AccScience Publishing / ARNM / Volume 1 / Issue 1 / DOI: 10.36922/arnm.0907
Submit to ARNM
Cite this article
59
Download
979
Views
Journal Browser
Volume | Year
Issue
Search
Forthcoming Issue
Current Issue
View All
News and Announcements
View All
REVIEW

Image-guided permanent I-125 seed implantation for refractory head-and-neck carcinoma in China: A comprehensive review of contemporary technical and clinical aspects

Suqing Tian1† ,  Bin Qiu1† ,  Ping Jiang1 ,  Yuliang Jiang1 ,  Zhe Ji1 ,  Mingwei Huang2 ,  Gordon L. Grado3 ,  Junjie Wang1*
Show Less
1 Department of Radiation Oncology, Peking University Third Hospital, Beijing, China
2 Department of Head and Neck, Peking University Stomatology Hospital, Beijing, China
3 Southwest Oncology Centers, Scottsdale, Arizona, USA
ARNM 2023, 1(1), 0907 https://doi.org/10.36922/arnm.0907
Submitted: 5 May 2023 | Accepted: 26 June 2023 | Published: 7 July 2023
© 2023 by the Author(s). This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution 4.0 International License ( https://creativecommons.org/licenses/by/4.0/ )
Download PDF
Cite
XML
Abstract

Permanent I-125 seed implantation is one of the most commonly used brachytherapy (BT) forms, potentially applicable to almost any solid tumor as a standalone anti-tumor therapy or in combination with external beam radiotherapy (EBRT). The main advantage of I-125 seed implantation BT is its ability to deliver a high radiation dose within target volumes while maintaining a sharp dose drop-off profile, thereby protecting adjacent normal tissue. The clinical use of I-125 seed implantation in China has significantly increased in the past decades due to the application of an image-guided BT treatment planning system with reverse optimization capabilities and 3D printing individual template (3D-PIT) assistance. Computed tomography-guided I-125 seed implantation became a widely common modality of BT and has been used in many clinical settings for a variety of refractory cancer in China since 2002. The application has been expanded significantly not only for prostate cancer as monotherapy but also in combination with EBRT for the salvage treatment for refractory/recurrent head-and-neck carcinoma (HNC). With the assistance of 3D-PIT, since 2015, the quality control of I-125 seed implantation has been significantly adapted with high precision and real-time dose optimization. This review aims to summarize the developments and status of 3D-PIT-based I-125 seed implantation BT for the treatment of refractory HNC and standardized workflow in China.

Keywords
Low-dose-rate
I-125 seed implantation
Refractory head-and-neck carcinoma
3D printed templates
Brachytherapy
Funding
Special fund of the National Clinical Key Specialty Construction Program, P. R. China (2021)
References
  1. Mody M, Rocco J, Yom S, et al., 2021. Head and neck cancer. Lancet, 398: 2289–2299.

 

  1. Chow LQM, 2020, Head and neck cancer. N Engl J Med, 382: 60–72. https://doi.org/10.1056/NEJMra1715715

 

  1. Cooper J, Zhang Q, Pajak T, et al., 2012, Long-term follow-up of the RTOG 9501/intergroup phase III trial: Postoperative concurrent radiation therapy and chemotherapy in high-risk squamous cell carcinoma of the head and neck. Int J Radiat Oncol Biol Phys, 84: 1198–1205. https://doi.org/10.1016/j.ijrobp.2012.05.008

 

  1. Brockstein B, Haraf D, Rademaker A, et al., 2004, Patterns of failure, prognostic factors and survival in locoregionally advanced head and neck cancer treated with concomitant chemoradiotherapy: A 9-year, 337-patient, multi-institutional experience. Ann Oncol, 15: 1179–1186. https://doi.org/10.1093/annonc/mdh308

 

  1. Cooper J, Pajak T, Rubin P, et al., 1989, Second malignancies in patients who have head and neck cancer: Incidence, effect on survival and implications based on the RTOG experience. Int J Radiat Oncol Biol Phys, 17: 449–456. https://doi.org/10.1016/0360-3016(89)90094-1

 

