Predictors of spiritual needs in Chinese cancer patients: The prominent roles of time since diagnosis, depression severity, and residential area
Introduction: Cancer patients often experience psychological distress that accompanies their physical symptoms; consequently, heightened spiritual needs may reflect an important coping response. In Chinese cultural settings, the manifestation of spirituality is significantly different from that suggested by Western paradigms, with greater emphasis on non-religious aspects of spirituality, including harmony between people and inner peace, than on traditional religious beliefs.
Objective: The current study aims to assess the spiritual needs of Chinese cancer patients in the hospital and to define sociodemographic, psychological, and clinical variables correlated with these needs using Chinese-validated instruments.
Methods: A cross-sectional study was conducted between February and April 2025, involving 189 cancer patients who presented to Shanxi Bethune Hospital in China. Participants were requested to complete the Chinese version of the 27-item Spiritual Needs Questionnaire (SpNQ-Ch-27), the Patient Health Questionnaire-9, and the Multidimensional Scale of Perceived Social Support. The data were analyzed using descriptive statistics, correlation analyses, and multiple linear regression.
Results: Participants reported moderate spiritual needs, with an average SpNQ-Ch-27 overall score of 37.23 (standard deviation = 16.91). The highest scores were obtained in the domains of active giving and inner peace, and the lowest in the religious domains, indicating a prevalence of a non-religious spiritual orientation. The predictors of spiritual needs identified using multivariate regression included a time since diagnosis of <6 months (β = 0.52, p<0.001), greater severity of depressive symptoms (β = 0.21, p=0.002), rural residence (β = 0.19, p=0.003), and low household income <3,000 RMB/month), which also showed a significant negative association (β = −0.14, p=0.029). The final model explained 78.9% of the variance in spiritual-needs scores.
Conclusion: Recently diagnosed cancer patients demonstrate the highest spiritual needs, with depression and socioeconomic vulnerability serving as additional risk factors. Chinese patients prioritize relational and existential spiritual dimensions over religious practices.
- Deo SV, Sharma J, Kumar S. GLOBOCAN 2020 report on global cancer burden: Challenges and opportunities for surgical oncologists. Ann Surg Oncol. 2022;29(11):6497-6500. doi: 10.1245/s10434-022-12151-6
- Shih JA, Moczynski W, Gallivan K, Balboni TA. “If it weren’t for my faith”: Spirituality in advanced cancer. Ann Palliat Med. 2019;8(5):758-762. doi: 10.21037/apm.2019.11.05
- He Y, Pang Y, Su Z, et al. Symptom burden, psychological distress, and symptom management status in hospitalized patients with advanced cancer: A multicenter study in China. ESMO Open. 2022;7(6):100595. doi: 10.1016/j.esmoop.2022.100595
- Riklikiene O, Tomkeviciute J, Spirgiene L, Valiuliene Z, Büssing A. Spiritual needs and their association with indicators of quality of life among non-terminally ill cancer patients: Cross-sectional survey. Eur J Oncol Nurs. 2020;44:101681. doi: 10.1016/j.ejon.2019.101681
- Büssing A, Koenig HG. Spiritual needs of patients with chronic diseases. Religions. 2010;1(1):18-27.doi: 10.3390/rel1010018
- Clark PA, Drain M, Malone MP. Addressing patients’ emotional and spiritual needs. Jt Comm J Qual Saf. 2003;29(12):659-670. doi: 10.1016/s1549-3741(03)29078-x
- Plessas D. Suffering and Serious Illness: Examining the Role of Non-Religious and Religious Meaning and Coping. Available from: https://theses.ubn.ru.nl/handle/123456789/19138 [Last accessed on 2026 Jan 08].
