AccScience Publishing / EJMO / Volume 2 / Issue 4 / DOI: 10.14744/ejmo.2018.91885
RESEARCH ARTICLE

Importance of Inflammatory Markers in Predicting Rupture in Ectopic Pregnancies

Emin Erhan Donmez1 Sevcan Arzu Arinkan1 Hasan Sut1 Reyyan Gokcen Iscan2 Fisun Vural1
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1 Department of Obstetrics and Gynecology, Haydarpasa Numune Training and Research Hospital, Istanbul, Turkey
2 Department of Obstetrics and Gynecology, Zeynep Kamil Women's and Children's Diseases Training and Research Hospital, Istanbul, Turkey
EJMO 2018, 2(4), 198–202; https://doi.org/10.14744/ejmo.2018.91885
Submitted: 15 March 2018 | Accepted: 25 April 2018 | Published: 10 October 2018
© 2018 by the Author(s). This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution -Noncommercial 4.0 International License (CC-by the license) ( https://creativecommons.org/licenses/by-nc/4.0/ )
Abstract

Introduction: The aim of the present study was to examine the laboratory findings and inflammatory markers in predicting rupture in patients who were admitted to our clinic with complaints of ectopic pregnancy.

Objective: One hundred fifty-four patients with tubal ectopic pregnancy who were diagnosed with ectopic pregnancy and treated were retrospectively examined.

Results: When the neutrophil lymphocyte ratios (NLRs) were compared between the two groups, the mean NLR values were 5.88±4.66 and 3.20±4.80 in the ruptured and unruptured groups, respectively, and the results were statistically significant (p=0.001). Similarly, the mean platelet lymphocyte ratio (PLR) values were 148.14±75.59 and 118.79±54.08 in the ruptured and unruptured groups, respectively, and the results were statistically significant (p=0.026). A statistically significant difference was found between the levels of beta human chorionic gonadotropin, white blood cell, PLR, and NLR in accordance with the presence of rupture in the patients (p<0.05), and the results of patients with ruptured ectopic pregnancy were found to be higher. The ratio of rupture risk was 4.5 times higher in patients with a PLR of ≥166.6, whereas it was 6.9 times higher in patients with an NLR of ≥4.

Conclusion: We believe that the inflammatory markers of NLR and PLR could be used for the prediction of rupture.

Keywords
Ectopic pregnancy
rupture
inflammatory markers
neutrophil lymphocyte ratios
platelet lymphocyte ratio
Conflict of interest
None declared.
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Eurasian Journal of Medicine and Oncology, Electronic ISSN: 2587-196X Print ISSN: 2587-2400, Published by AccScience Publishing