Clinical Characteristics of Patients with Colon Cancer
Background: Colon cancer is the third leading cause of cancer morbidity and mortality in the world. Objectives: To investigate the clinical characteristics of patients with colon cancer. Methods: A cross-sectional descriptive study was used to analyze the characteristics of colon cancer patients in the Service of General Surgery of Military Hospital Octavio de la Concepción y la Pedraja from October 2013 to August 2017. The universe consisted of 61 patients with colon cancer. Results: The study was mainly female, and the patients over 60 years old accounted for the majority, especially the patients in the age group of 70–79 years old. Villous adenoma was the most common history. Low gastrointestinal bleeding was the main manifestation of left tumor patients. Most cancers were well differentiated. Adenocarcinoma was the most common histological type. Conclusion: Villous adenoma was the main pathological history of women aged 70–79. Lower gastrointestinal bleeding was the most common clinical manifestation, which was related to left position. Some patients need surgical treatment, and the most commonly used technique was left hemicolectomy. Most tumors were well differentiated with chronic inflammation.
Zhu H, Zhang G, Yi X, et al., 2015, Histology Subtypes and Polyp Size are Associated with Synchronous Colorectal Carcinoma of Colorectal Serrated Polyps: A Study of 499 Serrated Polyps. Am J Cancer Res, 5:363–74.
Zhou L, Xie J, Gu L, et al., 2015, Common Genetic Variant on BMP4 Contributes to Colorectal Adenoma and Cancer: A Metaanalysis Based on 15 Studies. Cytokinin, 72:154–9. DOI: 10.1016/j.cyto.2014.12.021.
Xie J, Dong H, Chen H, et al., 2015, Exploring Cancer Metastasis Prevention Strategy: Interrupting Adhesion of Cancer Cells to Vascular Endothelia of Potential Metastatic Tissues by Antibody-coated Nanomaterial. J Nanobiotechnology, 13:9. DOI: 10.1186/s12951-015-0072-x.
Vrinten C, Waller J, Von WC, et al., 2015, Cancer Fear: Facilitator and Deterrent to Participation in Colorectal Cancer Screening. Can Epidemiol Biom Prev, 24:400–5. DOI: 10.1158/1055-9965.EPI-14-0967.
Tanday S, 2015, Less Surgery Improves Survival for Advanced Colorectal Cancer. Lancet Tumor, 16. DOI: 10.1016/S1470-2045(14)71202-1.
Tamandl D, Butte JM, Allen PJ, et al., 2015, Hospital Readmissions after Liver Surgery for Metastatic Colorectal Cancer. Surgery, 157:231–8. DOI: 10.1016/j.surg.2014.09.016.
Bachmayr-Heyda A, Reiner AT, Auer K, et al., 2015, Correlation of Circular RNA Abundance with Proliferation-exemplified with Colorectal and Ovarian Cancer, Idiopathic Lung Fibrosis, and Normal Human Tissues. Sci Rep, 5:8057. DOI: 10.1038/srep08057.
Choe EK, Park KJ, Chung SJ, et al., 2015, Colonoscopic Surveillance after Colorectal Cancer Resection: Who Needs More Intensive Follow-up? Digestion, 91:142–9. DOI: 10.1159/000370308.
Crncec I, Pathria P, Svinka J, et al., 2015, Induction of Colorectal Cancer in Mice and Histomorphometric Evaluation of Tumors. In: Eferl R, Casanova E (eds.) Mouse Models of Cancer. Methods in Molecular Biology, 1267. New York: Humana Press. DOI: 10.1007/978-1-4939-2297-0_7.
Sugano K, Maeda K, Ohtani H, et al., 2015, Expression of xCT as a Predictor of Disease Recurrence in Patients with Colorectal Cancer. Anticancer Res, 35:677–82.
Suenaga M, Mizunuma N, Shinozaki E, et al., 2015, Anticoagulant Therapy for Venous Thromboembolism Detected by Doppler Ultrasound in Patients with Metastatic Colorectal Cancer Receiving Bevacizumab. Onco Targets Ther, 8:243–9. DOI: 10.2147/OTT.S75722.
Sturludóttir M, Martling A, Carlsson S, et al., 2015, Synchronous Rectal and Prostate Cancer—The Impact of MRI on Incidence and Imaging Findings. European Radio, 84:563–7. DOI: 10.1016/j.ejrad.2014.12.030.
Ferreira Bohórquez EJ, Meléndez Héctor J, 2012, Características clínicas, demográficas e histopatológicas de los pacientes con cáncer colorectal del Hospital Universitario de Santander. Rev Colomb de Cir [Clinical, Demographic and Histopathological Features of Colorectal Cancer Patients in Santander University Hospital]. Reverend Columbus of Cir, 27:213–20.
Montes de Oca Megías E, Soler Porro LL, Noa Pedroso G, et al., 2012, Comportamiento del cáncer colorrectal esporádico en un hospital provincial [Behavior of Sporadic Colorectal Cancer in Provincial Hospitals]. Rev Cubana Med, 51.
Neuhouser ML, Cheng TY, Beresford SA, et al., 2015, Red Blood Cell Folate and Plasma Folate are not Associated with Risk of Incident Colorectal Cancer in the Women’s Health Initiative Observational Study. Int J Cancer, 137:930–9. DOI: 10.1002/ijc.29453.
Liu Z, Zhang Y, Franzin L, et al., 2015, Trends and Changes in the Incidence of Breast and Colorectal Cancer from 1995 to 2011: Comparative Study between Surveillance, Epidemiology and End Result Data from the Texas Cancer Registry and the National Cancer Institute. Int J Oncol, 46:1819–26. DOI: 10.3892/ijo.2015.2881.
