AccScience Publishing / ITPS / Volume 3 / Issue 1 / DOI: 10.36922/itps.v3i1.909
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Point-of-Care Testing for Autoimmune Rheumatic Diseases: Benefits and Barriers

Yashwant Kumar1 * Alka Bhatia2
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1 Department of Immunopathology, Post Graduate Institute of Medical Education and Research, Chandigarh, India
2 Experimental Medicine and Biotechnology, Post Graduate Institute of Medical Education and Research, Chandigarh, India
INNOSC Theranostics and Pharmacological Sciences 2020, 3(1), 909
Submitted: 29 April 2020 | Accepted: 26 January 2020 | Published: 24 July 2020
© 2020 by the Authors. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution -Noncommercial 4.0 International License (CC-by the license) ( )

Point-of-care testing (POCT) is a near-patient detection technique that could provide results within minutes. Compared to 
conventional laboratory testing, POCT is more beneficial particularly in emergency and urgent care settings. Detection of antinuclear antibodies and autoantibodies against extractable nuclear antigens are critical for the diagnosis and management of autoimmune rheumatic diseases (AIRD). At present, these autoantibodies are detected using conventional methods that take hours or days in centralized laboratories. POCT for AIRD is hardly practiced as they are chronic illnesses which are seen as clinical emergencies occasionally. Since POCT provides instant results, it may be life-saving in critically ill and confusing cases, particularly those admitted to intensive care units with multisystem organ failure. POCT is also very useful in rural and remote health-care centers, addressing the needs of emergent disease detection. This review aims to provide an overview of the potential use of POCT in AIRD as well as discuss the types, benefits, and shortcomings of POCT devices, and the hurdles that prevent their widespread clinical use.

Point-of-care testing
Autoimmune rheumatic disorders
Antinuclear antibodies

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Conflict of interest
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