AccScience Publishing / ARNM / Volume 2 / Issue 1 / DOI: 10.36922/arnm.2828
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Cross-sectional imaging in symmetrical bilateral extranodal recurrence of follicular lymphoma: A case report

Cesare Oliveti1* Barbara Catalfamo2 Annachiara Mollace1 Claudia Italia Maria De Santis1 Roberta Mancini1 Giuseppe Lucio Cascini2 Francesco Manti1
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1 Department of Experimental and Clinical Medicine, Division of Radiology, Magna Graecia University of Catanzaro Azienda Ospedaliero-Universitaria Renato Dulbecco, Catanzaro, Calabria, Italy
2 Department of Diagnostic Imaging Nuclear Medicine Unit, Magna Graecia University of Catanzaro, Azienda Ospedaliero Universitaria Renato Dulbecco, Catanzaro, Calabria, Italy
Submitted: 26 January 2024 | Accepted: 19 March 2024 | Published: 27 March 2024
© 2024 by the Author(s). This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution 4.0 International License ( )

Follicular lymphoma (FL) constitutes nearly 30% of all lymphomas, making it the second most prevalent B-cell lymphoma. It exhibits an indolent course within the spectrum of non-Hodgkin lymphoma, with variable 5-year progression-free survival rates. Histologically graded 1–3, FL primarily affects bone marrow and lymphoid organs but may also involve extranodal tissues, such as bilateral muscle tissue. This report outlines the diagnostic challenges associated with disease recurrence in such unusual locations, emphasizing the need for vigilance among clinicians and radiologists. Through imaging and biopsy, we confirmed recurrence in the patient. The study highlights the role of 18F-FDG PET/CT in detecting uncommon FL sites and guiding treatment decisions while emphasizing the importance of multidisciplinary care for optimal patient management.

Follicular lymphoma
Computed tomography
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Conflict of interest
The authors declare that they have no competing interests.
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Advances in Radiotherapy & Nuclear Medicine, Electronic ISSN: 2972-4392 Published by AccScience Publishing