Barrera E, Bannura CG, Illanes FF, et al., 2012, Resultados precoces de la cirugía electiva del cáncer de colon en mayores de 75 años [Early Results of Surgery for Colorectal Cancer Among Patients Aged 75 Years or More]. Rev Chil Cir, 64:63–7. DOI: 10.4067/S0718-40262012000100010.
Chacaltana Mendoza A, Rodriguez Ulloa C, Frisancho Velarde O, 2011, Valoración de las indicaciones de colonoscopía en la predicción diagnóstica de cáncer de colon [Assessment of the Indications of Colonoscopy in the Prediction of Colon Cancer Diagnosis]. Rev Gastroenterol, 31.
Juliao Baños F, Agudelo Zapata Y, Yepes Delgado C, et al., 2014, Variación en el cuidado de pacientes con Enfermedad Inflamatoria Intestinal (EII): resultado de una encuesta [Survey Results Regarding Variations in Care of Patients with Inflammatory Bowel Disease]. Rev Colomb Gastr, 29:11–8.
Ojima T, Nakamori M, Nakamura M, et al., 2015, Laparoscopic combined resection of synchronous gastric and colorectal cancer. Surg Laparosc Endosc Percutan Tech, 25.
Ling C, Wang L, Wang Z, et al., 2015, A pathway-centric survey of somatic mutations in chinese patients with colorectal carcinomas. PLoS One, 10:e0116753. DOI: 10.1371/journal.pone.0116753.
Loyde KJ De, Harrison JD, Durcinoska I, et al., 2015, Which Information Source is the Best? The Correlation between Patient Reports, Clinical Reports and Patient Comorbidity Medical Records and Adjuvant Treatment Health Information. Clinical Practice, 21:339–46. DOI: 10.1111/jep.12327.
Eng OS, Melstrom LG, Carpizo DR, 2015, The Relationship of Perioperative Fluid Administration to Outcomes in Colorectal and Pancreatic Surgery: A Review of the Literature. J Surg Oncol, 111: DOI: 10.1002/jso.23857.
Kingham TP, Correa-Gallego C, D’Angelica MI, et al., 2014, Hepatic Parenchymal Preservation Surgery: Decreasing Morbidity and Mortality Rates in 4,152 Resections for Malignancy. J Am Coll Surg, 220: 471–9. DOI: 10.1016/j.jamcollsurg.2014.12.026.
Malvezzi M, Bertuccio P, Rosso T, et al., 2015, European Cancer Mortality Predictions for the Year 2015: Does Lung Cancer Have the Highest Death Rate in EU Women? Ann Oncol, 26:779–86. DOI: 10.1093/annonc/mdv001.
Adams SA, Choi SK, Khang L, et al., 2015, Decreased Cancer Mortality-to-Incidence Ratios with Increased Accessibility of Federally Qualified Health Centers. J Community Health, 40:633–41. DOI: 10.1007/s10900-014-9978-8.
Hano García OM, Wood Rodríguez L, Galbán García E, et al., 2011, Factores de riesgo para el cáncer colorectal [Risk Factors for Colorectal Cancer]. Rev Cubana Med, 50.
Lynch HT, Snyder CL, Shaw TG, et al., 2015, Milestones of Lynch Syndrome: 1895–2015. Nat Rev Cancer, 15:181–94. DOI: 10.1038/nrc3878.
Larkey LK, McClain D, Roe DJ, et al., 2015, Randomized Controlled Trial of Storytelling Compared to a Personal Risk Tool Intervention on Colorectal Cancer Screening in Low-Income Patients. Am J Health Promot, 30:e59-70. DOI: 10.4278/ajhp.131111-QUAN-572.
Kwakman R, Cuba EM de, Winter JP de, et al., 2015, Tailoring Heated Intraperitoneal Mitomycin C for Peritoneal Metastases Originating from Colorectal Carcinoma: A Translation Method to Improve Survival. Br J Cancer, 112:851–6. DOI: 10.1038/bjc.2015.18.
Leake I, 2015, Combining Drug Therapies to Improve Treatment Efficacy in Metastatic Colorectal Cancer. Nat Rev Gastroenterol Hepatol, 12. DOI: 10.1038/nrgastro.2015.29.
Laskar RS, Talukdar FR, Choudhury JH, et al., 2015, Association of HPV with Genetic and Epigenetic Alterations in Colorectal Adenocarcinoma from Indian Population. Tumor Biol, 36:4661–70. DOI: 10.1007/s13277-015-3114-y.
Karel MJ, Mulligan EA, Walder A, et al., 2015, Valued Life Abilities among Veteran Cancer Survivors. Health Expect, 19:679–90. DOI: 10.1111/hex.12343.
Zanella ER, Galimi F, Sassi F, et al., 2015, IGF2 is an Actionable Target that Identifies a Distinct Subpopulation of Colorectal Cancer Patients with Marginal Response to Anti-EGFR Therapies. Sci Transl Med, 7. DOI: 10.1126/scitranslmed.3010445.
Ying J, Tsujii M, Kondo J, et al., 2015, The Effectiveness of an Antihuman IL-6 Receptor Monoclonal Antibody Combined with Chemotherapy to Target Colon Cancer Stem-like Cells. Int J Oncol, 46:1551–9. DOI: 10.3892/ijo.2015.2851.
Yin D, Liu Z, Zhang E, et al., 2015, Decreased Expression of Long Noncoding RNA MEG3 Affects Cell Proliferation and Predicts a Poor Prognosis in Patients with Colorectal Cancer. Tumor Biol, 36:4851–9. DOI: 10.1007/s13277-015-3139-2.
Wang L, Shen X, Wang Z, et al., 2015, A Molecular Signature for the Prediction of Recurrence in Colorectal Cancer. Mol Cancer, 14:22. DOI: 10.1186/s12943-015-0296-2.