  1. Bachar G, Goh C, Goldstein D, et al., 2010, Long-term outcome analysis after surgical salvage for recurrent tonsil carcinoma following radical radiotherapy. Eur Arch Otorhinolaryngol, 267: 295–301. https://doi.org/10.1007/s00405-009-1070-0

 

  1. Kim YS, 2017, Reirradiation of head and neck cancer in the era of intensity-modulated radiotherapy: Patient selection, practical aspects, and current evidence. Radiat Oncol J, 35: 1–15. https://doi.org/10.3857/roj.2017.00122

 

  1. Garzotto M, Fair WR, 2000, Historical perspective on prostate brachytherapy. J Endourol, 14: 315–318. https://doi.org/10.1089/end.2000.14.315

 

  1. Polgár C, Major T, Fodor J, et al., 2010, Accelerated partial-breast irradiation using high-dose-rate interstitial brachytherapy: 12-year update of a prospective clinical study. Radiother Oncol, 94: 274–279. https://doi.org/10.1016/j.radonc.2010.01.019

 

  1. Bittner NHJ, Orio PFO 3rd, Merrick GS, et al., 2017, The American College of Radiology and the American Brachytherapy Society practice parameter for transperineal permanent brachytherapy of prostate cancer. Brachytherapy, 16: 59–67. https://doi.org/10.1016/j.brachy.2016.06.003

 

  1. Nag S, Erickson B, Thomadsen B, et al., 2000, The American Brachytherapy Society recommendations for high-dose-rate brachytherapy for carcinoma of the cervix. Int J Radiat Oncol Biol Phys, 48: 201–211. https://doi.org/10.1016/s0360-3016(00)00497-1

 

  1. Yue N, Dicker AP, Nath R, et al., 1999, The impact of edema on planning 125I and 103Pd prostate implants. Med Phys, 26: 763–767. https://doi.org/10.1118/1.598585

 

  1. Jiang P, Wang J, Ran W, et al., 2019, Five-year outcome of ultrasound-guided interstitial permanent (125)I seeds implantation for local head and neck recurrent tumors: A single center retrospective study. J Contemp Brachytherapy, 11: 28–34. https://doi.org/10.5114/jcb.2019.83336

 

  1. Ji Z, Jiang Y, Tian S, et al., 2019, The effectiveness and prognostic factors of CT-guided radioactive I-125 seed implantation for the treatment of recurrent head and neck cancer after external beam radiation therapy. Int J Radiat Oncol Biol Phys, 103: 638–645. https://doi.org/10.1016/j.ijrobp.2018.10.034

 

  1. Zhang GH, Lv XM, Wu WJ, et al., 2019, Evaluation of the accuracy of computer-assisted techniques in the interstitial brachytherapy of the deep regions of the head and neck. Brachytherapy, 18: 217–223. https://doi.org/10.1016/j.brachy.2018.12.003

 

  1. Jiang Y, Zhen P, Dai J, et al., 2021, Long-term safety and efficacy of CT-Guided I(125) radioactive seed implantation as a salvage therapy for recurrent head and neck squamous carcinoma: A multicenter retrospective study. Front Oncol, 11: 645077. https://doi.org/10.3389/fonc.2021.645077

 

  1. Jiang Y, Ji Z, Guo F, et al., 2018, Side effects of CT-guided implantation of (125)I seeds for recurrent malignant tumors of the head and neck assisted by 3D printing non co-planar template. Radiat Oncol, 13: 18. https://doi.org/10.1186/s13014-018-0959-4

 

  1. Huang MW, Zhang JG, Zheng L, et al., 2016, Accuracy evaluation of a 3D-printed individual template for needle guidance in head and neck brachytherapy. J Radiat Res, 57: 662–667. https://doi.org/10.1093/jrr/rrw033

 

  1. Tanderup K, Viswanathan A, Kirisits C, et al., 2014, Magnetic resonance image guided brachytherapy. Semin Radiat Oncol, 24: 181–191. https://doi.org/10.1016/j.semradonc.2014.02.007

 

  1. Zhang J, Zhang J, Song T, et al., 2008, I-125 seed implant brachytherapy-assisted surgery with preservation of the facial nerve for treatment of malignant parotid gland tumors. Int J Oral Maxillofac Surg, 37: 515–520. https://doi.org/10.1016/j.ijom.2008.04.013

