AccScience Publishing / EJMO / Volume 1 / Issue 3 / DOI: 10.14744/ejmo.2017.65365
RESEARCH ARTICLE

Gastric Cancer Patients with Bone Marrow Metastasis: A Single-Center Experience and Review of the Literature

Yakup Ergun1 Dogan Uncu1 Ozan Yazıcı1 Gokhan Ucar1 Ekin Konca Karabuga2 Nurullah Zengin1
EJMO 2017, 1(3), 160–163; https://doi.org/10.14744/ejmo.2017.65365
Submitted: 24 August 2017 | Accepted: 25 September 2017 | Published: 29 September 2017
© 2017 by the Author(s). This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution -Noncommercial 4.0 International License (CC-by the license) ( https://creativecommons.org/licenses/by-nc/4.0/ )
Abstract

Objectives: The purpose of this study is to investigate bone marrow metastasis in patients with Gastric cancer.

Methods: We retrospectively evaluated patients with gastric cancer who applied to our clinic between 2010-2016.

Results: 896 patients with gastric cancer were included in the study. Patients had metastatic bone marrow in 8 patients. When the laboratory results were evaluated; in 5 patients trombocytopenia with anemia were present, 2 patients had only tromboscytopenia, one patient had only anemia. In all patients white blood cell count was within normal range. The median survival of the 8 patients in our study was 72 days. In our chemoteraphy group (6 patients) median survival was 77 days (range, 49 to 145 days), in the non-treatment group was 7,5 days (range, 3 to 12 days).

Conclusion: Gastric cancer with bone marrow metastasis is usually seen in younger patients, and is related to poorly differantiated subtypes and is a disease with worse prognosis. Median survival with paliative chemotraphy is under 3 months.

Keywords
Bone marrow metastasis
gastric cancer
signet ring cell
Conflict of interest
None declared.
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Eurasian Journal of Medicine and Oncology, Electronic ISSN: 2587-196X Print ISSN: 2587-2400, Published by AccScience Publishing