The 14th OR Young Editorial Board Forum was successfully held online, attracting more than 16,000 views through live streaming platforms including Scientific Cloud, Bilibili, and WeChat Video Channel. The forum was chaired by Dr. Long Bai, Deputy Director of the Institute of Biomedical Engineering and Interdisciplinary Research at Shanghai University and Director of the OR Editorial Office.

The forum brought together two outstanding young experts from leading universities, who shared their latest research achievements and clinical insights in the fields of nanomedicine, drug delivery systems, and translational biomedical research. The event received enthusiastic responses and promoted academic exchange within the global organoid research community.

Dr. Zhongmin Tang

Tongji University

Presentation Title: Development and Application of Metabolism-Regulating Nanomedicines

Dr. Tang introduced the development of nanomaterials as advanced platforms for drug delivery and functional regulation. His presentation highlighted how metabolism-regulating nanomedicine strategies can achieve precise disease intervention by modulating cellular metabolic pathways, remodeling pathological microenvironments, and enhancing therapeutic responses.

The report focused on key strategies for designing metabolism-targeted nanomedicines, including the construction of functional nanocarriers, controlled drug release, and metabolic reprogramming mechanisms. Through various disease models, particularly cancer therapy applications, Dr. Tang demonstrated the potential of nanomedicine in overcoming limitations of conventional treatments and improving therapeutic precision.

Prof. Keke Wu

Guangzhou Medical University

Presentation Title: Construction and Application of Novel Polyphenol-Based Nanodrug Delivery Systems (PDNPs)

Prof. Wu presented recent advances in polyphenol-based nanodrug delivery systems, focusing on the self-assembly properties of polyphenolic molecules, nanoplatform construction strategies, and functional regulation mechanisms.

The presentation highlighted how PDNP systems improve the stability and delivery efficiency of bioactive molecules while enabling multifunctional regulation in disease treatment and microenvironment modulation. These studies provide valuable insights into the development of next-generation nanotherapeutic platforms with enhanced delivery capabilities and biological functions.

Through cutting-edge discussions on nanomedicine and drug delivery technologies, the 14th OR Young Editorial Board Forum highlighted the growing integration of materials science, biomedical engineering, and life sciences. With the continued advancement of human-derived models such as organoids and microphysiological systems, nanomedicine development, evaluation, and optimization are expected to become increasingly precise and personalized.

OR will continue to promote interdisciplinary collaboration and scientific exchange, fostering the integration of nanomedicine and organoid research to advance discoveries in disease modeling, drug screening, and precision medicine.