Adenoid Cystic Carcinoma of the Breast, a Rare Entity: Report of Two Cases and Review of Literature
Adenoid cystic carcinoma (ACC) is a rare special subtype of breast cancer, accounting for approximately 0.1% of all breast cancers. It is commonly seen in the salivary glands. The imaging findings of this rare tumor have not been well described in the literature. Histologically, ACC is a triple negative tumor with basal-like breast features (tumors that are devoid of estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2 expressions, and express basal cell markers). For the most part, ACC is low-grade, that is how they have a good prognosis, whereas there are a rare lymph node involvement and distant metastasis. In the current state of knowledge, Treatment is either simple mastectomy or lumpectomy with radiotherapy. There is no consensus on optimal treatment for patients with ACC. Otherwise, the role of chemotherapy and hormonal therapy remains controversial. Here, we report two cases occurred in female patients who presented with a palpable breast mass in the breast that turned out to be an ACC of the breast.
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