- Sun XH, Liu X, Zhang B, Wang YM, Fan L. Impact of spiritual care on the spiritual and mental health and quality of life of patients with advanced cancer. World J Psychiatry. 2021;11(8):449-462. doi: 10.5498/wjp.v11.i8.449
- Cheng Q, Xu X, Liu X, Mao T, Chen Y. Spiritual needs and their associated factors among cancer patients in China: A cross-sectional study. Support Care Cancer. 2018;26:3405-3412. doi: 10.1007/s00520-018-4119-z
- Cheng SL, Yusuf A, He YY, Tang WZ, Sulaiman NA. Spiritual needs and influencing factors of postoperative breast cancer women undergoing chemotherapy: A cross-sectional study. Risk Manag Healthc Policy. 2024;17:843-853. doi: 10.2147/rmhp.S453184
- Kang KA, Choi Y. Comparison of the spiritual needs of terminal cancer patients and their primary family caregivers. Korean J Hosp Palliat Care. 2020;23:55-70. doi: 10.14475/kjhpc.2020.23.2.55
- Zhao Y, Wang Y, Yao XY, Jiang L, Hou M, Zhao Q. Reliability and validity of the Chinese version of spiritual needs questionnaire with 27 items (SpNQ-Ch-27) in cancer patients. Int J Nurs Sci. 2019;6(2):141-147. doi: 10.1016/j.ijnss.2019.03.010
- Du S, Li K, Wang C, et al. Spiritual needs and their associated psychosocial factors among women with breast cancer: A cross-sectional study. J Adv Nurs. 2022;78(12):4113-4122. doi: 10.1111/jan.15416
- Ciria-Suarez L, Calderon C, Fernández Montes A, et al. Optimism and social support as contributing factors to spirituality in cancer patients. Support Care Cancer. 2021;29:3367-3373. doi: 10.1007/s00520-020-05954-4
- Büssing A, Balzat HJ, Heusser P. Spiritual needs of patients with chronic pain diseases and cancer - validation of the spiritual needs questionnaire. Eur J Med Res. 2013;18:64.
- Wang W, Bian Q, Zhao Y, et al. Reliability and validity of the Chinese version of the patient health questionnaire (PHQ-9) in the general population. Gen Hosp Psychiatry. 2014;36(5):539-544. doi: 10.1016/j.genhosppsych.2014.05.021
- Hinz A, Mehnert A, Kocalevent RD, et al. Assessment of depression severity with the PHQ-9 in cancer patients and in the general population. BMC Psychiatry. 2016;16:22. doi: 10.1186/s12888-016-0728-6
- Zimet GD, Dahlem NW, Zimet SG, Farley GK. The multidimensional scale of perceived social support. J Pers Assess. 1988;52(1):30-41.
- Wang X, Ma X, Yang M, et al. Proportion and related factors of depression and anxiety for inpatients with lung cancer in China: A hospital-based cross-sectional study. Support Care Cancer. 2022;30(6):5539-5549. doi: 10.1007/s00520-022-06961-3
- Tian X, Jin Y, Chen H, Tang L, Jimenez-Herrera MF. The positive effect of social support on psychological distress among Chinese lung cancer patients: The mediating role of self-esteem. Nurs Open. 2021;8(4):1642-1651. doi: 10.1002/nop2.793
- Sastra L, Büssing A, Chen CH, Yen MF, Lin ECL. Spiritual needs and influencing factors of Indonesian Muslims with cancer during hospitalization. J Transcult Nurs. 2021;32(3):212-220. doi: 10.1177/1043659620908926
- Nejat N, Rahbarian A, Shykhan R, Ebrahimpour S, Moslemi A, Khosravani M. Assessment of spiritual needs in cancer patients: A cross-sectional study. J Family Med Prim Care. 2023;12(5):894-901. doi: 10.4103/jfmpc.jfmpc_989_22
- Forouzi MA, Tirgari B, Safarizadeh MH, Jahani Y. Spiritual needs and quality of life of patients with cancer. Indian J Palliat Care. 2017;23(4):437-441. doi: 10.4103/ijpc.ijpc_53_17
- Sung H, Ferlay J, Siegel RL, et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021;71(3):209-249. doi: 10.3322/caac.21660
