: 10.14744/ejmo.2022.26330
CASE REPORT

Varicella-Zoster Virus Infection and Brivudine Therapy: Unexpected Response in Sarcoma Patient

Osman Köstek1 Murat Sarı1 İbrahim Vedat Bayoğlu1
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1 Department of Medical Oncology, Marmara University, Faculty of Medicine, İstanbul, Turkey
EJMO 2022, 6(2), 182–185; https://doi.org/10.14744/ejmo.2022.26330
Submitted: 1 February 2022 | Accepted: 9 May 2022 | Published: 6 June 2022
© 2022 by the Author(s). This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution -Noncommercial 4.0 International License (CC-by the license) ( https://creativecommons.org/licenses/by-nc/4.0/ )
Abstract

Soft tissue sarcoma is a heterogeneous disease and treatment options are limited in advanced stage settings. Brivudine is a thymidine-nucleoside analog and inhibits DNA polymerase in VZV infection. We demonstrated a case of a patient who was diagnosed with both VZV infection and advanced stage sarcoma, and unexpected anti-tumoral response after brivudine therapy. 

Keywords
VZV-infection
brivudine
undifferentiated pleomorphic sarcoma
anti-tumoral response
Conflict of interest
The authors declare that there is no conflict of interest that could be perceived as prejudicing the impartiality of the present study. The present study did not receive any funding.
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Eurasian Journal of Medicine and Oncology, Electronic ISSN: 2587-196X Print ISSN: 2587-2400, Published by AccScience Publishing