AccScience Publishing / JCTR / Volume 3 / Issue 2 / DOI: 10.18053/jctres.03.201702.005
REVIEW

Importance of intellectual property generated by biomedical research  at universities and academic hospitals

Joris J Heus1* Elmar S.de Pauw1 Mirjam Leloux2 Margherita Morpurgo3,4 Michael R Hamblin5.6,7 Michal Hege8
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1 Innovation Exchange Amsterdam (IXA) Office AMC, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, the Netherlands
2 Innovation Exchange Amsterdam (IXA) Office UvA-HvA, University of Amsterdam, Science Park 904, Amsterdam, the Netherlands
3 Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Padova, Italy
4 Technology Transfer Office, University of Padova, Padova, Italy
5 Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, Massachusetts, United States
6 Department of Dermatology, Harvard Medical School, Boston, Massachusetts, United States
7 Harvard-MIT Division of Health Sciences and Technology, Cambridge, Massachusetts, United States
8 Department of Experimental Surgery, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands
Submitted: 4 November 2016 | Revised: 22 May 2017 | Accepted: 24 May 2017 | Published: 24 May 2017
© 2017 by the Author(s). This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution -Noncommercial 4.0 International License (CC-by the license) ( https://creativecommons.org/licenses/by-nc/4.0/ )
Abstract

Biomedical research has many different facets. Researchers and clinicians study disease biology and biochemistry to discover novel therapeutic targets, unravel biochemical pathways and identify biomarkers to improve diagnosis, or devise new approaches to clinically manage diseases more effectively. In all instances, the overall goal of biomedical research is to ensure that results thereof (such as a therapy, a device, or a method which may be broadly referred to as “inventions”) are clinically implemented. The development and implementation of an invention can be arduous and very costly. Historically, it has proven to be crucial to protect intellectual property (IP) rights to an invention (i.e., a patent) to ensure that companies can obtain a fair return on their investment that is needed to develop an academic invention into a product for the benefit of patients. However, the importance of IP is not generally acknowledged among researchers at academic institutions who are active in biomedical research. Therefore this paper aims to (1) raise IP awareness amongst clinical and translational researchers; (2) provide a concise overview of the steps that the patenting trajectory entails; and (3) highlight the importance of IP protection for both the research and the researcher. 

Relevance for patients: Adequate patent protection of inventions generated through biomedical research at academic institutions increases the probability that patients will benefit from these inventions, and indirectly enables the funding of clinical studies, mainly by opening up more opportunities for diversified funding (e.g. specific grants aimed at start-ups, pre-seed and seed capital) that otherwise would not be accessible. As a consequence, patented inventions are more likely to become clinically tested and reach the market, providing patients with more treatment options.

Keywords
invention
technological innovation
medical and pharmaceutical research
patents
protection
commercialization
Conflict of interest
The authors declare they have no competing interests.
References

[1] Pharmaceutical Research and Manufacturers of America  (PhRMA), “Drug Discovery and Development: Understanding  the R&D Process,” Feb 2007.  http://www.phrma.org/sites/default/files/pdf/rd_brochure_0223 07.pdf

[2] R. Boom et al. Journal of Clinical Microbiology, (1990) 28:  495-503, and  http://www.biomerieux-diagnostics.com/nuclisensr-easymagr

[3] https://worldwide.espacenet.com/publicationDetails/biblio?CC =NL&NR=6514306&KC=&FT=E&locale=en_ EP#

[4] https://www.google.nl/search?q=kuwait+harbour+incident+19 64&biw=975&bih=1048&source=lnms&tbm=isch&sa=X&ve d=0ahUKEwjn1LPQmZTRAhVBc1AKHbcNARcQ_AUIBig B&dpr=1.05#imgrc=k20QqTcKT7r6dM%3A

[5] Cohen J. How the battle lines over CRISPR were drawn. Science 2017; 2. February 15 news article. http://www.sciencemag.org/news/2017/02/how-battle-lines-ov er-crispr-were-drawn

[6] E. F. Damsgaard, M. C. Thursby. Industrial and Corporate  Change (2013) 22(1): 183-218.

[7] T. Hockaday. Phases of growth in university technology transfer. Les Nouvelles, December 2013, 275-279. [8] http://www.astp-proton.eu/?s=impact+report

[9] M. Heger. Drug delivery system for use in the treatment of  vascular and vessel-related pathologies. Submitted to the European Patent Office January 26, 2009, application # EP- 09151332.5. PCT application filed on July 26, 2010 with reference #: PCT/EP2010/050833.

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Journal of Clinical and Translational Research, Electronic ISSN: 2424-810X Print ISSN: 2382-6533, Published by AccScience Publishing