 

  1. Huang M, Zhang J, Tong D, et al., 2012, Postoperative 125I brachytherapy delivered by digital model obturators for recurrent or locally advanced maxillary cancers. Laryngoscope, 122: 2461–2467. https://doi.org/10.1002/lary.23527

 

  1. Mao MH, Zheng L, Wang XM, et al., 2017, Surgery combined with postoperative I seed brachytherapy for the treatment of mucoepidermoid carcinoma of the parotid gland in pediatric patients. Pediatr Blood Cancer, 64: 57–63. https://doi.org/10.1002/pbc.26217

 

  1. Ragde H, Blasko JC, Grimm PD, et al., 1997, Interstitial iodine-125 radiation without adjuvant therapy in the treatment of clinically localized prostate carcinoma. Cancer, 80: 442–453. https://doi.org/10.1002/(sici)1097-0142(19970801)80:3<442:aid-cncr12>3.0.co;2-x

 

  1. Kuban DA, El-Mahdi AM, Schellhammer PF, 1989, I-125 interstitial implantation for prostate cancer. What have we learned 10 years later? Cancer, 63: 2415–2420. https://doi.org/10.1002/10970142(19890615)63:12<2415:aid-cncr2820631207>3.0.co;2-u

 

  1. Holm HH, Juul N, Pedersen JF, Hansen H, et al., 2002, Transperineal 125iodine seed implantation in prostatic cancer guided by transrectal ultrasonography. J Urol, 167: 985–988; discussion 988–989. https://doi.org/10.1016/s0022-5347(02)80320-2

 

  1. Davis BJ, Horwitz EM, Lee WR, et al., 2012, American Brachytherapy Society consensus guidelines for transrectal ultrasound-guided permanent prostate brachytherapy. Brachytherapy, 11: 6–19. https://doi.org/10.1016/j.brachy.2011.07.005

 

  1. Thompson I, Thrasher JB, Aus G, et al., 2007, Guideline for the management of clinically localized prostate cancer: 2007 update. J Urol, 177: 2106–2131.

 

  1. Meng N, Jiang Y, Wang J, et al., 2012, Permanent implantation of iodine-125 seeds as a salvage therapy for recurrent head and neck carcinoma after radiotherapy. Cancer Invest, 30: 236–242.

 

  1. Wang J, Chai S, Wang R, et al., 2019, Expert consensus on computed tomography-assisted three-dimensional-printed coplanar template guidance for interstitial permanent radioactive I seed implantation therapy. J Cancer Res Ther, 15: 1430–1434. https://doi.org/10.4103/jcrt.JCRT_434_19

 

  1. Zhou C, Zhang J, Zhang JG, et al., 2018, Iodine-125 brachytherapy alone for advanced primary parotid gland carcinoma. Int J Oral Maxillofac Surg, 47: 561–567. https://doi.org/10.1016/j.ijom.2017.03.038

 

  1. Zhu L, Jiang Y, Wang J, et al., 2013, An investigation of 125I seed permanent implantation for recurrent carcinoma in the head and neck after surgery and external beam radiotherapy. World J Surg Oncol, 11: 60. https://doi.org/10.1186/1477-7819-11-60

 

  1. Jiang YL, Meng N, Wang JJ, et al., 2010, CT-guided iodine-125 seed permanent implantation for recurrent head and neck cancers. Radiat Oncol, 5: 68. https://doi.org/10.1186/1748-717X-5-68

 

  1. Melchels FPW, Feijen J, Grijpma DW, 2010, A review on stereolithography and its applications in biomedical engineering. Biomaterials, 31: 6121–6130. https://doi.org/10.1016/j.biomaterials.2010.04.050

 

  1. Zopf DA, Hollister SJ, Nelson ME, et al., 2013, Bioresorbable airway splint created with a three-dimensional printer. N Engl J Med, 368: 2043–2045. https://doi.org/10.1056/NEJMc1206319

 

  1. Cohen J, Reyes SA, 2015, Creation of a 3D printed temporal bone model from clinical CT data. Am J Otolaryngol, 36: 619–624. https://doi.org/10.1016/j.amjoto.2015.02.012

 

