The advancement of next-generation cancer therapies plays a pivotal role in identifying new targets and the progression of precision oncology. This approach aims to customize treatments for individual patients based on the specific characteristics of their cancer. Nature is a rich source of potential anticancer drugs, with diverse chemicals and active compounds. Both natural products and synthetic analogs have been studied for cancer treatment.

We are currently inviting submissions of manuscripts associated with the title, including the anticancer activity of synthetic molecules and their mechanism of action with the anticancer activity of natural products, which is also covered in this special issue. These compounds should stem from either synthetic or natural sources and must be authenticated through in vitro in vivo or in silico evaluations of their mechanisms of action.

Authors are cordially invited to submit original research articles and review articles with a specific focus on the following topic “Cancer drug discovery from synthetic and natural sources”.