- Cao M, He L, Dianqin S, et al. Current cancer burden in China: Epidemiology, etiology, and prevention. Cancer Biol Med. 2022;19(8):1121-1138. doi: 10.20892/j.issn.2095-3941.2022.0231
- Shi X, Wang F, Xue L, et al. Current status and influencing factors of spiritual needs of patients with advanced cancer: A cross-sectional study. BMC Nurs. 2023;22(1):131. doi: 10.1186/s12912-023-01306-9
- Chen J, You H, Liu Y, Kong Q, Lei A, Guo X. Association between spiritual well-being, quality of life, anxiety and depression in patients with gynaecological cancer in China. Medicine (Baltimore). 2021;100(1):e24264. doi: 10.1097/md.0000000000024264
- Kroenke K, Spitzer RL, Williams JB. The PHQ-9: Validity of a brief depression severity measure. J Gen Intern Med. 2001;16(9):606-613. doi: 10.1046/j.1525-1497.2001.016009606.x
- Garduno-Ortega O, Morales-Cruz J, Hunter-Hernandez M, Gany F, Costas-Muniz R. Spiritual well-being, depression, and quality of life among latina breast cancer survivors. J Relig Health. 2021;60(3):1895-1907. doi: 10.1007/s10943-020-01147-9
- Usman FM, Jalal A, Bansal M, et al. The role of simulation in oncology nursing: A systematic review. Nurse Educ Pract. 2025;87:104466. doi: 10.1016/j.nepr.2025.104466
- Yuan J, Hu X, Jiao M, Wong TK, Chen L, Hu YL. Spiritual care experiences of nurses caring for cancer patients in China: A qualitative research. Support Care Cancer. 2025;33(8):723. doi: 10.1007/s00520-025-09786-y
- Pavlou M, Omar RZ, Ambler G. Penalized regression methods with modified cross‐validation and bootstrap tuning produce better prediction models. Biom J. 2024;66(5):e202300245. doi: 10.1002/bimj.202300245
- Von Elm E, Altman DG, Egger M, et al. The strengthening the reporting of observational studies in epidemiology (STROBE) statement: Guidelines for reporting observational studies. Int J Surg. 2014;12(12):1495-1499. doi: 10.1016/j.ijsu.2014.07.013
- Lee JY, Hong S. Psychological distress in newly diagnosed patients with gastrointestinal cancer: A scoping review. Asia Pac J Oncol Nurs. 2025;12:100672. doi: 10.1016/j.apjon.2025.100672
- Huang R, Li A, Ge H, et al. Impacts and pathways of behavioral activation on psychological distress among patients diagnosed with esophageal and gastric cancer in China: A randomized controlled trial. Cancer Med. 2024;13(19):e70314. doi: 10.1002/cam4.70314
- Huang P, He X, Li L, Xu J, Wang M, Li Y. A latent profile analysis of spiritual well-being and their relation to perceived social support and hope in patients with early-stage lung cancer. Support Care Cancer. 2025;33(1):14. doi: 10.1007/s00520-024-09045-6
- Feng Y, Liu X, Zhang S, Lin T, Guo X, Chen J. Relationship among post-traumatic growth, spiritual well-being, and perceived social support in Chinese women with gynecological cancer. Sci Rep. 2024;14(1):4847. doi: 10.1038/s41598-024-55605-5
- Rizalar S, Tufan A, Uslu R. Spirituality and hope levels of lung cancer patients who had surgery in Turkey. J Relig Health. 2023;62(3):2050-2064. doi: 10.1007/s10943-023-01773-z
- Ouyang D, Xie J. Buddhism without belonging: functional and digital forms of religious engagement among chinese youth. Religions. 2025;16(9):1108. doi: 10.3390/rel16091108
- Chou KL. Assessing Chinese adolescents’ social support: The multidimensional scale of perceived social support. Pers Individ Dif. 2000;28(2):299-307. doi: 10.1016/S0191-8869(99)00098-7
- Edelsbrunner PA, Simonsmeier BA, Schneider M. The Cronbach’s alpha of domain-specific knowledge tests before and after learning: A meta-analysis of published studies. Educ Psychol Rev. 2025;37(1):4. doi: 10.1007/s10648-024-09982-y