  1. Hannen EJM, 2006, Recreating the original contour in tumor deformed mandibles for plate adapting. Int J Oral Maxillofac Surg, 35: 183–185. https://doi.org/10.1016/j.ijom.2005.07.012

 

  1. Hallermann W, Olsen S, Bardyn T, 2006, A new method for computer-aided operation planning for extensive mandibular reconstruction. Plast Reconstr Surg, 117: 2431–2437. https://doi.org/10.1097/01.prs.0000219076.83890.e8

 

  1. Huang M, Liu S, Zheng L, et al., 2012, A digital model individual template and CT-guided 125I seed implants for malignant tumors of the head and neck. J Radiat Res, 53: 973-977. https://doi.org/10.1093/jrr/rrs046

 

  1. Ji Z, Jiang Y, Guo F, et al., 2017, Dosimetry verification of radioactive seed implantation for malignant tumors assisted by 3D printing individual templates and CT guidance. Appl Radiat Isot, 124: 68–74. https://doi.org/10.1016/j.apradiso.2016.12.009

 

  1. Wang J, Zhang F, Guo J, et al., 2017, Expert consensus workshop report: Guideline for three-dimensional printing template-assisted computed tomography-guided (125)I seeds interstitial implantation brachytherapy. J Cancer Res Ther, 13: 607–612. https://doi.org/10.4103/jcrt.JCRT_412_17

 

  1. Huang MW, Zheng L, Liu SM, et al., 2013, 125I brachytherapy alone for recurrent or locally advanced adenoid cystic carcinoma of the oral and maxillofacial region. Strahlenther Onkol, 189: 502–507. https://doi.org/10.1007/s00066-013-0324-3

 

  1. Huang MW, Wu WJ, Lv XM, et al., 2018, The role of I interstitial brachytherapy for inoperable parotid gland carcinoma. Brachytherapy, 17: 244–249. https://doi.org/10.1016/j.brachy.2017.09.017

 

  1. Wu WJ, Huang MW, Zhang GH, et al., 2018, Mandibular growth in survivors of pediatric parotid gland carcinoma treated with interstitial brachytherapy. Pediatr Blood Cancer, 65: e27223. https://doi.org/10.1002/pbc.27223

 

  1. Fan Y, Huang M, Zhao Y, et al., 2017, Radioactive seed migration following parotid gland interstitial brachytherapy. Brachytherapy, 16: 1219–1224. https://doi.org/10.1016/j.brachy.2017.08.007

 

  1. Chen P, Wu W, Yi Z, et al., 2019, I interstitial brachytherapy in management of pediatric skull base tumors. Pediatr Blood Cancer, 66: e27622. https://doi.org/10.1002/pbc.27622

 

  1. Xu N, Zheng L, Wu WJ, et al., 2019, Definitive I brachytherapy of locally advanced adenoid cystic carcinoma involving the skull base with satisfying efficacy and safety. J Oral Maxillofac Surg, 77: 2143–2153. https://doi.org/10.1016/j.joms.2019.03.031

 

  1. Ren Y, Bu R, Zhang L, et al., 2013, Implantation of radioactive particles into the cranial base and orbital apex with the use of a magnetic resonance imaging-based surgical navigation system. Oral Surg Oral Med Oral Pathol Oral Radiol, 116: e473–e477. https://doi.org/10.1016/j.oooo.2012.01.047

 

  1. Xu X, Zhou F, Liu B, et al., 2019, Efficient multiple organ localization in CT image using 3D region proposal network. IEEE Trans Med Imaging, 38: 1885–1898. https://doi.org/10.1109/TMI.2019.2894854

 

  1. Liu SM, Wang HB, Sun Y, et al., 2016, The efficacy of iodine-125 permanent brachytherapy versus intensity-modulated radiation for inoperable salivary gland malignancies: Study protocol of a randomised controlled trial. BMC Cancer, 16: 193. https://doi.org/10.1186/s12885-016-2248-7
Conflict of interest
The authors declare that they have no conflicts of interest.
Share
Back to top
Advances in Radiotherapy & Nuclear Medicine, Electronic ISSN: 2972-4392 Published by AccScience Publishing
We use cookies on our website to ensure you get the best experience.
Read more about our cookies here
Accept