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RESEARCH ARTICLE

Effectiveness of Sildenafil in Erectile Sexual Dysfunction in Prostate Cancer Patients

Vilma Ávila Naún1* Jennifer Martínez Figueredo1 Rodolfo Martínez Chávez1 Terianne Pérez Viñals1
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1 Hospital General Docente “Dr. Agostinho Neto”, Guantanamo, Cuba
CP 2022, 4(1), 1–4;
© Invalid date by the Author(s). This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution 4.0 International License ( https://creativecommons.org/licenses/by/4.0/ )
Abstract

Introduction: Prostate cancer is the first cause of death by cancer in Cuban men and affects the quality of their sexual life. Objective: To investigate the efficacy of sildenafil in the treatment of erectile dysfunction in patients with prostate cancer after hormone or radiotherapy. Method: An observational, double perspective and cross-sectional study was conducted in the Service of Urology of Hospital “Dr. Agostinho Neto” in Guantanamo from 2014 to 2018, which was approved by the medical ethics committee. The study consisted of 70 patients diagnosed with prostate cancer who received hormone therapy or radiotherapy with erectile dysfunction. In each patient, we studied age, cancer treatment, time of postoperative dysfunction, and the response of penile erectile function to the use of sildenafil. Results: 37.2% of the patients were between 70 and 79 years old, and 79.1% of the patients received hormone therapy; the highest proportion of erectile dysfunction occurred 1–2 years after treatment (48.8%); 81.4% responded adequately to sildenafil treatment, which was not related to hormone or radiotherapy for cancer. Conclusions: Prostate cancer patients treated with hormone and/or radiotherapy benefit from the efficacy of sildenafil.

Keywords
Prostate cancer
Erectile sexual dysfunction
Sildenafil
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Cancer Plus, Electronic ISSN: 2661-3840 Print ISSN: 2661-3832, Published by AccScience Publishing